Medicament for treating breast cancer and preparation method thereof

Abstract

The invention discloses a medicament for treating breast cancer and a preparation method thereof. The medicament comprises medicament effective components which are 3beta-hydroxyl-28- norursol-12 and 17-diene-22-ketone and a medicament which is prepared from a medicinal auxiliary material, wherein the medicament effective components are 1-90 percent by weight, and the medicinal auxiliary material is 10-99 percent. The structural formula of the medicament effective components is shown in the specification. The preparation method comprises the following steps of: (1) pulverizing garden burnet carbon as a medicament raw material, adding carbinol or ethanol, extracting and filtering and concentrating filter liquor to obtain fluid extract; (2) dispersing the fluid extract in the step (1) by water, extracting by chloroform and recovering a solvent of extract liquor to obtain extract; (3) carrying out silica gel column chromatography separation on the extract in the step (2) and sucking and filtering the obtained solid and recrystallizing to obtain the medicament effective components of the compound; and (4) taking the medicament effective components according to the weight proportion and retaining the medicinal auxiliary material for preparing the medicament. The invention has good treatment effect on treating breast cancer and can replace western medicines for oral administration in the postoperative chemotherapy period.

Description

technical field The invention relates to medicine, which is a medicine for treating breast cancer and a preparation method thereof. Background technique Breast cancer is a disease with a high incidence rate. According to preliminary statistics, the incidence rate has gradually increased in the past 10 years. The current treatment methods for breast cancer are drugs and surgery. Most patients need surgical treatment. Chemotherapy after surgical resection of the tumor is a better treatment method. Regardless of drug treatment or drugs taken during chemotherapy after surgery, effective drugs are generally All are western medicines, but the side effects of western medicines are clinically proven to be very obvious. Although there are traditional Chinese medicines for treating breast cancer in the published data, there is no data showing that their curative effect is significant. Therefore, in order to reduce the toxic and side effects of breast cancer patients taking western ...

AI Technical Summary

Problems solved by technology

The current treatment methods for breast cancer are drugs and surgery. Most patients need surgical treatment. Chemotherapy after surgical resection of the tumor is a better treatment method. Regardless of drug treatment or drugs taken during chemotherapy after surgery, effective drugs are generally Both are western medicines, however, the side effects of western medicines have been clinically proven to be very obvious

Although there are traditional Chinese medicines for treating breast cancer in the published data, there is no data showing that their curative effect is significant

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