Inhibitors of phosphodiesterases in infertility

A technology of inhibitors and preparations, applied in the field of reproductive biology and assisted reproductive technology, can solve the problems of low success rate
CN1802177AInactive Publication Date: 2006-07-12LAB SERONO SA
18 Cites 6 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
LAB SERONO SA
Publication Date
2006-07-12
Estimated Expiration
Not applicable · inactive patent

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

The present invention is directed to methods of increasing oocyte production in a mammal. More specifically, the specification describes methods and compositions for inducing follicular maturation using a PDE inhibitor. The inhibitor may be used alone at high doses. Alternatively, the follicular maturation is achieved by combining a low dose of FSH with the PDE inhibitor treatment.
Need to check novelty before this filing date? Find Prior Art

Description

[0001] This application asserts U.S. Provisional Patent Application No. 60 / 458,955, filed April 1, 2003, U.S. Provisional Patent Application No. 60 / 470,434, filed May 15, 2003, U.S. Provisional Patent Application No. 60 / 470,434, filed January 28, 2004 Priority to Application No. 60 / 540,301 and U.S. Provisional Patent Application No. 60 / 544,003, filed February 12, 2004, the contents of each of which are incorporated herein by reference. technical field

[0002] The present invention relates generally to reproductive biology and assisted reproductive technologies (ART), such as controlled ovarian hyperstimulation (COH) for in vitro fertilization (IVF). More specifically, the present invention relates to methods and compositions for inducing follicle maturation in vivo, including stimulating follicle maturation, using one or more phosphodiesterase inhibitors alone, or in combination with one or more gonadotropins, Such as ovulation induction (OI). In addition, the present invent...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More