18 results about "Blood corpuscles" patented technology

The utility model discloses a portable peripheral blood cell counter which comprises a glass slide and a cover glass, and the cover glass is positioned at the upper end of the glass slide; the carrying and placing frame is arranged at the lower end of the glass slide, a rectangular placing open groove is formed in the upper end face of the carrying and placing frame, L-shaped positioning pieces are fixed to the four corners of the upper end of the rectangular placing open groove in the carrying and placing frame, and the glass slide is located in the rectangular placing open groove and clamped among the four L-shaped positioning pieces; the semicircular through groove is formed in the middle of the front end face and the rear end face of the carrying and placing frame, and the semicircular through groove vertically penetrates through the carrying and placing frame. According to the blood cell counter, external protection of glass slides and cover glass is achieved, the effect that each group of cover glass and glass slides are separated is achieved, and therefore the problems that a main body of an existing blood cell counter used for counting is made of glass slides and cover glass, the glass slides and the cover glass are prone to colliding with each other during placement, damage can occur, and peripheral blood cell counting is affected are effectively solved.

The invention discloses a clinical examination A box integrated with biochemical detection equipment, and belongs to the technical field of emergency medical rescue, the clinical examination A box comprises a box body, a box cover and a support structure, the outer surface of the box body close to the upper end is provided with a locking structure; the box cover and the box body are limited through a locking structure; the supporting structure is installed on the lower end face of the box body. Wherein a detection instrument integrating a dry type blood cell analyzer, a dry type biochemical analyzer, a dry type immune biochemical analyzer, a urine analyzer and a thermal printer is placed in the box body, a limiting assembly is arranged in the middle of the upper end face of the box cover, and during clinical examination, the detection instrument is placed on the limiting assembly; besides, the biochemical detection instruments are integrated together and then placed in the box body, and the integrated biochemical detection instruments can be directly taken out and then placed on the box cover for direct use during use, so that the use is relatively convenient, and a good use prospect is achieved.

State of art techniques for measurement of blood viscosity, RBC concentration and the like are in vitro methods. Embodiments of the present disclosure provide a method and system for in vivo non-invasive measurement of blood parameters using Laser Enabled Swept Frequency Acoustic Interferometry (LE-SFAI) principle. A Continuous Wave Laser diode based Photo Acoustic (CWPA) signal in frequency domain generated from laser excitation incident on a biological tissue of a subject carrying blood vessel is acquired by the ultrasound sensor and converted to a windowed time domain CWPA signal limited to two peaks. The signal characteristics such as risetime, amplitude, and time difference between first peak and the second peak are obtained to derive blood viscosity, Red Blood Corpuscles (RBC) concentration, and blood vessel diameter.

The present invention discloses a high-precision positioning mechanism for a small valve sleeve for medical blood cells, comprising a product carrier, a blocking assembly, a guide positioning assembly, a sleeve pressure correction assembly, and a limit lifting assembly. The product carrier comprises at least two groups, at least two groups of product carriers are placed on a transmission assembly, and at least two products are placed on the product carrier; a buffer station and a correction station are sequentially provided on the transmission assembly along the transmission direction; the blocking assembly is provided at the buffer station; the guide positioning assembly and the limit lifting assembly are provided at the correction station; the guide positioning assembly is located on both sides of the transmission assembly and is provided with a guide channel along the transmission direction; the limit lifting assembly is provided inside the transmission assembly and outputs power in the vertical direction; the sleeve pressure correction assembly is provided at the correction station and is located above the transmission assembly for correcting the positioning of the product carrier. The present invention realizes the sleeve pressure side positioning correction of multiple groups of shells and sleeves before assembly, effectively improving the relative position accuracy of the sleeve and shell during assembly.

