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287results about "Diarylmethane dyes" patented technology
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Compound Having S1P Receptor Binding Potency and Use Thereof
InactiveUS20080207584A1Easy to optimizeEasy to separateBiocideNervous disorderAutoimmune conditionS1P Receptor
Provided are: a compound represented by formula (I):(wherein ring A and ring D each represent a cyclic group which may have a substituent(s); E and G each represent a bond or a spacer having 1 to 8 atoms in its main chain; L represents a hydrogen atom or a substituent; X represents amino which may have a substituent(s), or a heterocyclic group which contains at least one nitrogen atom and which may have a substituent(s); n represents 0 to 3, in which when n is 2 or more, a plurality of ring A's may be the same or different from one another); a salt thereof; an N-oxide form thereof; a solvate thereof, a prodrug thereof; and a medicament which includes those. The compound represented by formula (I) is capable of binding S1P receptors (in particular, EDG-1 and / or EDG-6), and useful for preventing and / or treating rejection in transplantation, autoimmune diseases, allergic diseases, etc.
Owner:ONO PHARMA CO LTD
Light-emitting material for organo-electroluminescence device and for organic electroluminescence device which the material is applied
InactiveUS6280859B1Methine/polymethine dyesOrganic chemistryOrganic electroluminescenceLight emission
A light-emitting material which serves to emit light having a high brightness and is almost free of deterioration in light emission, and an organic EL device for which the light-emitting material is adapted, the material having the formula [1],
Owner:TOYO INK SC HOLD CO LTD
Process for producing dispersible and conductive Nano Graphene Platelets from non-oxidized graphitic materials
ActiveUS20100056819A1Impart dispersibilityImpart solubilityMaterial nanotechnologyPigmenting treatmentDisplay deviceSolar cell
The present invention provides a process for producing nano graphene platelets (NGPs) that are both dispersible and electrically conducting. The process comprises: (a) preparing a pristine NGP material from a graphitic material; and (b) subjecting the pristine NGP material to an oxidation treatment to obtain the dispersible NGP material, wherein the NGP material has an oxygen content no greater than 25% by weight. Conductive NGPs can find applications in transparent electrodes for solar cells or flat panel displays, additives for battery and supercapacitor electrodes, conductive nanocomposite for electromagnetic wave interference (EMI) shielding and static charge dissipation, etc.
Owner:GLOBAL GRAPHENE GRP INC
Organic photoconductive material electrophotographic photoreceptor and image forming apparatus using the same
ActiveUS7416824B2Highly reliable electrophotographic photoreceptorHigh sensitivityOrganic chemistryOrganic compound preparationEnaminePhenyl group
According to the present invention, an enamine compound having a specific structure is used as an organic photoconductive material. This enamine compound is obtained based on asymmetrical secondary naphtylamine which is readily available at a lowest price, by introducing phenyl groups containing substituents, as constituents units of the enamine part and presents excellent compatibility with binder resins, will not present detrimental effects such as partial crystallization at film forming and have a high charge mobility. The compound is able to realize highly reliable electrophotographic photoreceptor and an image forming apparatus which present a high electrostatic potential, high sensitivity and high enough light response and are excellent in durability and will not degrade in these characteristics under a low-temperature environment or in a high-speed process and will not lower in these characteristics even due to exposure to light.
Owner:SHARP KK
Process for producing dispersible and conductive nano graphene platelets from non-oxidized graphitic materials
Owner:GLOBAL GRAPHENE GRP INC
Anti tubercular drug: compositions and methods
Methods and compositions for treating disease caused by infectious agents, particularly tuberculosis. In particular, methods and compositions comprising substituted ethylene diamines for the treatment of infectious diseases are provided. In one embodiment, these methods and compositions are used for the treatment of mycobacterial infections, including, but not limited to, tuberculosis.
Owner:SEQUELLA +1
Alkoxy compounds for disease treatment
ActiveUS7982071B2Reducing ischemiaPrevent degradationBiocideSenses disorderAlkoxy groupDisease treatment
Owner:ACUACELA INC
Benzofluorene compound, emission materials and organic electroluminescent device
InactiveUS20080160347A1Improve featuresEasy to synthesizeOrganic chemistryDischarge tube luminescnet screensArylOrganic electroluminescence
Provided is a benzofluorene compound which exhibits excellent performances when applied to an organic electroluminescent device.In the benzofluorene compound, a central five-membered ring in a benzofluorene skeleton is substituted with aryl, and a benzene ring condensed to the five-membered ring is substituted with aryl, diarylamino and the like.
