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Blood-cleaning detoxifying formulation and new preparing method

A technology of preparation and traditional Chinese medicine preparation, which is applied in the field of blood-purifying and detoxifying preparations and new preparations, and can solve the problems of many impurities, affecting clinical application, and large doses.

Inactive Publication Date: 2006-05-24
FUKANGREN BIO PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But in practice, because the medicine is prepared by powdering the medicinal materials into the medicine, there are many impurities and large doses, which seriously affect its clinical application.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0065] The preparation method of dropping pill of the present invention:

[0066] prescription:

[0067] Rhubarb 133g Nepeta 66.5g Dandelion 66.5g

[0068] Fangfeng 66.5g Kudiding 66.5g Scutellaria baicalensis 66.5g

[0069] Forsythia 66.5g Licorice 66.5g White Akebia 66.5g

[0070] Rehmannia glutinosa 66.5g

[0071] PEG4000 100g

[0072] Makes 1000 pills

[0073] Preparation:

[0074] (1) Get forsythia, windproof, Nepeta, take supercritical extraction method (or steam distillation method), drop in the extraction kettle, when the pressure of the extraction kettle reaches 25Mpa, the pressure of the analysis kettle I reaches 6Mpa, and the pressure of the analysis kettle II reaches 6Mpa. At 6Mpa, cycle extraction starts, CO 2 The flow rate is about 20kg / h. After 2.5 hours of extraction, the material is discharged from the discharge port of the desorption kettle to obtain a yellow-green oily liquid, and the volatile oil is clathrated with β-cyclodextrin for later use;

[0...

Embodiment 2

[0078] The preparation method of soft capsule of the present invention:

[0079] prescription:

[0080] Rhubarb 533g Nepeta 266.5g Dandelion 266.5g

[0081] Fangfeng 266.5g Kudiding 266.5g Scutellaria baicalensis 266.5g

[0082] Forsythia 266.5g Licorice 266.5g Baimutong 266.5g

[0083] Rehmannia glutinosa 266.5g

[0084] PEG400 400g

[0085] Makes 1000 capsules

[0086] Preparation:

[0087] (1) Get forsythia, windproof, Nepeta, take supercritical extraction method (or steam distillation method), drop in the extraction kettle, when the pressure of the extraction kettle reaches 25Mpa, the pressure of the analysis kettle I reaches 6Mpa, and the pressure of the analysis kettle II reaches 6Mpa. At 6Mpa, cycle extraction starts, CO 2 The flow rate is about 20kg / h. After 2.5 hours of extraction, the material is discharged from the discharge port of the desorption kettle to obtain a yellow-green oily liquid, and the volatile oil is clathrated with β-cyclodextrin for later use...

Embodiment 3

[0091] The preparation method of granule of the present invention:

[0092] prescription:

[0093] Rhubarb 400g Nepeta 200g Dandelion 200g

[0094] Fangfeng 200g Kudiding 200g Scutellaria baicalensis 200g

[0095] Forsythia 200g Licorice 200g White Akebia 200g

[0096] Rehmannia glutinosa 200g

[0097] Made into 1000g

[0098] Preparation:

[0099] (1) take forsythia, windproof and Nepeta three medicinal materials and powder them into medicine;

[0100] (2) Take the remaining medicinal materials of the prescription, soak them with 65% ethanol for 60 minutes, then heat and reflux for 3 times, each time for 1 hour, combine the extracts, concentrate under reduced pressure to form a thick ointment, and set aside;

[0101] (3) Combine the above active ingredients, add 5.0 g of aspartame and 150.0 g of dextrin, granulate, dry, and spray 5.0 g of essence to obtain 1000 g of granules.

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PUM

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Abstract

The present invention relates to a Chinese medicine composition and its preparation process. In particular, it relates to a Chinese medicine prescription for curing the diseases of sore, furuncle, sore-throat, conjunctival congestion, canker sore and toothache and its preparation process. Said Chinese medicine composition can be made into dripping pills and soft capsule preparation.

Description

Technical field: [0001] The invention relates to a traditional Chinese medicine composition and a preparation process thereof, in particular to a composition and a preparation process thereof for the initial stage of sore furuncle festering, scorching fever, sore throat, conjunctival congestion, aphthous sores and toothache. Background technique: [0002] In the early stage of boils and ulcers, scorching fever, sore throat, red eyes, mouth sores, and toothache are common clinical symptoms. Traditional Chinese medicine often adopts the methods of clearing away heat and detoxification, dispelling wind and reducing swelling, and the curative effect is remarkable. Qingxuejiedu pills are one of them. Represents medicine. However, in practice, because the medicine is prepared by powdering the medicinal materials, it leads to many impurities and large doses, which seriously affects its clinical application. [0003] Compared with ordinary pills, the preparation prepared by the ext...

Claims

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Application Information

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IPC IPC(8): A61K36/804A61K9/16A61K9/20A61K9/48A61P1/02A61P11/04
Inventor 刘露
Owner FUKANGREN BIO PHARMA
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