Blood-cleaning detoxifying formulation and new preparing method
A technology of preparation and traditional Chinese medicine preparation, which is applied in the field of blood-purifying and detoxifying preparations and new preparations, and can solve the problems of many impurities, affecting clinical application, and large doses.
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Embodiment 1
[0065] The preparation method of dropping pill of the present invention:
[0066] prescription:
[0067] Rhubarb 133g Nepeta 66.5g Dandelion 66.5g
[0068] Fangfeng 66.5g Kudiding 66.5g Scutellaria baicalensis 66.5g
[0069] Forsythia 66.5g Licorice 66.5g White Akebia 66.5g
[0070] Rehmannia glutinosa 66.5g
[0071] PEG4000 100g
[0072] Makes 1000 pills
[0073] Preparation:
[0074] (1) Get forsythia, windproof, Nepeta, take supercritical extraction method (or steam distillation method), drop in the extraction kettle, when the pressure of the extraction kettle reaches 25Mpa, the pressure of the analysis kettle I reaches 6Mpa, and the pressure of the analysis kettle II reaches 6Mpa. At 6Mpa, cycle extraction starts, CO 2 The flow rate is about 20kg / h. After 2.5 hours of extraction, the material is discharged from the discharge port of the desorption kettle to obtain a yellow-green oily liquid, and the volatile oil is clathrated with β-cyclodextrin for later use;
[0...
Embodiment 2
[0078] The preparation method of soft capsule of the present invention:
[0079] prescription:
[0080] Rhubarb 533g Nepeta 266.5g Dandelion 266.5g
[0081] Fangfeng 266.5g Kudiding 266.5g Scutellaria baicalensis 266.5g
[0082] Forsythia 266.5g Licorice 266.5g Baimutong 266.5g
[0083] Rehmannia glutinosa 266.5g
[0084] PEG400 400g
[0085] Makes 1000 capsules
[0086] Preparation:
[0087] (1) Get forsythia, windproof, Nepeta, take supercritical extraction method (or steam distillation method), drop in the extraction kettle, when the pressure of the extraction kettle reaches 25Mpa, the pressure of the analysis kettle I reaches 6Mpa, and the pressure of the analysis kettle II reaches 6Mpa. At 6Mpa, cycle extraction starts, CO 2 The flow rate is about 20kg / h. After 2.5 hours of extraction, the material is discharged from the discharge port of the desorption kettle to obtain a yellow-green oily liquid, and the volatile oil is clathrated with β-cyclodextrin for later use...
Embodiment 3
[0091] The preparation method of granule of the present invention:
[0092] prescription:
[0093] Rhubarb 400g Nepeta 200g Dandelion 200g
[0094] Fangfeng 200g Kudiding 200g Scutellaria baicalensis 200g
[0095] Forsythia 200g Licorice 200g White Akebia 200g
[0096] Rehmannia glutinosa 200g
[0097] Made into 1000g
[0098] Preparation:
[0099] (1) take forsythia, windproof and Nepeta three medicinal materials and powder them into medicine;
[0100] (2) Take the remaining medicinal materials of the prescription, soak them with 65% ethanol for 60 minutes, then heat and reflux for 3 times, each time for 1 hour, combine the extracts, concentrate under reduced pressure to form a thick ointment, and set aside;
[0101] (3) Combine the above active ingredients, add 5.0 g of aspartame and 150.0 g of dextrin, granulate, dry, and spray 5.0 g of essence to obtain 1000 g of granules.
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