Medicinal composition for treating angioneurotic headache and preparation thereof

A composition and neurological technology, applied in the directions of drug combination, drug delivery, pharmaceutical formulation, etc., can solve the problems of tissue blood stasis, involving pain-sensing nerve fibers, the pain relief effect is not very obvious and continuous, and the curative effect is fluctuating and unstable.

Active Publication Date: 2008-09-10
TONGJI HOSPITAL ATTACHED TO TONGJI MEDICAL COLLEGE HUAZHONG SCI TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Angioneurotic headache is caused by cerebral vasospasm contraction and dilation causing changes and obstacles in blood flow, causing blood stasis in nearby tissues, and involving pain nerve fibers. Traditional Chinese medicine believes that it is appropriate to use blood circulation to remove stasis and two-way regulation of cerebral vascular contraction and relaxation. It is difficult for ordinary western medicine to achieve such effects by dredging collaterals, relieving pain, calming the nerves, etc.
Although there are also some Chinese patent medicines for the treatment of vascular neuropathic headaches, such as Chuanxiong Tea Tiaosan, Zhengtian Pills, Compound Yangjiao Granules, etc., some of these Chinese patent medicines have not very obvious and sustained analgesic effects, and some of them promote blood circulation and remove blood stasis, and bidirectionally regulate brain pain. The functions of vasoconstriction and relaxation are not good, and some curative effects fluctuate unstable, resulting in repeated attacks of pain in patients, and they still have to rely on some western medicines to maintain

Method used

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  • Medicinal composition for treating angioneurotic headache and preparation thereof
  • Medicinal composition for treating angioneurotic headache and preparation thereof
  • Medicinal composition for treating angioneurotic headache and preparation thereof

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Effect test

Embodiment 1

[0024] The pharmaceutical composition for the treatment of angioneurotic headache of the present invention is composed of Rhizoma Chuanxiong 300g, Angelica 240g, Salvia miltiorrhiza 400g, Radix Paeoniae Rubra 240g, Corydalis Corydalis (made with vinegar) 300g, Vitex 200g, Tribulus terrestris (stir-fried) 240g, Cassia chinensis 600g , Angelica dahurica 200g prepared medicament.

Embodiment 2

[0026] The pharmaceutical composition for the treatment of angioneurotic headache of the present invention is composed of Rhizoma Chuanxiong 350g, Angelica 270g, Salvia miltiorrhiza 420g, Radix Paeoniae Rubra 280g, Corydalis Corydalis (made with vinegar) 350g, Vitex 250g, Tribulus terrestris (stir-fried) 260g, Cassia chinensis 650g , Angelica dahurica 150g prepared medicament.

Embodiment 3

[0028] The pharmaceutical composition for the treatment of angioneurotic headache of the present invention is composed of Rhizoma Chuanxiong 250g, Angelica 200g, Salvia miltiorrhiza 350g, Radix Paeoniae Rubra 200g, Corydalis Corydalis (made with vinegar) 250g, Vitex 150g, Tribulus terrestris (stir-fried) 200g, and Cassia japonica 500g , Angelica dahurica 150g prepared medicament.

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Abstract

The invention relates to a medicine combination used for treating angioneurotic headache and a preparation method thereof. The medicine combination is proportionally made of hemlock parsley, angelica sinensis, Salvia, red peony root, Rhizoma Corydalis, ructus Viticis, caltrop, abalone shell and angelica. The method of the invention is that: 1) the fumitory is smashed or effective substance is extracted to obtain the composition a; 2) the volatile oil of hemlock parsley, angelica, angelica dahurica is extracted by distillation to obtain the composition b; distillated water solution is reserved to obtain the composition c; after being distillated, the residue of raw materials is reserved to obtain the composition d; 3) the salvia miltiorrhiza is smashed or the effective substance is extracted to obtain the composition e; 4) the red peony root, the Fructus Viticis, the caltrop and the abalone shell are mixed with the composition d and decocted or extracted by ethanol to obtain the composition f; 5) the composition c and the composition f are combined to be condensed into thick paste; 6) and the composition a and the composition e are added into the thick paste. With or without proper auxiliary materials being added, formulation acceptable by the clinical treatment is made. The medicine combination can regulated the contraction and the relaxation of cerebral vasospasm in bidirectional way and has significant curative effect on the angioneurotic headache.

Description

technical field [0001] The invention relates to a drug for promoting blood circulation, removing stasis, dredging collaterals and relieving pain prepared from Chinese herbal medicines, in particular to a pharmaceutical composition for treating angioneurotic headache and a preparation method of the pharmaceutical composition. Background technique [0002] According to the results of the first national drug safety survey by the China Non-prescription Drug Association: 69% of urban residents have experienced headaches, and the incidence of headaches among people under the age of 30 and those aged 30 to 45 exceeds 70%, and the proportion of headaches in all age groups exceeds half. , Headache has become one of the four major culprits affecting people aged 30 to 50. Headache is a common phenomenon of human beings all over the world. According to the statistics of the National Headache Foundation of the United States, at least 45 million Americans suffer from chronic headaches or ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/85A61K9/20A61K9/48A61K9/14A61K9/16A61K9/10A61K9/08A61K9/00A61P25/04A61K35/56A61K35/618
Inventor 黄光英方建国王荔芳汤杰王开富徐丽君王文清杨明炜王池卿
Owner TONGJI HOSPITAL ATTACHED TO TONGJI MEDICAL COLLEGE HUAZHONG SCI TECH
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