Pharmaceutical composition for treating stubborn acne and application thereof

Abstract

The invention belongs to the field of pharmacy, and discloses a pharmaceutical composition for treating stubborn acne and application thereof. The pharmaceutical composition is mainly prepared from compound amino acid, vitamins and calcium gluconate, and in necessity, a therapeutically effective amount of antibiotics can be added. According to the main pathogenesis of the stubborn acne, targeted collaborative treatment is conducted, the metabolic activity of the human life can be quickly activated, and endocrine dyscrasia and hormone metabolism disorders are quickly corrected. The pharmaceutical composition has the effects of diminishing inflammation, reducing exudation, resisting angioneurotic edema, resisting allergy and the like, the functions of body's enzyme metabolism, diuresis, detoxification and brain and nervous system protection are promoted, the nutriture and the immunity function of a body are improved, disease alleviation and recovery of a patient suffering from the stubborn acne are facilitated, and the pharmaceutical composition is suitable for clinical popularization.

Description

technical field

[0001] The invention belongs to the field of pharmacy and relates to a pharmaceutical composition for treating intractable acne and its application. Background technique

[0002] 1. Intractable acne is a disease that is particularly prone to repeated attacks. It is very difficult to cure this disease: intractable acne is a skin disease that is prone to occur in the human body, and it is a particularly easy It is very difficult to cure the disease that recurs repeatedly. Acne, also known as acne, pimples, pimples, pimples, acne, etc., is a chronic inflammation of the pilosebaceous glands caused by embolism and sebum excretion disorders caused by hyperkeratosis of the skin. It usually occurs on the face, chest and back, often with blackheads The pathogenesis of acne, papulopustular nodules, cysts and other manifestations is not very clear, and some patients have relapsed for more than 9 years, which is very painful.

[0003] Intractable acne is generally caus...

Examples

Embodiment 1

[0073] Embodiment 1: Preparation example of pharmaceutical composition

[0074] A pharmaceutical composition, its component is:

[0075] Compound amino acid: containing 2.20g of isoleucine, 3.40g of leucine, 2.65g of lysine acetate, 0.30g of methionine, 0.40g of phenylalanine, 1.15g of threonine, and 0.38 of tryptophan g, valine 2.65g, arginine 2.20g, histidine 1.18g, glycine 1.57g, alanine 2.08g, proline 1.78g, aspartic acid 0.63g, asparagine 0.14g, N-acetyl-L-cysteine ​​0.20g, glutamic acid 1.43g, ornithine hydrochloride 0.42g, serine 0.93g, N-acetyl-L-tyrosine 0.22g, made into 250ml liquid;

[0076] Vitamins: Vitamin B 6 Add 3g and vitamin C 2g to 250ml 0.9% sodium chloride injection;

[0077] Calcium gluconate: 10ml of 10% calcium gluconate was added to 50ml of 0.9% sodium chloride injection;

[0078] Compound amino acids, vitamins, and calcium gluconate can be divided into three groups and formulated for intravenous infusion sequentially; compound amino acids and vit...

Embodiment 2

[0079] Embodiment 2: Preparation example of pharmaceutical composition

[0080] A pharmaceutical composition, its component is:

[0081] Compound amino acid: containing 2.20g of isoleucine, 3.40g of leucine, 2.65g of lysine acetate, 0.30g of methionine, 0.40g of phenylalanine, 1.15g of threonine, and 0.38 of tryptophan g, valine 2.65g, arginine 2.20g, histidine 1.18g, glycine 1.57g, alanine 2.08g, proline 1.78g, aspartic acid 0.63g, asparagine 0.14g, N-acetyl-L-cysteine ​​0.20g, glutamic acid 1.43g, ornithine hydrochloride 0.42g, serine 0.93g, N-acetyl-L-tyrosine 0.22g, made into 250ml liquid;

[0082] Vitamins: Vitamin B 6 Add 3-5g and 2g of vitamin C to 250ml 0.9% sodium chloride injection;

[0083] Calcium gluconate: 10ml of 10% calcium gluconate was added to 50ml of 0.9% sodium chloride injection;

[0084] Compound amino acids, vitamins, calcium gluconate, and Rocephine can be divided into four groups and prepared for intravenous infusion sequentially; compound amino ...

Embodiment 3

[0085] Embodiment 3: Preparation example of pharmaceutical composition

[0086] A pharmaceutical composition, its component is:

[0087] Compound amino acid: containing 4.40g of isoleucine, 6.80g of leucine, 5.30g of lysine acetate, 0.60g of methionine, 0.80g of phenylalanine, 2.30g of threonine, and 0.75g of tryptophan g, valine 5.30g, arginine 4.40g, histidine 2.35g, glycine 3.15g, alanine 4.15g, proline 3.55g, aspartic acid 1.25g, asparagine 0.27g, N-acetyl-L-cysteine ​​0.40g, glutamic acid 2.85g, ornithine hydrochloride 0.83g, serine 1.85g, N-acetyl-L-tyrosine 0.43g, mixed into 500ml liquid;

