Device and method for delivery of two or more drug agents

Abstract

A computerized electro-mechanical drug delivery device (10) configured to deliver at least one dose of two or more medicaments. The device comprises a control unit (300). An electro-mechanical drive unit (500, 600) is operably coupled to the control unit and a primary reservoir (90) for a first medicament and a secondary reservoir (100) for a fluid agent, e.g. a second medicament. An operator interface (60) is in communication with the control unit (300). A single dispense assembly (200) is configured for fluid communication with the primary (90) and the secondary (100) reservoir. Activation of the operator panel sets a first dose from the primary reservoir and based on the first dose and a therapeutic dose profile (860), the control unit (300) is configured to determine a dose or range of the fluid agent. Alternatively, the control unit determines or calculates a dose or range of a third medicament.

Description

technical field

[0001] This patent application relates to methods and medical devices for delivering at least two drug formulations from separate reservoirs using a device having a programmable dose setting mechanism and a single dispense interface. Such a pharmaceutical formulation may include a first and a second agent. A single dose setting process initiated by the user causes the drug delivery device to calculate a dose of the second drug formulation based on the selected therapeutic dose algorithm. This single dose setting process initiated by the user may also cause the drug delivery device to calculate the dose of the third drug agent based on a (possibly) different selected therapeutic dose algorithm. This algorithm can be selected prior to dose setting, or selected during dose setting.

[0002] The drug formulations may be contained in two or more multi-dose reservoirs, containers or packages, each containing separate (single drug compound) or premixed (co-formulate...

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