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Application of vitamin D in preparation of medicine or health care product for preventing and/or improving sarcopenia caused by aging

A technology for vitamins and health products, applied in the field of biomedicine, can solve problems to be further studied, and achieve the effects of good safety, increased pace, and small dosage

Pending Publication Date: 2022-07-08
TIANJIN MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

In these prevention and treatment methods, there are various types of nutrients, which have various important physiological functions, so they are considered to be an important means to prevent and treat sarcopenia. However, among the many nutrients, which nutrients can improve the state of muscle attenuation, Its mechanism of action remains to be further studied

Method used

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  • Application of vitamin D in preparation of medicine or health care product for preventing and/or improving sarcopenia caused by aging
  • Application of vitamin D in preparation of medicine or health care product for preventing and/or improving sarcopenia caused by aging
  • Application of vitamin D in preparation of medicine or health care product for preventing and/or improving sarcopenia caused by aging

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Embodiment Construction

[0029] Unless otherwise defined, technical terms used in the following embodiments have the same meanings as commonly understood by those skilled in the art to which the present invention belongs. The test reagents used in the following examples are conventional biochemical reagents unless otherwise specified; the experimental methods are conventional methods unless otherwise specified.

[0030] The present invention will be described in detail below with reference to the embodiments and the accompanying drawings.

[0031] 1. Research Design

[0032] A double-blind randomized intervention trial.

[0033] 2. Selection and exclusion criteria of study subjects

[0034] 2.1 Selection criteria: living in the community; vitamin D deficiency [according to the international seven-level classification of vitamin D nutritional status: serum 25-(OH)D concentration <50nmol / L]; sarcopenia over the age of 65 who can live independently ( The diagnostic criteria are as follows) elderly pop...

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Abstract

The invention discloses an application of vitamin D in preparation of a medicine or a health care product for preventing and / or improving sarcopenia caused by age increase, and a new medicinal value is explored for known vitamin D. Vitamin D can significantly enhance muscular strength, muscle quality, pace and other sarcopenia evaluation indexes, and effectively increase the level of insulin-like growth factor-1. The vitamin D disclosed by the invention has deep research and development values in the aspect of improving the sarcopenia, and provides a new research and development direction for preventing and improving the sarcopenia.

Description

technical field [0001] The invention belongs to the technical field of biomedicine, and particularly relates to the application of vitamin D in the preparation of medicines or health-care products for preventing and / or improving age-related sarcopenia. Background technique [0002] Sarcopenia (sarcopenia, sarcopenia) is a progressive age-related decrease in skeletal muscle mass, accompanied by decreased muscle strength and / or muscle function. "sarcopenia" is a new compound word first proposed by American researcher Rosenberg in 1989. The words "sarco" and "penia" both come from Greek and mean "meat, muscle" and "reduce, disappear," respectively, and are used to describe the state of muscle loss with age. [0003] The human body starts to lose muscle mass from the age of 40, and the average annual decrease is 1% to 2% after the age of 50, and the decrease in muscle mass can be as high as 50% after the age of 80. With the aging of the global population, it is expected that b...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/59A61K31/593A61P21/00
CPCA61K31/59A61K31/593A61P21/00
Inventor 牛凯军顾叶青孟革郑运良吴红梅王雪娜边姗姗张庭婧
Owner TIANJIN MEDICAL UNIV
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