[0088] Vitamins: Vitamin B 6 Add 3-5g and 2g of vitamin C to 250ml 0.9% sodium chloride injection;

[0089] Calcium gluconate: 10ml of 10% calcium gluconate was added to 50ml of 0.9% sodium chloride injection;

[0090] Rocephine (ceftriaxone sodium for injection): Rocephine 2g was added to 100ml 0.9% sodium chloride injection;

[0091] Compound amino acids, vitamins, calcium gl...

technical field

[0001] The invention belongs to the field of pharmacy and relates to a pharmaceutical composition for treating intractable acne and its application. Background technique

[0002] 1. Intractable acne is a disease that is particularly prone to repeated attacks. It is very difficult to cure this disease: intractable acne is a skin disease that is prone to occur in the human body, and it is a particularly easy It is very difficult to cure the disease that recurs repeatedly. Acne, also known as acne, pimples, pimples, pimples, acne, etc., is a chronic inflammation of the pilosebaceous glands caused by embolism and sebum excretion disorders caused by hyperkeratosis of the skin. It usually occurs on the face, chest and back, often with blackheads The pathogenesis of acne, papulopustular nodules, cysts and other manifestations is not very clear, and some patients have relapsed for more than 9 years, which is very painful.

[0003] Intractable acne is generally caus...

Examples

Embodiment 1

[0073] Embodiment 1: Preparation example of pharmaceutical composition

[0074] A pharmaceutical composition, its component is:

[0075] Compound amino acid: containing 2.20g of isoleucine, 3.40g of leucine, 2.65g of lysine acetate, 0.30g of methionine, 0.40g of phenylalanine, 1.15g of threonine, and 0.38 of tryptophan g, valine 2.65g, arginine 2.20g, histidine 1.18g, glycine 1.57g, alanine 2.08g, proline 1.78g, aspartic acid 0.63g, asparagine 0.14g, N-acetyl-L-cysteine ​​0.20g, glutamic acid 1.43g, ornithine hydrochloride 0.42g, serine 0.93g, N-acetyl-L-tyrosine 0.22g, made into 250ml liquid;

[0076] Vitamins: Vitamin B 6 Add 3g and vitamin C 2g to 250ml 0.9% sodium chloride injection;

[0077] Calcium gluconate: 10ml of 10% calcium gluconate was added to 50ml of 0.9% sodium chloride injection;

[0078] Compound amino acids, vitamins, and calcium gluconate can be divided into three groups and formulated for intravenous infusion sequentially; compound amino acids and vit...

Embodiment 2

[0079] Embodiment 2: Preparation example of pharmaceutical composition

[0080] A pharmaceutical composition, its component is:

[0081] Compound amino acid: containing 2.20g of isoleucine, 3.40g of leucine, 2.65g of lysine acetate, 0.30g of methionine, 0.40g of phenylalanine, 1.15g of threonine, and 0.38 of tryptophan g, valine 2.65g, arginine 2.20g, histidine 1.18g, glycine 1.57g, alanine 2.08g, proline 1.78g, aspartic acid 0.63g, asparagine 0.14g, N-acetyl-L-cysteine ​​0.20g, glutamic acid 1.43g, ornithine hydrochloride 0.42g, serine 0.93g, N-acetyl-L-tyrosine 0.22g, made into 250ml liquid;

[0082] Vitamins: Vitamin B 6 Add 3-5g and 2g of vitamin C to 250ml 0.9% sodium chloride injection;

[0083] Calcium gluconate: 10ml of 10% calcium gluconate was added to 50ml of 0.9% sodium chloride injection;

[0084] Compound amino acids, vitamins, calcium gluconate, and Rocephine can be divided into four groups and prepared for intravenous infusion sequentially; compound amino ...

Embodiment 3

[0085] Embodiment 3: Preparation example of pharmaceutical composition

[0086] A pharmaceutical composition, its component is:

[0087] Compound amino acid: containing 4.40g of isoleucine, 6.80g of leucine, 5.30g of lysine acetate, 0.60g of methionine, 0.80g of phenylalanine, 2.30g of threonine, and 0.75g of tryptophan g, valine 5.30g, arginine 4.40g, histidine 2.35g, glycine 3.15g, alanine 4.15g, proline 3.55g, aspartic acid 1.25g, asparagine 0.27g, N-acetyl-L-cysteine ​​0.40g, glutamic acid 2.85g, ornithine hydrochloride 0.83g, serine 1.85g, N-acetyl-L-tyrosine 0.43g, mixed into 500ml liquid;

[0088] Vitamins: Vitamin B 6 Add 3-5g and 2g of vitamin C to 250ml 0.9% sodium chloride injection;

[0089] Calcium gluconate: 10ml of 10% calcium gluconate was added to 50ml of 0.9% sodium chloride injection;

[0090] Rocephine (ceftriaxone sodium for injection): Rocephine 2g was added to 100ml 0.9% sodium chloride injection;

[0091] Compound amino acids, vitamins, calcium gl...

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