Owner:JNC CORP
Triaryl methane compounds and analogues thereof useful for the treatment or prevention of sickle cell disease or diseases characterized by abnormal cell proliferation
InactiveUS6028103AReducing sickle erythrocyte dehydrationDelaying occurrenceHalogenated hydrocarbon active ingredientsBiocideAbnormal cellSickled erythrocytes
The present invention provides a class of chemical compounds useful as efficacious drugs in the treatment of sickle cell disease and diseases characterized by unwanted or abnormal cell proliferation. The active compounds are substituted triaryl methane compounds or analogues thereof where one or more of the aryl groups is replaced with a heteroaryl, cycloalkyl or heterocycloalkyl group and / or the tertiary carbon atom is replaced with a different atom such as Si, Ge, N or P. The compounds inhibit mammalian cell proliferation, inhibit the Gardos channel of erythrocytes, reduce sickle erythrocyte dehydration and / or delay the occurrence of erythrocyte sickling or deformation.
Owner:HARVARD COLLEGE PRESIDENT & FELLOWS OF +2
Fluorene derivative, light-emitting element, light-emitting device, electronic device, and lighting device
ActiveUS20110095678A1High color purityImprove efficiencyOrganic chemistryDischarge tube luminescnet screensPhenyl groupLight emitting device
An object is to provide a new fluorene derivative as a good light-emitting material for organic EL elements. A fluorene derivative represented by General Formula (G1) is provided.In the formula, R1 to R8 separately represent a hydrogen atom, an alkyl group having 1 to 6 carbon atoms, a substituted or unsubstituted phenyl group, or a substituted or unsubstituted biphenyl group. Further, α1 to α4 separately represent a substituted or unsubstituted phenylene group. Ar1 represents a substituted or unsubstituted condensed aromatic hydrocarbon having 14 to 18 carbon atoms forming a ring. Ar2 represents a substituted or unsubstituted aryl group having 6 to 13 carbon atoms forming a ring. Ar3 represents an alkyl group having 1 to 6 carbon atoms or a substituted or unsubstituted aryl group having 6 to 12 carbon atoms. Further, j, m, and n separately represent 0 or 1, and p represents 1 or 2.
Owner:SEMICON ENERGY LAB CO LTD
Process for preparing methylene diphenylamines by partial neutralization of acidic methylene diphenylamines
Owner:BAYER CORPORATION
Light-emitting material for organo-electroluminescence device and for organic electroluminescence device which the material is applied
InactiveUS20010033944A1Organic chemistryMethine/polymethine dyesOrganic electroluminescenceLight emission
A light-emitting material which serves to emit light having a high brightness and is almost free of deterioration in light emission, and an organic EL device for which the light-emitting material is adapted, the material having the formula (1) disclosed in claim 1, 2 or 3.
Owner:TOYO INK SC HOLD CO LTD
Sulfonated diarylrhodamine dyes
Sulfonated diarylrhodamine compounds are useful as fluorescent labels of nucleosides, nucleotides, polynucleotides, and polypeptides. The compounds find particular application in the area of fluorescent nucleic acid analysis, e.g., automated DNA sequencing and fragment analysis, detection of probe hybridization in hybridization arrays, detection of nucleic acid amplification products, and the like.
Owner:APPL BIOSYSTEMS INC
Diphenylmethane compound
ActiveUS20100249374A1Superior in broad utilityImprove stabilityOrganic compound preparationDiaryl/thriaryl methane dyesDiphenylmethaneOrganic synthesis
Compounds having a diphenylmethane skeleton are superior in broad utility and stability, and are useful as a protecting reagent (anchor) of amino acid and / or peptide in the liquid phase synthesis and the like of a peptide having a C-terminal etc., which are of a carboxamide(-CONHR)-type, and in organic synthetic reaction methods (particularly peptide liquid phase synthetic methods), and may be contained in a kit for peptide liquid phase synthesis.