The invention relates to the technical field of medical data processing, and discloses a blood cell analyzer for tumor cell recognition and a method thereof, and the method comprises the following steps: adding epithelial-mesenchymal transition phenotype specific fluorescent dye for double staining; focusing the dyed sample into a single-row liquid flow, and enabling the single-row liquid flow to sequentially pass through a detection area; synchronously collecting a multispectral photoacoustic signal, a laser scattering signal and an impedance signal of the cells in the liquid flow; carrying out fusion processing on the collected multi-dimensional signals, and extracting morphological characteristics, biochemical characteristics and acoustic characteristics of the cells; the extracted features are input into a pre-trained improved convolutional neural network model, a tumor cell recognition result and type judgment are output, and the types comprise an epithelial type, a mesenchymal type or a mixed type; and outputting a detection report. According to the invention, automatic, high-precision and rapid identification of tumor cells in a blood sample is realized, the detection cost is reduced, and a reliable basis is provided for early screening and diagnosis of tumors.

The application belongs to the technical field of biological medicine, and relates to an anticoagulant and application thereof in white blood cell classification for high-precision animal blood cell analyzers. The anticoagulant comprises two parts of buffer and anticoagulant matrix components and active components. In the anticoagulant, the buffer and anticoagulant matrix component formula comprises 1.5-2 g of citrate, 0.3-0.5 g of citric acid and 0.15-0.20 g of EDTA-K2 per 100 mL of the anticoagulant, and the active component comprises 0.08-0.10 g of low-molecular enzymatic hydrolysis carboxymethyl chitosan, 1.0-1.2 g of hydroxypropyl-beta-cyclodextrin, 10-15 mg of dipyridamole and 8-10 mg of aspirin. The anticoagulant effectively inhibits platelet activation, prevents platelet aggregation and white blood cell morphological deformation, accurately identifies in white blood cell five classification, and has a classification accuracy as high as 98%, and is suitable for veterinary clinical hematology examination and animal disease monitoring.

The invention discloses a device for detecting five-classification blood cells and MxA to identify viral infection. The device comprises a DIFF reaction detection system, an MxA immunofluorescence detection system, a sample collection system, a first DIFF reagent pipeline and a second DIFF reagent pipeline, a collected sample is conveyed to the DIFF reaction detection system through the sample collection system, a first DIFF reagent in a first DIFF reagent pool is guided to the DIFF reaction detection system through the first DIFF reagent pipeline, and a second DIFF reagent in a second DIFF reagent pool is guided to the second DIFF reaction detection system through the second DIFF reagent pipeline. A second DIFF reagent pipeline is used for guiding a second DIFF reagent in a second DIFF reagent pool to a DIFF reaction detection system, so that DIFF reaction detection is completed in the DIFF reaction detection system, a collected sample is conveyed to an MxA immunofluorescence detection system through a sample collection system, a first pushing unit is used for pushing an MxA reagent card strip on the uppermost layer of an MxA reagent card strip stacking unit to a conveying unit, and a second pushing unit is used for pushing a second DIFF reagent card strip on the uppermost layer of the MxA reagent card strip stacking unit to the conveying unit. The conveying unit is used for conveying the MxA reagent card strip to sequentially pass through the photometry and incubation unit and the reading unit, so that the device can quickly complete the detection of the individual viral infection and the degree thereof.

The invention discloses a blood visible component detection microscopic examination sample single-step dyeing preparation method. The method comprises the following steps: T10, collecting a blood sample of a detection object by using a blood collection tube; t20, taking the volume VT of the blood sample by using a pipette, and adding the blood sample into a reagent tube filled with a dilution staining reagent to obtain a microscopic examination sample, wherein the volume of the dilution staining reagent in the reagent tube is VA; diluting the blood sample by using the dilution staining reagent; t30, taking a microscopic examination sample with the volume equal to that of VB by using a pipette, and adding the microscopic examination sample into a sample adding opening of the blood visible component detection chip at one time; the dilution staining reagent comprises a staining agent, and the staining agent is used for staining cells in the blood sample; the dilution staining reagent comprises a protective agent, and the protective agent acts on a cell membrane in a blood sample, so that the cell membrane is stable and is not easy to break. The operation steps and the volume relation of various turbid liquid components added in each link are defined in detail, so that the preparation of the microscopic examination sample is more efficient, and the subsequent high-precision analysis and identification can be supported.

