Green process of circular economy industry chain for co-production of industrial sulfanilamide and hydroxylamine products and organic acid downstream products

Abstract

The invention provides a green process of a circular economy industry chain for co-production of industrial sulfanilamide and hydroxylamine products and organic acid downstream products. The process comprises the following steps that hydrochloric acid mixed acid is separated and purified to obtain sulfuric acid and co-produced hydrochloric acid, and the obtained sulfuric acid enters a sulfuric acid mixed acid treatment route; partial co-produced hydrochloric acid and nitroalkane are subjected to a hydrolysis reaction to obtain organic mixed acid and co-produced hydroxylamine hydrochloride, and the organic mixed acid is separated and purified to obtain co-produced organic acid; the sulfuric acid mixed acid is separated and purified to obtain organic matters and co-produced sulfuric acid; the organic matters are subjected to reactive crystallization to co-produce p-aminobenzene sulfonic acid; and partial co-production sulfuric acid and nitroalkane are subjected to a hydrolysis reaction to obtain a co-production hydroxylamine sulfate product and organic mixed acid, and the organic mixed acid is separated to obtain co-produced organic acid. According to the process, a green circular economy industrial chain of industrial sulfanilamide is realized, and meanwhile, a green circular economy industrial chain of hydroxylamine products and organic acid downstream products can be co-produced.

Description

technical field [0001] The invention belongs to the field of the production process of chemical raw materials, and specifically relates to the recycling of raw materials and co-products used in the production of industrial sulfonamides and co-production of hydroxylamine products and downstream products of organic acids to realize the green technology of circular economy industrial chain. The field of chemical raw materials. Background technique [0002] In 1932, German chemists Josef Clara and Fritz Mitch synthesized Prontosil containing a sulfonamide group for the first time. In the same year, Gilha Dumark and others in Germany conducted animal experiments and found that it had the effect of anti-bacterial infection, and became the pioneer of medical application of sulfa drugs, and won the Nobel Prize in Medicine for this. Since then, various sulfa drugs have been continuously synthesized and widely used all over the world. According to incomplete statistics, there are cu...

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Problems solved by technology

[0008] The output of by-product hydrochloric acid and sulfuric acid in the entire pharmaceutical and chemical industry is huge. However, downstream customers have increasingly stringent quality requirements for by-product hydrochloric acid and by-product sulfuric acid. The hydrochloric acid and sulfuric acid by-products of industrial sulfonamides are difficult to meet the needs of customers, and the consumption of surrounding enterprises is limited. , most of the by-products hydrochloric acid and sulfuric acid need to be transported over long distances, resulting in a waste of resources and energy, thus severely restricting the development of sulfonamide pharmaceutical companies

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