Relieving depression powder oral preparation and preparation thereof
An oral preparation and preparation technology are applied in the field of oral preparations in which extracts are active ingredients of medicines, and can solve the problems of large dosage of traditional Chinese medicine decoctions, inability to commercialize, and inconvenient to carry and take.
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Embodiment 1
[0046] Embodiment one: "Kaiyusan" extract 1 (extract and volatile oil) preparation method
[0047] Prescription: 15 grams of white peony root, 6 grams of angelica, 9 grams of white mustard seed, 3 grams of Bupleurum, 3 grams of roasted licorice, 6 grams of scorpion, 9 grams of Atractylodes macrocephala, 9 grams of Poria cocos, 6 grams of turmeric, 9 grams of Cyperus cyperus, 9 grams of geranium
[0048] Preparation method: cleanly select the medicinal materials of the prescription, weigh each medicinal material according to the prescription amount, add 6-15 times the amount of water to soak for 2-10 hours, heat and boil for 2-3 times, combine the extracts, collect volatile oil; water extraction The liquid was left to stand for 12-48 hours, filtered to get the supernatant, and concentrated under reduced pressure to obtain a medicinal extract of about 15.4 g of water extract and about 0.3 g of volatile oil.
Embodiment 2
[0049] Embodiment two: "Kaiyusan" extract 2 (dry powder and volatile oil) preparation method
[0050] Prescription: white peony root 15g angelica 6g white mustard seed 9g Bupleurum 3g licorice 2.4g scorpion 6g atractylodes 9g Poria 9g turmeric 6g Cyperus 9g geranium 9g
[0051] Preparation method: cleanly select the medicinal materials of the prescription, weigh each medicinal material according to the prescription amount, add 8-10 times the amount of water to soak for 2-8 hours, heat to boiling and extract 2-3 times, combine the extracts, collect volatile oil; water extraction The liquid was left to stand for 12-48 hours, filtered to take the supernatant, concentrated under reduced pressure, and spray-dried to obtain a dry powder of about 14.8g of water extract; about 0.15g of volatile oil.
Embodiment 3
[0052] Embodiment three: "Kaiyu San" oral solid preparation preparation method
[0053] (1) Preparation of "Kaiyu San" Granules
[0054] prescription:
[0055] "Kaiyusan" extract 1 10-90%
[0056] Starch 5.0-70%
[0057] Dextrin 2.0-20%
[0058] Xylitol 5.0-20%
[0059] Methyl sorbate 0.001-2.0%
[0060] Preferred Prescription:
[0061] "Kaiyusan" extract 1 15.4g
[0062] Starch 3.0g
[0063] Dextrin 3.0g
[0064] Xylitol 2.0g
[0065] Methyl sorbate 0.002g
[0066] Preparation method: prepare the extract of "Kaiyu San" according to the method in Example 1, add the prescribed amount of auxiliary materials to make granules according to the conventional method, dissolve the volatile oil with an appropriate amount of ethanol, spray evenly on the granules, dry at low temperature, and pack to make Two bags, each bag 11.7g.
[0067] (2) Preparation of "Kaiyu San" tablet:
[0068] (1) Ordinary tablet prescription:
[0069] "Kaiyusan" extract 2 5.0-90%
[0070] Starch...
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