The application belongs to the technical field of cell culture, and particularly relates to a method for determining the number of particles in a unit volume of liquid and application. The method comprises the following steps: (1) using a dye to dye the liquid to be measured, and sequentially dropping the dyed liquid to be measured and a chromatographic separation liquid at one end of filter paper, the particles in the liquid to be measured are dispersed on the filter paper under the action of capillary chromatography, and the number of particles in the liquid to be measured is obtained by naked-eye counting; (2) according to the volume of the liquid to be measured, the number of particles in a unit volume of liquid is calculated. The determination method of the application does not need to purchase expensive instruments, does not need to take photos and use image analysis software for auxiliary counting, breaks through the limitation that a blood cell counter cannot determine particles with a particle size greater than 100 mu m, and can complete the determination of the number of particles by naked-eye observation, which is simple, efficient and low in cost.

The utility model provides a blood collection tube mounting mechanism of a blood cell analyzer, which comprises a mounting base, a blood collection tube transposition mechanism arranged on the left side of the mounting base, a sample output mechanism arranged on the right side of the mounting base, and a left support plate fixedly mounted on the left side of the mounting base, a lifting seat is fixedly mounted at the top of the left supporting plate, and a connecting seat is detachably connected to the top of the lifting seat. Through the design of the blood collection tube transposition mechanism, a plurality of soft blood collection tubes can be mounted and supported, meanwhile, the soft blood collection tubes which are not inspected can be driven to an inspection station, and through the design of the sample output mechanism, the soft blood collection tubes can be extruded, so that samples in the soft blood collection tubes are output from the bottom and then fall down under the action of gravity; the blood cell analyzer is used for testing, namely, the function of automatically switching and testing a plurality of samples is achieved, the automation degree of the instrument is improved, and the efficiency of other work of an operator is improved.

The invention relates to the technical field of fermentation production and product quality control, in particular to a rapid counting method for bradyrhizobium. The rapid counting method specifically comprises the following steps: diluting bradyrhizobium, mixing the diluted bradyrhizobium with methylene blue dye liquor for dyeing, and then performing pulsed electric field assisted dyeing, and counting by using a blood cell counting plate to obtain the effective viable count of the bradyrhizobium. The methylene blue dye liquor specifically comprises a methylene blue aqueous solution and a phosphate buffer which are mixed according to the volume ratio of 1: 1; the methylene blue aqueous solution comprises the following components by concentration: 0.1-0.3% of methylene blue; 0.3 to 1.7 percent of beta-cyclodextrin; 3 to 5% of PEG-4000 (polyethylene glycol 4000); 0.01% to 0.05% of Triton X-100; and 0.02 to 0.2 percent of carboxymethyl chitosan. According to the rapid counting method provided by the invention, the effective viable count can be obtained within 2 hours, and the result accuracy is relatively high.

The invention relates to the technical field of liquid paths of tablet pushers, in particular to a liquid path system of a tablet pusher and a control method, which comprises the following steps: a sampling needle moves downwards to collect blood, pre-discharges a small amount of blood to eliminate back clearance, and drips blood; cleaning the sampling needle and the push broach, blow-drying the push broach, and discharging waste liquid; the plunger pump M1 is pulled down to pump the maintenance solution into the sampling needle, after soaking is conducted for a period of time, the plunger pump M2 pumps pure water, the liquid path system is filled with the maintenance solution, and the air pump P2 is started to fill the corresponding reagent, according to the control method, single-needle blood sampling and blood dripping are adopted, the needed blood amount is small, dilution is avoided, and the problems of blood dilution and large blood sample consumption caused by a common double-needle system are solved; ultrasonic waves and pure water are used for cleaning the push broach, high-pressure air is used for blow-drying, the push broach is clean, pollution is not carried, the single-test cost is low, the sampling needle is cleaned with a blood cell diluent, blood is kept stable in the sampling needle, pure water cleaning is switched during shutdown, the phenomenon that the service life of a pump, a valve and the sampling needle is affected by crystallization is avoided, and meanwhile the single-test cost is reduced.