Owner:AJINOMOTO CO INC
Process for the preparation of polyamines of the diphenylmethane series at a low degree of protonation
ActiveUS20060287555A1Reduce the probability of reactionLong dwell timeIsocyanic acid derivatives preparationOrganic compound preparationDiphenylmethaneProtonation
The invention provides a process for the preparation of polyamines of the diphenylmethane series. This process comprises a) reacting aniline and formaldehyde in a molar ratio of 1.5:1 to 6:1, in the presence of an acid catalyst at temperatures of 20° C. to 100° C., in which the water content in the acid reaction mixture is <20 wt. % and a degree of protonation of <15% is established, and b) increasing the temperature of the reaction to a temperature of 110° C. to 250° C. when the ratio of the weight contents of p-aminobenzylaniline to 4,4′-MDA in the reaction mixture falls below a value of 1.00.
Owner:COVESTRO DEUTSCHLAND AG
Process for the preparation of polyamines of the diphenylmethane series at a low degree of protonation
ActiveUS7253321B2Reduce the probability of reactionLong dwell timeIsocyanic acid derivatives preparationOrganic compound preparationDiphenylmethaneMethylaniline
The invention provides a process for the preparation of polyamines of the diphenylmethane series. This process comprisesa) reacting aniline and formaldehyde in a molar ratio of 1.5:1 to 6:1, in the presence of an acid catalyst at temperatures of 20° C. to 100° C., in which the water content in the acid reaction mixture is <20 wt. % and a degree of protonation of <15% is established, andb) increasing the temperature of the reaction to a temperature of 110° C. to 250° C. when the ratio of the weight contents of p-aminobenzylaniline to 4,4′-MDA in the reaction mixture falls below a value of 1.00.
Owner:COVESTRO DEUTSCHLAND AG
Catalytic preparation of aryl methyl ketones using a molecular oxygen-containing gas as the oxidant
InactiveUS20030144554A1Speed up the conversion processIncrease turnover frequencyGroup 5/15 element organic compoundsCopper organic compoundsArylEthyl group
Owner:THE HONG KONG POLYTECHNIC UNIV +1
Indeno-fused ring compounds
The present invention relates to compounds represented by the following Formulas (I) and (II),Ring-A of Formulas I and II can be, for example, an aryl group, and Q′ and Q′″ can each be independently selected from groups, such as, halogen, —OH, —CN, amine groups, amide groups, carboxylic acid ester groups, carboxylic acid groups, alkenyl groups, alkynyl groups, carbonate groups, sulfide groups, and sulfonic acid ester groups. The present invention also relates to photochromic compositions and photochromic articles that include one or more photochromic compounds, such as represented by Formula II.
Owner:TRANSITIONS OPTICAL INC
Highly-fluorescent and photo-stable chromophores for enhanced solar harvesting efficiency
ActiveUS20130074927A1Improve photovoltaic performanceDesirable optical propertyOrganic chemistrySolid-state devicesSolar cellSolar energy harvesting
The invention provides highly fluorescent materials comprising a single (n=0) or a series (n=1, 2, etc.) of benzo heterocyclic systems. The photo-stable highly luminescent chromophores are useful in various applications, including in wavelength conversion films. Wavelength conversion films have the potential to significantly enhance the solar harvesting efficiency of photovoltaic or solar cell devices.
Owner:CHOSHU IND
Process for the preparation of di- and polyamines of the diphenylmethane series
InactiveUS20060094897A1Organic compound preparationDiaryl/thriaryl methane dyesDiphenylmethaneAniline
The present invention relates to a process for the preparation of di- and polyamines of the diphenylmethane series, and to the preparation of di- and polyisocyanates of the diphenylmethane series from these di- and poly-amines. The di- and poly-amines of the diphenylmethane series are prepared by the reaction of aniline and formaldehyde in the presence of hydrochloric acid. In with the present invention, the hydrochloric acid employed contains less than 0.001 wt. % of metal ions which are divalent and / or more than divalent.
Owner:BAYER MATERIALSCIENCE AG
Psycho-pharmaceuticals
InactiveUS20110034562A1Improve cognitive abilityRelieve symptomsOrganic active ingredientsBiocidePsychoactive drugAgonist
The invention provides a selective Sigma 1 or Dopamine D3 receptor agonist or a 5HT2c receptor ligand for use in the treatment of symptoms of anxiety and / or depression associated with an affective disorder and / or symptoms associated with cognitive impairment disorder. Particularly useful are diphenhydramine derivatives of Formula (I) and particularly (2-[(4-butylsulfanylphenyl)-phenyl-methyl]sulfanyl-N,N-dimethyl-ethanamin) (Captodiamine).
