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Compositions and methods for improving hydration in individuals with dysphagia

A composition and individual technology, applied in the directions of drug combination, application, drug delivery, etc., can solve problems such as inability to use drug treatment, and achieve the effects of helping swallowing, reducing mortality, and improving refreshing feeling

Pending Publication Date: 2022-05-13
SOC DES PROD NESTLE SA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Oropharyngeal dysphagia, on the other hand, is a very serious condition and usually cannot be treated with medication

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment approach 1

[0081] Embodiment 1. A method of treating or preventing dehydration in an individual suffering from impaired swallowing, such as dysphagia, the method comprising administering to the individual an effective amount of a composition comprising a salivation agent and a cooling agent.

Embodiment approach 2

[0082] Embodiment 2. A method of treating or preventing dehydration in an individual suffering from dysphagia, the method comprising administering to the individual an effective amount of a composition comprising a salivation agent and a cooling agent, the salivation agent and the cooling agent The weight ratio of the agent is 1:0.06 to 1:0.2.

Embodiment approach 3

[0083] Embodiment 3. The method according to embodiment 1 or 2, wherein the salivation agent is one or more organic acids selected from the group consisting of fatty acids, ascorbic acid, citric acid, fumaric acid, lactic acid, malic acid and tartaric acid.

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PUM

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Abstract

The present invention relates to compositions and methods for improving hydration in a subject with dysphagia. More specifically, the present invention provides a method of treating or preventing dehydration in a subject suffering from a swallowing impairment, such as dysphagia, which may comprise administering to a subject suffering from dysphagia an effective amount of a composition comprising a salivating agent and a cooling agent in a weight ratio of 1: 0.06 to 1: 0.2. Optionally, the composition comprises a hemp thorn agent. The composition may be a powder that reconstitutes prior to administration, for example, upon drinking. A thickener or rarefied binder may be included in the powder and / or may be included in a liquid in which the powder is reconstituted. The composition may be a beverage comprising a salivating agent and a cooling agent in a total amount of at least 3.0% by weight of the beverage, for example at least 6.0% by weight of the beverage. The composition may be a ready-to-drink beverage or a frozen confection on a stick.

Description

[0001] This application is a divisional application of the application number 201780028210.3, the application date is June 2, 2017, and the invention title is "composition and method for improving hydration of individuals suffering from dysphagia". This application claims priority to US Provisional Application 62 / 3458363, filed June 3, 2016, the contents of which are incorporated herein by reference in their entirety. Background technique [0002] The present disclosure generally relates to compositions and methods for improving hydration in individuals suffering from impaired swallowing, such as dysphagia. More specifically, the present disclosure relates to administering to an individual suffering from dysphagia a composition comprising a salivating agent, a cooling agent, and optionally a tingling agent. [0003] Dysphagia is characterized by impaired involuntary motor control of the swallowing process and can cause "infiltration" (the entry of foreign material into the air...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/81A61K9/08A23L2/52A23L2/68A23L2/39A61P11/00A61P3/12A61P43/00A61K31/16A61K31/164A61K31/4525
CPCA61K31/16A61K31/164A61K31/4525A61K36/28A61K36/758A61K36/81A61K9/0095A61P11/00A61P3/12A61P43/00A23L2/52A23L2/68A23L2/39A23V2002/00A61K2300/00A23V2200/30A23V2250/21A23V2250/186A23V2250/708A23V2250/032A23V2250/036A23V2250/042A23V2250/044A23V2250/056A23V2200/242A23V2250/5086A23V2250/506A23V2250/50364A23V2250/5118A23V2250/5034A61K31/19A23L2/395A23L2/54A61K9/0056
Inventor D·P·拉贝J·A·斯万森A·伯比吉
Owner SOC DES PROD NESTLE SA
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