Horn polypeptide, and separation method and antioxidation application thereof

An antioxidant activity and pharmaceutical technology, applied in the field of medicine, can solve the problems of weak research on the material basis of the effect and the mechanism of action, and achieve the effects of good antioxidant activity, clear amino acid sequence, and small molecular weight of the polypeptide

Active Publication Date: 2012-01-04
NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Although rhino (wide) horn, antelope horn, buffalo horn and other horn medicinal materials have been used for more than a thousand years, due to the particularity of the source, material, and composition of the medicinal materials, the research on the material basis and mechanism of their effects is still relatively weak. Almost zero coverage of active ingredients

Method used

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  • Horn polypeptide, and separation method and antioxidation application thereof
  • Horn polypeptide, and separation method and antioxidation application thereof
  • Horn polypeptide, and separation method and antioxidation application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] (1) Preparation of buffalo horn extract:

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PUM

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Abstract

The invention relates to the technical field of medicines, particularly a horn polypeptide, and a separation method and application thereof. The horn polypeptide has the following sequence structure: Tyr-Glu-Asp-Cys-Thr-Asp-Cys-Gly-Asn. The polypeptide provided by the invention is extracted and separated from buffalo horns. The pharmacological test proves that the polypeptide provided by the invention has favorable antioxidation activity.

Description

technical field [0001] The invention relates to the technical field of medicines, and relates to a class of horn-like polypeptides with antioxidant activity, a separation method and application thereof. This application is a divisional application of 200910233784.1. Background technique [0002] Horn-like animal medicinal materials are an important part of the motherland's medical treasure house, with definite efficacy and outstanding characteristics. The earliest known herbal book in China, "Shen Nong's Materia Medica", has recorded the nature, taste and efficacy of rhinoceros horn (Cornu Rhinoceri Asiatici) and antelope horn (Cornu Saigae Tataricae), and then appeared in "Famous Doctors" in the Han Dynasty. The records of the nature, flavor and efficacy of horn (Cornu Bubali). For thousands of years, rhinoceros horns, antelope horns, buffalo horns and other horn medicinal materials have been indispensable medicines in Chinese medicine, mainly used to treat heat syndrome....

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C07K7/06C07K1/36C07K1/20C07K1/18C07K1/16A61K38/08A61P39/06
Inventor 刘睿段金廒钱大玮唐于平郭建明
Owner NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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