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Uses and preparations of common camptotheca fruit glycosides of common camptotheca fruit extract

A technology of higoside and extract, which is applied in the field of use and preparation of higoside in camptotheca fruit extract, and can solve the problem of no medicinal use of higoside and the like

Active Publication Date: 2008-12-03
JIANGSU KANION PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] There are no other reports about the medicinal use of citrus in the prior art

Method used

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  • Uses and preparations of common camptotheca fruit glycosides of common camptotheca fruit extract
  • Uses and preparations of common camptotheca fruit glycosides of common camptotheca fruit extract
  • Uses and preparations of common camptotheca fruit glycosides of common camptotheca fruit extract

Examples

Experimental program
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Effect test

Embodiment 1

[0160] Example 1. A kind of citrus glycoside preparation, take the citrus glycoside prepared by the prior art technology, add the drug carrier, make a tablet, be used as antibacterial or antiviral or anti-high fever or anti-inflammatory or analgesic medicine, or be used for sensitive Treatment of infectious diseases caused by bacteria, viruses or leptospirosis.

Embodiment 2

[0161] Example 2. A kind of citrus glycoside preparation, take the citrus glycoside prepared by the prior art process, add the drug carrier, make the granule, be used as antibacterial or antiviral or anti-high fever or anti-inflammation or analgesic medicine, or be used for sensitive Treatment of infectious diseases caused by bacteria, viruses or leptospirosis.

Embodiment 3

[0162] Example 3. A kind of citrus glycoside preparation, take the citrus glycoside prepared by the prior art process, add the drug carrier, make capsules, be used as antibacterial or antiviral or anti-high fever or anti-inflammatory or analgesic medicine, or be used for sensitive Treatment of infectious diseases caused by bacteria, viruses or leptospirosis.

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Abstract

The invention discloses an application of vincoside lactam extracted from common camptotheca fruit in preparation of antibacterial or antiviral or anti-hyperthermia or anti-inflammatory or pain relieving drugs or in preparation of drugs for treating infectious diseases caused by sensitized bacteria and viruses or leptospirosis. The diseases caused by sensitized bacteria and viruses comprise: acute tonsillitis, faucitis, upper respiratory tract infections, bronchitis, otitis media pneumonia, conjunctivitis, hordeolum, periodontal abscess, burn wound infections, urinary tract infections, and infections caused during after-surgery prevention. The invention also discloses a vincoside-lactam preparation with the application.

Description

technical field [0001] The invention relates to a medical use of a traditional Chinese medicine extract, in particular to a medical use of citrus citrus extract. The present invention also relates to the citrus glycoside preparation for this purpose. Background technique [0002] Higoside, Chinese name: Higoside, Vinblastam; English name: Vincoside-lactam, VCS-LT, structural formula: [0003] [0004] Since Wall et al. first isolated camptothecin from camptothecin in 1966 and found that it had significant anticancer activity, more than 20 chemical components have been isolated from it, including camp-tothecine (CPT), 10 -Hydroxycamptothecin, 11-hydroxycamptothecin, 10-methoxycamptothecin, camptothecin, betulinic acid, vincoside-lactam (VCS-LT) and the like. Artificial synthesis has also made gratifying progress. Studies have found that citrus citrus glycosides are significantly higher than camptothecin and other analogues. [0005] Camptothecin (CPT) and citrusin (VCS...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/706A61K47/02A61K47/10A61K47/16A61K47/20A61P1/02A61P11/00A61P11/04A61P13/00A61P17/02A61P27/16A61P31/00A61P31/04A61P31/12A61P29/00C07H1/08
CPCY02A50/30
Inventor 肖伟戴翔翎凌娅丁岗王振中李明慧曹亮
Owner JIANGSU KANION PHARMA CO LTD
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