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Oral preparation of 'chaihu dayuan' decoction

A technology of oral preparation and Bupleurum, applied in the field of medicine, can solve the problems of inaccurate dosage, large dosage of traditional Chinese medicine decoction, and inability to commercialize it.

Inactive Publication Date: 2008-09-17
BEIJING JINFANGHUA MEDICAL SCI TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0014] The ancient Chaihuda original drink did not only have a decoction. It needs to be decocted and taken after purchasing the decoction pieces. It is very inconvenient to carry and take it. After research, we have made a modern oral preparation of traditional Chinese medicine through quantitative control of the index components. The product dosage is accurate, the quality is stable, and it is convenient. It is suitable for large-scale commercial production, and overcomes the shortcomings of traditional Chinese medicine decoctions such as large dosage, inaccurate dosage, inconvenient carrying and taking, and inability to commercialize, and is convenient for clinical treatment and home use.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0048] Example 1: Preparation method of Chaihuda original drink extract 1 (extract and volatile oil)

[0049] Prescription: 4.5 grams of Bupleurum, 4.5 grams of raw Citrus aurantium, 4.5 grams of Chuanpu, 4.5 grams of Qingpi, 2.1 grams of Zhigancao, 4.5 grams of Scutellaria, 3 grams of Bellflower, 1.8 grams of Caoguo, 6 grams of betel nut, and 10 grams of lotus leaf stem

[0050] Preparation method: cleanly select various medicinal materials for the prescription, weigh each medicinal material according to the prescription amount, add 6 to 15 times the amount of water to soak for 2-10 hours, heat and slightly boil for extraction 2-3 times, combine the extracts, collect volatile oil; water extraction The liquid was left to stand for 12-48 hours, filtered to get the supernatant, and concentrated under reduced pressure to obtain the extract as about 12.5 g of water extract and about 0.1 g of volatile oil.

Embodiment 2

[0051] Embodiment Erchaihuda original drink extract 2 (dry powder and volatile oil) preparation method

[0052] Prescription: Bupleurum, Raw Citrus aurantium, Chuanpu, Qingpi, Scutellaria baicalensis 5 grams each, Platycodon grandiflorum 3 grams, Caoguo 2 grams, Betel nut 6 grams, Lotus leaf stem 5 grams, Zhigancao 2 grams

[0053] Preparation method: cleanly select the medicinal materials of the prescription, weigh each medicinal material according to the prescription amount, add 8 to 10 times the amount of water to soak for 2-8 hours, heat to boiling and extract 2-3 times, combine the extracts, collect volatile oil; water extraction The liquid was left to stand for 12-48 hours, the supernatant was collected by filtration, concentrated under reduced pressure, and spray-dried to obtain a dry powder of about 10.2 g of water extract; about 0.1 g of volatile oil.

Embodiment 3

[0054] Example 3: Preparation method of oral solid preparation of Chaihuda Yuanyin

[0055] (1) Preparation of Chaihuda Yuanyin Granules

[0056] prescription:

[0057] Chai Huda Original Drink Extract 1 10-90%

[0058] Starch 5.0-70%

[0059] Dextrin 2.0-20%

[0060] Xylitol 5.0-20%

[0061] Methyl sorbate 0.001-2.0%

[0062] Preferred Prescription:

[0063] Chaihuda Original Drink Extract 1 12.6g

[0064] Starch 3.0g

[0065] Dextrin 5.0g

[0066] Xylitol 2.0g

[0067] Methyl sorbate 0.002g

[0068] Preparation method: Prepare Chai Chaihuda original drink extract according to the method in Example 1, add the prescribed amount of auxiliary materials to make granules according to the conventional method, dissolve the volatile oil with an appropriate amount of ethanol, spray evenly on the granules, dry at low temperature, and pack.

[0069] (2) Prepare the original decoction tablets of Chaihuda:

[0070] (1) Ordinary tablet prescription:

[0071] Chai Huda Origin...

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Abstract

The invention relates to an oral preparation, which is characterized in that a mixing extraction (extract or dry powder and volatile oil) of bupleurum, raw orange fruit, magnolia obavata, dried green orange peel, astragalus root, root of the balloonflower, Tsaoko Fruit, betel-nut, lotus petiole and liquorice root; a carrier or an excipient are used as substrate, which can be accepted in pharmacy; the oral preparation is prepared with the extraction and the substrate in ordinary craft; the preparation has wetness and sputum eliminating effect, and treats wet weight, heat siltation and block original membrane disease; the long clinical application of the prescription has the advantages of good therapeutic effect for treating influenza fever patient.

Description

technical field [0001] The invention belongs to the technical field of medicine, and relates to an oral preparation of a therapeutic drug mainly used for treating phlegm-dampness obstructed by membranes and a preparation method thereof, in particular to an extract of a traditional Chinese medicine formula of Bupleurum Dayuan Decoction as an active ingredient of the medicine, and has antimalarial, antimalarial, Oral preparation against the action of influenza virus. Background technique [0002] "Chaihu Dayuan Drink" was created by Yu Gen of the Qing Dynasty in "Rebooking the Popular Treatise on Febrile Diseases". , composed of astragalus, bellflower, grass fruit, betel nut, lotus leaf stalk, and roasted licorice, has the effect of dispersing dampness and resolving phlegm, mainly treating dampness heavier than heat, and blocking the original syndrome of membrane. The long-term clinical application of this prescription has shown that it has a good curative effect on dampness ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9064A61K9/00A61K9/16A61K9/14A61K9/20A61K9/48A61K47/20A61K47/34A61K47/36A61K47/40A61K47/44A61P31/16A61P33/06A61K47/10A61K47/26A61K47/32
Inventor 张文芳
Owner BEIJING JINFANGHUA MEDICAL SCI TECH
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