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Prediction method for prognosis of patients with cancer, prediction method for effectiveness of Anti-cancer therapy, and selection method for therapy suitable for patients with cancer

A technology for patients and cancer, applied in the selection of suitable therapy for cancer patients, predicting the effectiveness of anti-cancer therapy for cancer patients, predicting the effectiveness of ketogenic diet therapy for cancer patients, predicting the prognosis of cancer patients, suitable therapy for cancer patients field, can solve the problem that there is no ketogenic diet therapy for cancer patients

Pending Publication Date: 2022-02-25
MEIJI CO LTD +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Although it was previously reported that the ketogenic diet is effective in the treatment of cancer (Patent Document 1), there is no simple index that can predict the effect of the ketogenic diet on cancer patients

Method used

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  • Prediction method for prognosis of patients with cancer, prediction method for effectiveness of Anti-cancer therapy, and selection method for therapy suitable for patients with cancer
  • Prediction method for prognosis of patients with cancer, prediction method for effectiveness of Anti-cancer therapy, and selection method for therapy suitable for patients with cancer

Examples

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Effect test

example 1

[0092] Example 1: The effect of predicting the prognosis of cancer based on the combination of blood albumin concentration, blood sugar level and blood CRP concentration as indicators

[0093] (1) Selection of subjects

[0094] The subjects were 55 (24 males, 31 females) cancer patients, and those who were stage 4, had a performance status score (PS) of 0 to 2, and were able to orally ingest it were targeted. The average age of the subjects was 55.8±12.1 years old, the average height was 162.3±8.7cm, and the average weight was 54.7±12.1kg. Among the diseases, there were 12 cases of lung cancer, 9 cases of colorectal cancer, 5 cases of breast cancer, 2 cases of bladder cancer, 2 cases of ovarian cancer, and 21 cases of other diseases. In addition, in the treatment history, there were 42 cases of chemotherapy, 32 cases of surgery, and 17 cases of radiation.

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Abstract

The purpose of the present invention is to provide a prediction method for prognosis of patients with cancer. The prediction method for prognosis of patients with cancer is characterized by using, as an index of prognosis, at least one index selected from the group consisting of an index of nutritional conditions, an index of sugar metabolism conditions, and an index of inflammation conditions in a patient with cancer. The index of nutritional conditions is preferably the concentration of albumin in the blood, the index of sugar metabolism conditions is preferably the concentration of glucose in the blood, and the index of inflammation conditions is preferably the concentration of CRP in the blood.

Description

[0001] References to related applications [0002] This application enjoys the priority of Japanese Patent Application No. 2019-127042 (filing date: July 8, 2019), which is an earlier Japanese application, and the entire disclosure thereof is made a part of this specification by reference. technical field [0003] The present invention relates to methods of predicting the prognosis of cancer patients. The present invention also relates to methods of predicting the effectiveness of anticancer therapies for cancer patients, and methods of selecting appropriate therapies for cancer patients. The present invention also relates to methods of predicting the prognosis of cancer patients on ketogenic diet therapy. The present invention also relates to: a method for predicting the effectiveness of ketogenic diet therapy for cancer patients, and a method for selecting a suitable therapy for cancer patients in ketogenic diet therapy. Background technique [0004] In recent years, wit...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/66G01N33/68
CPCG01N33/66G01N33/68G01N2333/765G01N2333/4737G01N2800/7028G01N2800/52G01N33/6827G01N33/574G01N33/6893
Inventor 萩原圭祐大佐贺智池田宣之高杉谕芦田欣也中村健太郎
Owner MEIJI CO LTD
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