The present invention provides filter paper for red blood cell collection, the filter paper being used for separating and collecting red blood cells from blood, said filter paper being characterized by comprising glass filter paper and a water-absorbing sheet, and the glass filter paper being overlapped on the water-absorbing sheet. Also provided is a method for analyzing the fatty acid composition in a red blood cell membrane using the aforementioned filter paper for red blood cell collection.

1. Name of the design product: Laboratory cell counter. 2. Use of the design product: The present design patent is applicable to the classification and counting of blood cells in the laboratory of hospitals at all levels. 3. Design points of the design product: in shape. 4. Picture or photo that best indicates the design points: perspective view.

The invention provides a river and lake algae breeding early warning method which comprises the following steps: collecting river endogenous bottom mud containing dormant algae as an inoculum, and collecting river overlying water as an algae activation culture medium; mixing the bottom mud and overlying water according to a specific proportion, then putting the mixture into a constant-temperature illumination incubator, and culturing for a specific time under the optimal external condition for simulating algae breeding so as to activate dormant algae in the bottom mud and form dominant algae species; and carrying out optical microscope microscopic examination on the cultured mud-water mixture, analyzing dominant algae species, and carrying out algae counting by using a blood cell counting plate. The method is easy and convenient to operate, expensive instruments and equipment are not needed, dominant algae species analysis and algae counting can be completed only through the optical microscope and the blood cell counting plate, and the early warning cost is reduced. The method fills the technical blank of early warning of algae outbreak, provides effective technical support for ecological environment protection of river and lake water, and is suitable for popularization and application in various river and lake water bodies.

The present invention provides filter paper for red blood cell collection, the filter paper being used for separating and collecting red blood cells from blood, said filter paper being characterized by comprising glass filter paper and a water-absorbing sheet, and the glass filter paper being overlapped on the water-absorbing sheet. Also provided is a method for analyzing the fatty acid composition in a red blood cell membrane using the aforementioned filter paper for red blood cell collection.

The present invention provides a sample analysis method and a sample analysis system. The sample analysis system includes a first sample analyzer, a second sample analyzer, and a sample transportation device. The first sample analyzer is a hematology analyzer for detecting the to-be-tested whole blood sample to obtain a blood routine test result. The second sample analyzer is an analyzer for detecting the to-be-tested whole blood sample to obtain a corresponding test result. The sample analysis method includes: obtaining first detection data of the to-be-tested whole blood sample on the first sample analyzer and second detection data of the to-be-tested whole blood sample on the second sample analyzer; obtaining an actual correction parameter corresponding to the to-be-tested whole blood sample according to the first detection data; obtaining an actual test result corresponding to the to-be-tested whole blood sample according to the second detection data; and correcting the actual test result according to the actual correction parameter. The present invention can improve the accuracy of the test result.

A centrifuge and a rotor for the centrifuge are provided, which reduce the deviation of the amount of washing liquid supplied into a plurality of test tubes in a washing liquid injection process of a centrifuge for washing biological cells such as blood cells. A washing liquid distribution element installed at an upper side portion of a rotor main body includes an upper side distribution element and a lower side distribution element. In rotation of the rotor, washing liquid is supplied from a washing liquid guide inlet and enters a concave inner side portion of the lower side distribution element. The washing liquid that enters the inner side portion moves by centrifugal force in a manner of climbing an inclined portion from the vicinity of a rotation center toward the radial outside. A lower side circular ring portion at a front end of the inclined portion is formed with a plurality of washing liquid passages in a radial pattern. Washing liquid is discharged from radial outside from a spout of the washing liquid passage. By forming the inclined portion, the washing liquid can be equally distributed into each test tube.