Medicine composition for treating upper respiration channel infection and its preparing process

A composition and drug technology, applied in the direction of drug combination, medical formula, respiratory system diseases, etc., can solve the problems of poor curative effect of upper respiratory tract infection, lack of drugs for upper respiratory tract infection, poor curative effect, etc., and prolong thromboplastin time , Inhibit degranulation reaction, promote absorption effect

Inactive Publication Date: 2006-05-10
金陵药业股份有限公司技术中心
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The Chinese patent medicines currently on the market for treating upper respiratory tract infection can be divided into two categories: those mainly for clearing away heat and detoxifying throat, which are less effective in treating upper respiratory tract infection; The curative effect of these drugs is better for those with deficiency of fire and upper inflammation, but for those with Qi deficiency, especially those with phlegm coagulation and blood stasis syndrome, the curative effect is not good
There is a lack of drugs for the treatment of upper respiratory tract infections that take into account qi deficiency and blood stasis in the current market

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Embodiment 1. The preparation of pharmaceutical composition and granule thereof for the treatment of upper respiratory tract infection of the present invention

[0028] Take 1000 grams of Ligustrum lucidum, 500 grams of Radix Astragali, 500 grams of Salvia miltiorrhiza and 8000 milliliters of 90% ethanol, soak for 4 hours, reflux extraction for 1.5 hours, repeat the extraction three times, filter while hot, combine the alcoholic extracts three times, and keep the alcoholic extracts. Merge the medicinal dregs and 700 grams of lacquer, add 27000 ml of water to soak for 4 hours, decoct for 2 hours, extract twice in this way, combine the water extracts, filter, and concentrate the filtrate to a relative density of 1.05 (65 ° C thermal measurement), cool, add Ethanol makes the alcohol content reach 45%, let it stand for precipitation, take the supernatant, combine the supernatant with the above-mentioned ethanol extract, recover the ethanol, concentrate under reduced pressure...

Embodiment 2

[0030] Embodiment 2. The pharmaceutical composition for the treatment of upper respiratory tract infection of the present invention and the preparation of hard capsule thereof

[0031] Take 650 grams of Ligustrum lucidum, 200 grams of Astragalus membranaceus, and 200 grams of Salvia miltiorrhiza, add 3150 milliliters of 85% ethanol to soak for 4 hours, reflux extraction for 1.5 hours, filter while it is hot, collect the alcohol extract, and then repeatedly use 85% ethanol to reflux extract the dregs. The third time, the three alcoholic extracts were combined, and the alcoholic extracts were kept for use. Take alcohol-extracted medicinal residues and 400 grams of lacquer, add 11600 ml of water to soak for 5 hours, decoct for 1.5 hours, and extract in this way 3 times, combine the decoction, filter, and concentrate to a relative density of 1.03 (65 ℃ thermal measurement) . After cooling, add ethanol until the alcohol content is 40%. After standing for precipitation, keep the sup...

Embodiment 3

[0033] Embodiment 3. The preparation of the pharmaceutical composition and oral liquid thereof for the treatment of upper respiratory tract infection of the present invention

[0034] Take 200 grams of Ligustrum lucidum, 200 grams of Astragalus membranaceus, and 200 grams of Salvia miltiorrhiza, add 3000 ml of 95% ethanol to soak for 4 hours, reflux extraction for 1.5 hours, filter while it is hot, collect the alcohol extract, and repeatedly use 95% ethanol to reflux extract the dregs for 1 times, the alcoholic extracts were combined for two times, and the alcoholic extracts were kept for future use. Take alcohol-extracted medicinal residues and 100 grams of lacquer, add 10500 milliliters of water to soak for 5 hours, decoct for 1 hour, filter, concentrate to a relative density of 1.10 (65 ° C thermal measurement), cool, add ethanol to an alcohol content of 50 %, after settling down, keep the supernatant. The supernatant and the alcohol extract are combined, the ethanol is re...

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PUM

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Abstract

A pharmaceutical composition for treating upper respiratory tract infection and its industrially applicable preparation method, which is mainly composed of ethanol and water extracts of Ligustrum lucidum, Radix Astragali, Salvia miltiorrhiza, and lacquer lacquer, which is effective for acute and chronic pharyngitis, bronchitis , tonsillitis, etc., especially for chronic pharyngitis with complex diseases, nourishing the middle to clear, nourishing the middle and transforming, nourishing yin and Qi, resolving phlegm and removing blood stasis, and has the effect of treating both symptoms and root causes. The present invention uses modern extraction technology and pharmacological experiments. Concretely and characteristically present the treatment concept of synergistic multi-target, systemic regulation and local focus treatment unique to traditional Chinese medicine.

Description

technical field [0001] The invention relates to a medicinal composition for treating upper respiratory tract infection derived from traditional Chinese medicine and a preparation method thereof. Background technique [0002] Upper respiratory tract infections often cause inflammation of the trachea, throat, and tonsils, and are often closely related to general conditions. The Chinese patent medicines currently on the market for treating upper respiratory tract infection can be divided into two categories: those mainly for clearing away heat and detoxifying throat, which are less effective in treating upper respiratory tract infection; The curative effect of these drugs is better for those with deficiency fire and upper inflammation, but for those with Qi deficiency, especially those with phlegm coagulation and blood stasis syndrome, the curative effect is not good. The current market lacks medicines for the treatment of upper respiratory tract infections such as qi deficien...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/884A61K9/16A61K9/48A61K9/20A61K9/10A61P11/04A61P11/00
Inventor 孙志广陆茵王兴旺徐向阳孙晔张蕙张庆晓万辉田丽娟陈钟陈希张杰倪洁张春来夏云
Owner 金陵药业股份有限公司技术中心
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