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Medical composition containing dandelion extract as well as novel application and preparation method thereof

A technology of dandelion extract and composition, which is applied in the field of pharmaceutical composition containing dandelion extract and its new use and preparation, and can solve the problems of complex interaction of components and the like

Active Publication Date: 2010-06-02
CHENGDU BRILLIANT PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the above-mentioned preparations have certain effects, their curative effect and safety still need to be further improved and confirmed. In addition, more complex formulations may need to consider whether the source of raw materials is easy to obtain and the difficulty of quality control, and there may be potential unknown components. complex interplay between

Method used

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  • Medical composition containing dandelion extract as well as novel application and preparation method thereof
  • Medical composition containing dandelion extract as well as novel application and preparation method thereof
  • Medical composition containing dandelion extract as well as novel application and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

preparation Embodiment 1

[0028] Preparation Example 1 :Preparation of dandelion extract

[0029] Take 1kg of clean and appropriately crushed dried dandelion medicinal material, place it in a round bottom flask, add 8L of 70% ethanol containing 5% formic acid, heat and reflux for 1.5 hours, filter, and retain the filtrate; 6L of the above-mentioned medicinal residue contains 5% For the second extraction with 70% ethanol of formic acid, reflux for 1 hour, filter, and combine the two filtrates. The filtrate is concentrated under reduced pressure to dryness, dried and crushed to obtain 150 g to 200 g of dandelion extract A (powder), which is equivalent to 15% to 20% of the original drug amount.

preparation Embodiment 2

[0030] Preparation Example 2 :Preparation of dandelion extract

[0031] Take 1kg of dry dandelion medicinal materials that are cleanly selected and appropriately crushed, and place them in a round-bottomed flask, add 8L of 70% alcohol containing 5% formic acid, and ultrasonically extract for 1 hour at room temperature, filter, and retain the filtrate; % Formic acid and 70% alcohol for the second extraction, ultrasonic extraction for 0.5 hours, filtration, and the two filtrates were combined. The filtrate is thinly evaporated and concentrated to dryness, dried, and pulverized to obtain 100 g to 140 g of dandelion extract B (powder), which is equivalent to 10% to 14% of the original drug amount.

preparation Embodiment 3

[0032] Preparation Example 3 :Preparation of dandelion extract

[0033] Except that 90% alcohol was used as the extraction solvent, the rest was prepared in exactly the same way as in Preparation Example 1 to prepare 80 g to 120 g of dandelion extract C (powder), which is equivalent to 8% to 12% of the original drug amount.

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Abstract

The invention relates to the application of dandelion extract in preparing a medical composition for preventing and treating asthenopia syndrome, the medical composition containing dandelion extract and a method for preparing the containing dandelion extract. The invention further discloses a variety of ophthalmic medical preparations containing dandelion extract for preventing and treating asthenopia syndrome.

Description

Technical field [0001] The present invention relates to the use of a dandelion extract in the preparation of a pharmaceutical composition for the prevention and treatment of asthenopia syndrome, a pharmaceutical composition containing the dandelion extract, and a method for preparing the dandelion extract. The present invention also particularly A variety of ophthalmic pharmaceutical preparations containing the dandelion extract for the prevention and treatment of asthenopia syndrome are disclosed. Background technique [0002] In recent years, due to changes in the social environment, the acceleration of work rhythms, the popularity of video terminals, and the gradual increase in close and fine eye work, the incidence of asthenopia syndrome is increasing. [0003] Asthenopia, also known as eye fatigue, is a common type of disease in ophthalmology at present. It is a syndrome based on the patient's conscious eye symptoms, eye or systemic organic factors and mental (psychological) f...

Claims

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Application Information

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IPC IPC(8): A61K36/288A61K36/482A61K36/45A61K36/56A61K36/42A61K36/605A61K36/68A61K38/39A61K9/06A61K9/107A61K9/127A61K9/70A61K9/00A61P27/02A61K31/728A61K31/045A61K31/185A61K31/375A61K35/413A61K35/56A61K33/30A61K33/22A61K35/618
Inventor 王凌蒋学华宋萍萍
Owner CHENGDU BRILLIANT PHARMA CO LTD
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