The invention relates to a drug for treating long-standing headache and a preparation method thereof. The drug contains the following raw materials based on the parts by weight: 40-60 of huangteng, 20The invention relates to a drug for treating long-standing headache and a preparation method thereof. The drug contains the following raw materials based on the parts by weight: 40-60 of huangteng, 20depression, and the like, does not belong to a pain killer or pain reliever, is special for treating headache and has no toxic and side effects and sequela.r depression, and the like, does not belong to a pain killer or pain reliever, is special for treating headache and has no toxic and side effects and sequela.-30 of radix bupleuri, 20-30 of Cimicifuga foetida, 25-35 of rhizoma ligustici wallichii, 20-30 of perilla, 10-20 of peony, 20-30 of angelica dahurica, 10-20 of wilson yarrow herb, 20-30 of caulis per-30 of radix bupleuri, 20-30 of Cimicifuga foetida, 25-35 of rhizoma ligustici wallichii, 20-30 of perilla, 10-20 of peony, 20-30 of angelica dahurica, 10-20 of wilson yarrow herb, 20-30 of caulis perllae, 10-20 of radices puerarire, 20-30 of smilax lanceifolia, 10-20 of galangal, 10-20 of herba Schizonepetae, 20-30 of rhizoma gastrodiae, 10-20 of camphor wood and 10-20 of chrysanthemum. The drugllae, 10-20 of radices puerarire, 20-30 of smilax lanceifolia, 10-20 of galangal, 10-20 of herba Schizonepetae, 20-30 of rhizoma gastrodiae, 10-20 of camphor wood and 10-20 of chrysanthemum. The drugmainly treats long-standing headache, chronic headache, noncausal headache, ache of back side of head, hemicrania, headache caused by anemofrigid cold, malarial headache, headache caused by asthenopiamainly treats long-standing headache, chronic headache, noncausal headache, ache of back side of head, hemicrania, headache caused by anemofrigid cold, malarial headache, headache caused by asthenopia, headache caused by heat sensation in chest, palmes and soles, headache caused by stagnation in liver channel, qi stagnation and impairment of spleen by anxiety, headache caused by overmuch stay-up o, headache caused by heat sensation in chest, palmes and soles, headache caused by stagnation in liver channel, qi stagnation and impairment of spleen by anxiety, headache caused by overmuch stay-up or