2 results about "Reproductive process" patented technology

This invention relates to the field of image analysis technology, specifically to a real-time monitoring and culture system for embryonic development during assisted reproductive technology. It includes: an image data acquisition module for acquiring grayscale images of embryos; an image information content analysis module for determining the splitting information content and sharpness information content of each embryo grayscale image based on changes in the number of edge pixels and differences in pixel grayscale values; a target embryo image screening module for screening target embryo images based on the differences in splitting information content and sharpness information content of the embryo grayscale images; and an embryonic development monitoring module for comparing the similarity features of edge lines in all target embryo images to identify high-information-content embryo images for embryonic development monitoring. This invention can accurately screen embryo images with high reference value, thereby reducing data redundancy and improving the accuracy of embryonic development monitoring.

The application belongs to the technical field of genetic engineering, and discloses a uterus-specific Ctcf Construction method and application of an infertility animal model based on uterus-specific knockout. The research results show that CTCF deletion leads to complete loss of fertility in mice, which is manifested as implantation failure and blocked decidualization response. Unlike the embryonic lethality caused by systemic CTCF knockout, the uterus-specific knockout strategy mediated by Pgr-Cre successfully avoids the problem of early death, making it possible to study the function of CTCF in the adult uterus. The model provides an ideal tool for studying the physiological function of CTCF in the female reproductive process. In addition, the model shows a clear and stable infertility phenotype, and can be used as a platform for screening fertility drugs or studying decidualization mechanisms.