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Medicine composition for treating fatty liver and its preparing method

A technology of composition and fatty liver, which is applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc., and can solve the problems of undiscovered related reports

Inactive Publication Date: 2006-11-08
张平
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] No related reports about the composition of the present invention were found in the patent search

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0059] (1) The raw material medicine is composed of:

[0060] Capillary 600g Alisma 1000g Rhubarb 200g Turmeric 400g

[0061] Safflower 100g Bupleurum 400g Lycium barbarum 800g Licorice 400g;

[0062] (2) Add 6 times the amount of water to capillary, medlar, and licorice, heat and decoct twice for 2 hours each time, collect volatile oil at the same time, filter the medicinal liquid, and obtain water extracts such as capillary and turmeric, grind into coarse powder, Add 4 times the amount of water, steam distillation to extract the volatile oil, and separate the water extract and medicinal residues. Combine the water extracts such as capillary and turmeric water extracts, concentrate under reduced pressure to 60°C, the relative density is 1.05-1.10, and centrifuge at 10000r / min for 20 minutes, and the supernatant is concentrated under reduced pressure to 60°C. Density 1.20-1.25, vacuum-dried to obtain dry extract;

[0063] (3) Alisma, rhubarb, safflower, bupleurum and turmer...

Embodiment 2

[0067] (1) The raw material medicine is composed of:

[0068] Yin Chen 1000g Alisma 1400g Rhubarb 400g Turmeric 600g

[0069] 300g safflower, 600g bupleurum, 1200g medlar, 600g licorice;

[0070] (2) Add 10 times the amount of water to capillary, medlar, and licorice, heat and decoct twice for 2 hours each time, collect volatile oil at the same time, filter the medicinal liquid, and obtain water extracts such as capillary, turmeric, and grind it into a coarse powder. Add 8 times the amount of water, steam distillation to extract the volatile oil, and separate the water extract and medicinal residues. Combine the water extracts such as capillary and turmeric water extracts, concentrate under reduced pressure to 60°C, the relative density is 1.05-1.10, and centrifuge at 15000r / min for 40 minutes, and the supernatant is concentrated under reduced pressure to 60°C. Density 1.20-1.25, vacuum-dried to obtain dry extract;

[0071] (3) Alisma, rhubarb, safflower, Bupleurum and turm...

Embodiment 3

[0075] (1) The raw material medicine is composed of:

[0076] Capillary 800g Alisma 1200g Rhubarb 300g Turmeric 500g

[0077] Safflower 200g Bupleurum 500g Goji berries 1000g Licorice 500g;

[0078] (2) Add 8 times the amount of water to capillary, medlar, and licorice, heat and decoct twice, each time for 2 hours, and collect volatile oil (approx. Powder, add 6 times the amount of water, steam distillation to extract the volatile oil, separate the water extract and medicinal residues. Combine the water extracts such as capillary and turmeric water extracts, and concentrate under reduced pressure to 60 °C with a relative density of 1.05 to 1.10. Centrifuge at 12,000 r / min for 30 min in batches, concentrate the supernatant under reduced pressure to a relative density of 1.20-1.25°C at 60°C, and dry it in a vacuum to obtain a dry extract (yield: about 20.19%);

[0079] (2) Add 6 times the amount of 85% ethanol to Alisma, rhubarb, safflower, bupleurum and turmeric dregs, heat a...

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Abstract

The present invention belongs to the field of Chinese medicine technology, and especially a kind of medicine composition for treating fatty liver. The medicine composition is prepared with eight kinds of Chinese medicinal materials, including capillary artemisia, oriental water plantain, rhubarb, curcuma, safflower, etc. It has the functions of eliminating dampness and heat, dissipating blood stasis, draining turbid urine and nourishing liver, and is suitable for treating obese fatty liver. The present invention also discloses the preparation process of the medicine composition. The pharmacological and toxicological experiments prove the high curative effect and high safety.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a pharmaceutical composition for treating fatty liver and a preparation method thereof. technical background [0002] Fatty liver refers to the excessive accumulation of fat in liver cells caused by various reasons, and the fat content exceeds 5% of the liver weight (wet weight), or the intrahepatic steatosis caused by histologically exceeding 30% of the liver parenchyma. In recent years, the incidence of fatty liver in my country has been on the rise, and it has become the second largest liver disease after viral hepatitis. The incidence of fatty liver and liver fibrosis caused by various etiologies is as high as 25%, and about 1.5%-8.0% of patients can develop into liver cirrhosis. Therefore, it is of great significance to actively prevent and treat fatty liver. [0003] In the treatment of fatty liver, the current western medical treatment m...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P1/16
Inventor 张平
Owner 张平
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