Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!
Development of biomarker for ketogenic diet-based cancer treatment
What is Al technical title?
Al technical title is built by PatSnap Al team. It summarizes the technical point description of the patent document.
A ketogenic diet and cancer technology, applied in the field of biomarker development in the treatment of cancer ketogenic diet, can solve the problem of unknown details of the mechanism of action of ketogenic diet in cancer patients
Pending Publication Date: 2020-05-12
OSAKA UNIV +1
View PDF2 Cites 0 Cited by
Summary
Abstract
Description
Claims
Application Information
AI Technical Summary
This helps you quickly interpret patents by identifying the three key elements:
Problems solved by technology
Method used
Benefits of technology
Problems solved by technology
However, the effectiveness of ketogenic diet therapy has not been confirmed for all cancer patients, and the details of the mechanism of action of the effect of ketogenic diet in cancer patients are still unknown
Method used
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more
Image
Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
Click on the blue label to locate the original text in one second.
Reading with bidirectional positioning of images and text.
Smart Image
Examples
Experimental program
Comparison scheme
Effect test
Embodiment Construction
[0018] Hereinafter, embodiments of the present invention will be described in detail.
[0019] In the present invention, the ketogenic diet refers to a diet in which the ketogenic ratio (lipid: (protein+carbohydrate)) is about 2:1 to 1:1 by weight. The ketogenic diet therapy refers to taking such a ketogenic diet for a predetermined period of time (for example, 3 months), and there are no special restrictions on other nutrients. In the ketogenic diet therapy, the required trace elements and vitamins can be properly ingested using nutritional supplements.
[0020] "Cancer" as used herein includes, for example, tumors in which normal cells undergo mutations. Malignant tumors may arise from all organs and tissues in the body. Examples of cancer patients in this specification include lung cancer, ovarian cancer, bladder cancer, lip adenoid cystic carcinoma, kidney cancer, urothelial carcinoma, colorectal cancer, prostate cancer, and glioblastoma multiforme , pancreatic cancer, ...
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More
PUM
Login to View More
Abstract
Provided are a method for selecting cancer patients for which ketogenic diet therapy would be effective, and a method for predicting the effectiveness of ketogenic diet therapy on cancer patients. Theselection method is characterized by obtaining, from blood serum derived from a cancer patient prior to ingesting a ketogenic diet, analysis results for at least one pre-ingestion candidate substanceselected from the group consisting of acylcarnitine(12:0), acylcarnitine(12:1)-2, acylcarnitine(12:1)-3, acylcarnitine(14:1)-1, acylcarnitine(14:2)-1, acylcarnitine(14:2)-2, acylcarnitine(14:3)-2, acylcarnitine(16:1), acylcarnitine(16:2), anandamide, heptadecenoic acid, hypotaurine, linoleoylethanolamide, palmitoleic acid, palmitoylcarnitine, phytosphingosine, quinic acid, uric acid, alanine, citrulline, tryptophan, and lysine, and using the analysis results as an indicator.
Description
technical field [0001] The present invention relates to the development of biomarkers in the treatment of cancer with a ketogenic diet. Specifically, it relates to a method for selecting cancer patients who are effective in ketogenic diet therapy, and a method for predicting the effectiveness of ketogenic diet therapy for cancer patients. Background technique [0002] A "ketogenic diet" is known as one type of dietary therapy. "Ketogenic diet" is a high-fat food that restricts carbohydrates, and 60-90% of energy intake is taken from fat. Therefore, a "ketogenic diet" is utilized as a diet for treating patients requiring a carbohydrate-restricted diet, such as children with epilepsy (for example, Patent Document 1). [0003] In recent years, dietary therapy using this "ketogenic diet" has been proposed as a treatment method for cancer patients (for example, Patent Document 2). Cases have been found showing dramatic clinical results with ketogenic diet therapy. However, th...
Claims
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More
Application Information
Patent Timeline
Application Date:The date an application was filed.
Publication Date:The date a patent or application was officially published.
First Publication Date:The earliest publication date of a patent with the same application number.
Issue Date:Publication date of the patent grant document.
PCT Entry Date:The Entry date of PCT National Phase.
Estimated Expiry Date:The statutory expiry date of a patent right according to the Patent Law, and it is the longest term of protection that the patent right can achieve without the termination of the patent right due to other reasons(Term extension factor has been taken into account ).
Invalid Date:Actual expiry date is based on effective date or publication date of legal transaction data of invalid patent.