Chinese medicinal composition for treating osteoporosis and preparation method thereof
A technology for osteoporosis and composition, applied in the field of pharmaceutical preparations, can solve the problems of blood stasis, blood deficiency, generation speed and activity impact of osteoporosis, and inability to supplement calcium minerals in osteoporosis, so as to improve calcium Effects of ion uptake ability, maintenance of bone strength and bone biomechanical properties in rats
Active Publication Date: 2010-08-25
SOUTHERN MEDICAL UNIVERSITY
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Problems solved by technology
In summary, although the existing Guling Pills and Guling Tablets have certain curative effects on osteoporosis, there are still the following deficiencies: 1. The activity of osteoclasts in aging bones is greater than that of osteoblasts, causing bone calcium loss , the bone remodeling is out of balance, and it is in a state of negative balance. These bone minerals mainly rely on exogenous supplements, while simple "kidney-tonifying" Chinese medicines cannot supplement calcium and other essential minerals for human bones, which affects bone mineralization; "Kidney-tonifying" traditional Chinese medicine cannot solve the problems of blood stasis and blood deficiency in osteoporosis, and the production speed and activity of bone metabolism regulatory factors such as TGF-β1 and IGF-1 will be affected
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Abstract
The invention provides a Chinese medicine combination used for treating osteoporosis; the Chinese medicine combination is composed of active ingredients and pharmaceutically acceptable excipients and is characterized in that: the active ingredients are prepared by the raw medicines with the following parts by weight: 4-12 parts of rhizoma drynariae, 4-12 parts of deerhorn gelatin, 0.5-2 parts of hairy deerhorn, 4-12 parts of common dodder, 4-12 parts of nacre, and 4-12 parts of caulis spatholobi. The Chinese medicine combination of the invention is obtained by modifying GuLing tablets; on thebasis of medicinal material for tonifying the kidneys such as rhizoma drynariae, deerhorn gelatin, hairy deerhorn and common dodder, the Chinese medicine combination is added with the medicinal materials for calcium supplement like nacre as well as the medicinal materials for activating blood circulation and dredging collaterals like caulis spatholobi, thus achieving good curative effect on osteoporosis.
Description
technical field The invention relates to a medicine preparation, in particular to a traditional Chinese medicine preparation. Background technique Osteoporosis (OP) is a skeletal disease characterized by decreased bone mass and microstructural deterioration of bone tissue, leading to weakened bone strength and increased incidence of fractures. Fracture is the most common and serious complication of osteoporosis, and it often occurs in the hip, distal radius, and spine. It not only seriously affects the health and quality of life of the elderly, but also causes disability and death for the elderly. One of the main reasons. According to the population forecast, by 2000 and 2050, the elderly over 60 years old will account for 11% and 20% respectively. my country will enter an aging society, and the number of patients with primary OP will increase dramatically. According to survey statistics, the incidence rate of women (OP) increases from 20% to 80% after 50 years old to 80 y...
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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/486A61P19/10A61K35/32A61K35/56A61K35/618
Inventor 李娟
Owner SOUTHERN MEDICAL UNIVERSITY
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