Owner:UNIV COLLEGE DUBLIN NAT UNIV OF IRELAND DUBLIN
Substituted phenethylamines with serotoninergic and/or norepinephrinergic activity
Owner:ACADIA PHARMA INC
Compound having S1P receptor binding potency and use thereof
InactiveUS8039674B2Improve permeabilityLess side effectsBiocideNervous disorderHydrogen atomS1P Receptor
Provided are: a compound represented by formula (I):(wherein ring A and ring D each represent a cyclic group which may have a substituent(s); E and G each represent a bond or a spacer having 1 to 8 atoms in its main chain; L represents a hydrogen atom or a substituent; X represents amino which may have a substituent(s), or a heterocyclic group which contains at least one nitrogen atom and which may have a substituent(s); n represents 0 to 3, in which when n is 2 or more, a plurality of ring A's may be the same or different from one another); a salt thereof; an N-oxide form thereof; a solvate thereof, a prodrug thereof; and a medicament which includes those. The compound represented by formula (I) is capable of binding S1P receptors (in particular, EDG-1 and / or EDG-6), and useful for preventing and / or treating rejection in transplantation, autoimmune diseases, allergic diseases, etc.
Owner:ONO PHARMA CO LTD
Targeted cellular delivery of nanoparticles
The various embodiments of the present disclosure relate generally to compositions and methods for the targeted cellular delivery of nanoparticles. More particularly, the various embodiments of the present invention are directed to the cellular delivery of nanoparticles tethered to a ligand by way of a poly(ethylene glycol) linkage, wherein the ligand demonstrates a binding specificity for a cellular target. In an exemplary embodiment, the ligand is tamoxifen and the cellular target is the estrogen receptor, which is upregulated in many breast cancer cells.
Owner:GEORGIA TECH RES CORP
Process for preparing diamines and polyamines from the diphenylmethane series
ActiveUS7528283B2Organic compound preparationDiaryl/thriaryl methane dyesDiphenylmethanePolymer science
The invention provides an improved process for preparing diamines and polyamines from the diphenylmethane series by reacting aniline and formaldehyde in the presence of an acid catalyst, the improvement involving the aniline containing less than about 3 wt. % of diamines and polyamines from the diphenylmethane series, based on the weight of the aniline.
Owner:COVESTRO DEUTSCHLAND AG
Substituted phenethylamines with serotoninergic and/or norepinephrinergic activity
Chemical syntheses and medical uses of novel inhibitors of the uptake of monoamine neurotransmitters and pharmaceutically acceptable salts and prodrugs thereof, for the treatment and / or management of psychotropic disorders, anxiety disorder, generalized anxiety disorder, depression, post-traumatic stress disorder, obsessive-compulsive disorder, panic disorder, hot flashes, senile dementia, migraine, hepatopulmonary syndrome, chronic pain, nociceptive pain, neuropathic pain, painful diabetic retinopathy, bipolar depression, obstructive sleep apnea, psychiatric disorders, premenstrual dysphoric disorder, social phobia, social anxiety disorder, urinary incontinence, anorexia, bulimia nervosa, obesity, ischemia, head injury, calcium overload in brain cells, drug dependence, and / or premature ejaculation are described.
Owner:ACADIA PHARMA INC
Coloured organic electrophoretic particles
The present invention relates to the preparation and use of (colored) organic particles carrying electric charge as electrophoretic (image) displaying particles, to electrophoretic dispersions comprising the organic particles carrying electric charge, electrophoretic (image) devices (especially displays) comprising the colored organic particles carrying electric charge, to the novel functionalized particles, and to their use. The particles are obtainable according to a method represented by the reaction scheme as given in FIG. 1.
Owner:BASF AG
Sodium channel modulators
Owner:THERAVANCE BIOPHARMA R&D IP LLC
Branched chain-containing aromatic compound
ActiveUS20120059149A1Easy to operatePeptide/protein ingredientsCarboxylic acid amides preparationOperabilityCrystallization
Owner:AJINOMOTO CO INC
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