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Relieving depression powder oral preparation and preparation thereof

An oral preparation and preparation technology are applied in the field of oral preparations in which extracts are active ingredients of medicines, and can solve the problems of large dosage of traditional Chinese medicine decoctions, inability to commercialize, and inconvenient to carry and take.

Inactive Publication Date: 2008-08-13
张文芳
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0015] The ancient "Kaiyu San" only has decoction, which needs to be decocted and taken after purchasing decoction pieces. It is very inconvenient to carry and take it. After research, we have made modern oral preparations of traditional Chinese medicine through quantitative control of index components. The product dosage is accurate and the quality is stable. It is convenient to take and is suitable for large-scale commercial production. It overcomes the shortcomings of traditional Chinese medicine decoctions such as large dosage, inaccurate dosage, inconvenient carrying and taking, and inability to commercialize. It is convenient for clinical treatment and home use.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] Embodiment one: "Kaiyusan" extract 1 (extract and volatile oil) preparation method

[0047] Prescription: 15 grams of white peony root, 6 grams of angelica, 9 grams of white mustard seed, 3 grams of Bupleurum, 3 grams of roasted licorice, 6 grams of scorpion, 9 grams of Atractylodes macrocephala, 9 grams of Poria cocos, 6 grams of turmeric, 9 grams of Cyperus cyperus, 9 grams of geranium

[0048] Preparation method: cleanly select the medicinal materials of the prescription, weigh each medicinal material according to the prescription amount, add 6-15 times the amount of water to soak for 2-10 hours, heat and boil for 2-3 times, combine the extracts, collect volatile oil; water extraction The liquid was left to stand for 12-48 hours, filtered to get the supernatant, and concentrated under reduced pressure to obtain a medicinal extract of about 15.4 g of water extract and about 0.3 g of volatile oil.

Embodiment 2

[0049] Embodiment two: "Kaiyusan" extract 2 (dry powder and volatile oil) preparation method

[0050] Prescription: white peony root 15g angelica 6g white mustard seed 9g Bupleurum 3g licorice 2.4g scorpion 6g atractylodes 9g Poria 9g turmeric 6g Cyperus 9g geranium 9g

[0051] Preparation method: cleanly select the medicinal materials of the prescription, weigh each medicinal material according to the prescription amount, add 8-10 times the amount of water to soak for 2-8 hours, heat to boiling and extract 2-3 times, combine the extracts, collect volatile oil; water extraction The liquid was left to stand for 12-48 hours, filtered to take the supernatant, concentrated under reduced pressure, and spray-dried to obtain a dry powder of about 14.8g of water extract; about 0.15g of volatile oil.

Embodiment 3

[0052] Embodiment three: "Kaiyu San" oral solid preparation preparation method

[0053] (1) Preparation of "Kaiyu San" Granules

[0054] prescription:

[0055] "Kaiyusan" extract 1 10-90%

[0056] Starch 5.0-70%

[0057] Dextrin 2.0-20%

[0058] Xylitol 5.0-20%

[0059] Methyl sorbate 0.001-2.0%

[0060] Preferred Prescription:

[0061] "Kaiyusan" extract 1 15.4g

[0062] Starch 3.0g

[0063] Dextrin 3.0g

[0064] Xylitol 2.0g

[0065] Methyl sorbate 0.002g

[0066] Preparation method: prepare the extract of "Kaiyu San" according to the method in Example 1, add the prescribed amount of auxiliary materials to make granules according to the conventional method, dissolve the volatile oil with an appropriate amount of ethanol, spray evenly on the granules, dry at low temperature, and pack to make Two bags, each bag 11.7g.

[0067] (2) Preparation of "Kaiyu San" tablet:

[0068] (1) Ordinary tablet prescription:

[0069] "Kaiyusan" extract 2 5.0-90%

[0070] Starch...

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PUM

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Abstract

The present invention relates to a kaiyusan oral medicine liquid preparation and a method for preparing the same, which is prepared from 11 Chinese traditional medicines mixed extract (including water extract or volatile oil, extractum or dry powder): white paeony root, angelica, white mustard, bupleurum, baked licorice, scorpion, large head atractylodes rhizome, tuckahoe, curcuma, cyperus rotundus l, tiankui grass as raw materials, and acceptable carrier or excipient as substrate in medicine by conventional process. The preparation has effects of relieving liver qi stagnation, reducing phlegm and resolving masses, and is main used for treating mammary lump and mammary tuberculosis.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to an oral preparation for mainly treating breast addiction and tuberculosis and a preparation method thereof, in particular to an oral preparation which takes the extract of Kaiyu San traditional Chinese medicine prescription as the active ingredient of the medicine. Background technique [0002] "Kaiyu San" was created by (Qing) Chen Shiduo's "Surgical Secret Records". It has always been used as a common prescription for breast addiction and tuberculosis. Poria cocos, turmeric, Cyperus cyperi, and geranium have the effects of soothing the liver and relieving stagnation, resolving phlegm and dispelling stagnation, and are mainly used to treat breast addiction and tuberculosis syndrome. [0003] The sources of Chinese medicinal materials of "Kaiyu San" are as follows: [0004] Radix Paeoniae Alba: It is the root of Paeoniae officinalis, a plant of Ranunculaceae, which ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61K9/48A61K9/20A61K9/46A61K9/28A61K9/16A61K9/10A61K47/38A61K47/40A61K47/36A61K47/46A61K47/26A61P11/10A61P15/00A61P1/16A61K35/64
Inventor 张文芳曹世栋
Owner 张文芳
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