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Application of medicinal composition in preparation of autoimmune disease treatment medicaments

An autoimmune disease and composition technology, which is applied in the field of medicine and can solve problems such as traditional Chinese medicine for which autoimmune diseases have not yet been discovered

Inactive Publication Date: 2010-11-17
GUANGZHOU WANGLAOJI PHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0012] At present, the treatment of autoimmune diseases is mostly chemical drugs, and no traditional Chinese medicine has been found to treat autoimmune diseases

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0069] a. Take prescription 1: 36g of honeysuckle, 36g of skullcap, 36g of Nepeta, 36g of gardenia (fried), 36g of forsythia, 36g of Scrophulariaceae, 22g of silkworm (made from ginger), 55g of rehmannia glutinosa, 11g of shegan, 22g of bellflower, 22g of mint , cicada slough 22g, Fangfeng 22g, licorice 11g for spare;

[0070] b. Extraction of extract I: take Scutellaria baicalensis and add 12 times the amount of ethanol to reflux 3 times, each time for 3 hours, the concentration of ethanol is 95%, recover ethanol, concentrate to a relative density of 1.03 to 1.35 at 85 ° C, and obtain extract I ;

[0071] Extraction of extract II: ① Extract volatile oil: take honeysuckle, nepeta, peppermint, and Fangfeng four herbs, combine them together, add 12 times the amount of water, soak for 5 hours, use steam distillation for 8 hours, collect the volatile oil and store it in another device. Continue to extract the medicinal dregs; ②Extraction: The remaining medicinal materials, the me...

Embodiment 2

[0075] a. Take prescription 2: 145g honeysuckle, 145g skullcap, 145g nepeta, 145g gardenia (fried), 145g forsythia, 145g scrophulariae, 85g silkworm (made from ginger), 215g rehmannia, 45g shegan, 85g platycodon, 85g mint , cicada slough 85g, Fangfeng 85g, licorice 45g for spare;

[0076] b. Extraction of extract I: Take Scutellaria baicalensis and add 1 times the amount of ethanol to reflux once, extract for 1 hour, the concentration of ethanol is 30%, recover ethanol, concentrate to a relative density of 1.03-1.35 at 40°C, and obtain extract I;

[0077] Extraction of extract II: ①Extract volatile oil: take honeysuckle, nepeta, peppermint, and Fangfeng four medicinal materials, combine them together, add 1 times the amount of water, soak for 0.5 hours, use steam distillation for 1 hour, collect volatile oil and store it in another container. Continue to extract the dregs; ②Extraction: Add water to decoct the rest of the medicinal materials, the dregs of Scutellaria baicalensi...

Embodiment 3

[0081] a. Take prescription three: 145g honeysuckle, 45g skullcap, 36g nepeta, 36g gardenia (fried), 145g forsythia, 36g scrophulariae, 22g silkworm (made from ginger), 55g rehmannia, 11g shegan, 85g platycodon, 85g mint , cicada slough 22g, Fangfeng 85g, licorice 45g for spare;

[0082] b. Extraction of extract I: Take Scutellaria baicalensis and add 12 times the amount of ethanol to reflux once, each time for 3 hours, the concentration of ethanol is 75%, recover ethanol, concentrate to a relative density of 1.08 to 1.15 at 65°C, and obtain extract I ;

[0083] Extraction of extract II: ① Extract volatile oil: take honeysuckle, nepeta, peppermint, and Fangfeng four medicinal materials, combine them together, add 12 times the amount of water, soak for 5 hours, use steam distillation for 2 hours, collect volatile oil and store it in another device. Continue to extract the medicinal dregs; ②Extraction: Add water to decoct the remaining medicinal materials, the medicinal dregs o...

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PUM

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Abstract

The invention discloses the application of a medicinal composition in the preparation of autoimmune disease treatment medicaments, which belongs to the field of medicine. The medicinal composition is prepared from honeysuckle, baical skullcap root, fineleaf schizonepeta herb, fried cape jasmine fruit, fructus forsythiae, figwort root, ginger bombyx batryticatus, rehmannia root, blackberrykiky rhizome, platycodon root, mint, cicada slough, divaricate saposhnikovia root and licorice root. The medicaments prepared from the medicinal composition of the invention have remarkable effect on the following acute diseases: multiple sclerosis, diabetes mellitus, different cardiovascular diseases, autoimmune diseases, and the first change of different cancers.

Description

technical field [0001] The invention relates to the field of medicine, in particular to the application of a pharmaceutical composition in the preparation of medicines for treating autoimmune diseases. Background technique [0002] A disease caused by an autoimmune reaction to a certain degree. The most basic function of the immune system is to recognize itself and identify foreign bodies, so as to protect itself and reject foreign bodies. There may be a variety of antibodies against self-antigens in normal human serum, but their levels are extremely low, which is not enough to destroy self-components and can remove aging and degenerative self-tissues. This is an autoimmune reaction. When this reaction is too strong, leading to severe tissue damage and showing clinical symptoms, it is called autoimmune disease (auto-immune disease). [0003] The autoimmune process usually leads to tissue damage through type III allergy of the Gail and Coombs classification. Self-organizat...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/88A61P37/02A61K35/64A61K35/63
CPCA61K36/534A61K36/484A61K35/642A61K36/538A61K36/35A61K36/634A61K36/744A61K36/539A61K36/804A61K36/24A61K36/808A61K36/238A61K36/88A61P37/00A61P37/02A61K35/64A61K2300/00
Inventor 施少斌陶应泽郑荣波黄晓丹秦春梅
Owner GUANGZHOU WANGLAOJI PHARM CO LTD
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