Composition capable of promoting defecation and application thereof

A technology for promoting defecation and composition, applied in the field of compositions that can promote defecation, and can solve problems such as discount

Active Publication Date: 2021-12-31
GLACT BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, lactic acid bacteria are defined as a kind of live bacteria that are beneficial to the human body. If the number of lactic acid bacteria adhered or colonized in the intestinal tract is insufficient, the maintenance of intestinal balance and improvement of constipation will be greatly reduced

Method used

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  • Composition capable of promoting defecation and application thereof
  • Composition capable of promoting defecation and application thereof
  • Composition capable of promoting defecation and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030]

[0031] The 16s rRNA sequence analysis method and the API bacterial identification system are used to confirm the taxonomic characteristics of the bacterial strains. The characteristics of the bacterial strains of this embodiment are as shown in Table 2 in terms of morphology and general properties:

[0032] Table 2. Morphology and general properties of lactic acid bacteria strains

[0033]

[0034]

Embodiment 2

[0035]

[0036]The production of the lactic acid bacteria fermented powder of the present embodiment is to first cultivate the above-mentioned isolated Lactobacillus salivarius AP-32 strain and Lactobacillus plantarum LPL28 strain with a medium containing milk, milk powder, casein, soybean, bean products, or whey , Lactobacillus acidophilus TYCA06 strain, and Bifidobacterium longum subsp. infantis BLI-02 strain for fermentation. Next, after the culture medium is centrifuged to obtain the fermentation liquid, the strain activity of the fermentation liquid is removed by heat sterilization, the bacterial cells of the fermentation liquid are removed, or it is dried to form a dry powder. In addition, the dry powder can be used as the lactic acid bacteria fermented powder of this embodiment; and the fermented liquid deactivated by the strain or the fermented liquid removed from the bacteria is processed to form the lactic acid bacteria fermented powder of this embodiment.

Embodiment 3

[0037]

[0038] This embodiment tests the defecation-promoting effect of the lactic acid bacteria fermented powder of the above-mentioned embodiment in the human body. Firstly, 200 mg of lactic acid bacteria fermented powder and maltodextrin were mixed into capsules, so that the contents of the capsules reached 500 mg; another 500 mg of maltodextrin was made into capsules as a control group. Then, 45 subjects were divided into three groups, 15 in each group, and the weekly defecation frequency of each subject before the test was recorded. Afterwards, one group took a control capsule containing only maltodextrin every day, another group took one capsule containing 200mg lactic acid bacteria fermented powder daily, and the other group took three capsules containing 200mg lactic acid bacteria fermented powder daily for a period of one month , and record the number of defecation for each subject in the last week of taking.

[0039] Such as figure 1 As shown, the defecation fre...

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Abstract

The invention discloses a composition capable of promoting defecation. The composition comprises: lactic acid bacteria fermentation powder including lactic acid bacteria fermentation products, where the lactic acid bacteria fermentation products are obtained by culturing at least lactic acid bacteria strains in a culture medium containing milk, milk powder, casein, soybeans, bean products or whey, and wherein the lactic acid bacteria strain comprises a Lactobacillus salivarius AP-32 strain, a Lactobacillus plantarum LPL28 strain, a Lactobacillus acidophilus TYCA06 strain, a Bifidobacterium longum subsp. Infantis BLI-02 strain or a combination thereof; and a physiologically acceptable excipient, diluent, or carrier.

Description

technical field [0001] The present invention relates to a composition, and in particular to a composition capable of promoting defecation and its use. Background technique [0002] Constipation refers to a symptom of dry and hard stools and difficulty in defecation, leading to reduced defecation, usually due to insufficient large intestine peristalsis function, which delays the passage of stool in the large intestine or the discharge of rectum. If the feces stay in the rectum for too long, the decomposed food will be fermented by bacteria in the large intestine for a long time, and it is easy to produce toxins or harmful gases; if it cannot be discharged on time, the body will absorb these harmful substances again and further enter the blood. cause harm to the human body and contribute to many chronic or metabolic diseases. [0003] Most of the over-the-counter medicines for constipation, such as laxatives or stool softeners, but these common medicines will cause side effec...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/747A23C9/123A23C9/16A23C19/06A23F3/10A23F3/16A23F5/02A23F5/24A23L2/38A23L33/135A61P1/10A61K35/744A61K35/745
CPCA61K35/744A61K35/747A61K35/745A61P1/10A23L33/135A23C9/1234A23C19/062A23C9/16A23F3/10A23F3/166A23F5/02A23F5/246A23L2/382A23V2002/00A61K2300/00A23V2200/32A23V2200/3204
Inventor 何协勋陈敬伟郭易纬黄玉芬陈瑞芬林钲棋
Owner GLACT BIOTECH
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