76 results about "Dose profile" patented technology

A method for determining a radiation treatment plan for a radiotherapy system providing multiple individual rays of intensity modulated radiation iteratively optimized the fluence of an initial set of such rays by a function that requires knowledge of only the prescribed dose and the dose resulting from the particular ray fluences. In this way, the need to store individual dose distributions of each ray are eliminated.

A stand-alone calculator enables multi energy electron beam treatments with standard single beam electron beam radiotherapy equipment thereby providing improved dose profiles. By employing user defined depth-dose profiles, the calculator may work with a wide variety of existing standard electron beam radiotherapy systems.

An irradiation apparatus for irradiating by scanning a target volume according to a predetermined dose profile with a scanning beam of charged particles forming an irradiation spot on said target volume, said apparatus comprising: a beam generating device,

• • a reference generator for computing, from said predetermined dose profile, through a dynamic inverse control strategy, the time evolution of commanded variables, these variables being the beam current I(t), the spot position settings x(t),y(t) and the scanning speed settings v_x(t), v_y(t),
  • a monitor device having means for detecting at each time (t), the actual spot position as a measured position defined by the values x_m(t),y_m(t) on the target volume,

characterised in that said irradiation apparatus further comprises means for determining the differences e_x(t), e_y(t) between the measured values x_m(t), y_m(t) and the spot position settings x(t) and y(t), and means for applying a correction to the scanning speed settings v_x(t) and v_y(t) depending on said differences e_x(t), e_y(t). The present invention is also related to a monitor for determining beam position in real-time.

A computerized electro-mechanical drug delivery device (10) configured to deliver at least one dose of two or more medicaments. The device comprises a control unit (300). An electro-mechanical drive unit (500, 600) is operably coupled to the control unit and a primary reservoir (90) for a first medicament and a secondary reservoir (100) for a fluid agent, e.g. a second medicament. An operator interface (60) is in communication with the control unit (300). A single dispense assembly (200) is configured for fluid communication with the primary (90) and the secondary (100) reservoir. Activation of the operator panel sets a first dose from the primary reservoir and based on the first dose and a therapeutic dose profile (860), the control unit (300) is configured to determine a dose or range of the fluid agent. Alternatively, the control unit determines or calculates a dose or range of a third medicament.

A method of calculating a dose distribution for a patient for use in a radiation therapy treatment plan. The method includes acquiring an image of a volume within the patient, defining a radiation source, and defining a reference plane oriented between the radiation source and the patient. The method also includes generating a radiation therapy treatment plan, wherein the plan includes a plurality of rays that extend between the radiation source and the patient volume, and calculating a three-dimensional dose volume for the patient volume from the plurality of rays that intersect the reference plane without first having to independently calculate a dose distribution on each of the plurality of rays. The method can also include displaying the three-dimensional dose volume.

The invention relates to the field of heavy ion beam (comprising proton beam) tumor treatment technology, in particular to a heavy ion beam current transverse dosage distribution measuring detector and a two-dimensional imaging method thereof. The detector is mainly characterized by comprising a gas sealing cavity (1) in which an ionization chamber inner core (2) is arranged and a multi-path signal transfer board (3) electrically connected with the ionization chamber inner core (2); the gas sealing cavity (1) consists of a main body framework (1-1), an entrance window (1-2) and an exit window (1-3); the ionization chamber inner core (2) consists of two groups of ionization chamber units, and each ionization chamber unit consists of a signal pole (2-1), an insulating cushion board (2-2) and a high-voltage pole (2-3); and one end of the multi-path signal transfer board (3) is provided with a contact end (3-3) which is inserted into a sealing port (1-5) of the gas sealing cavity (1) and connected with the signal pole (2-1) of the ionization chamber inner core (2), while the other end is provided with a multi-core connector (3-2) which is a signal output port of a beam current profile monitoring detector.

A radiation measuring device having a plurality of sensors configured to generate charges in response to the radiation includes a signal processing device. The signal processing device uses an signal generated by a proton beam irradiation device upon changing of beam energy and causes accumulation values of charges output from the sensors to be separately stored in a main control device for each value of the energy. The main control device calculates depth dose profiles for values of the beam energy from the accumulation values stored in the main control device and representing the charges. The main control device calculates a range of the beam for each of the values of the beam energy from the depth dose profiles, corrects the depth dose profiles for the values of the beam energy using a correction coefficient that depends on the range and sums the corrected depth dose profiles.

An improved radiation dosimeter device in an improved radiation dosimeter system provides a DC analog output voltage that is proportional to the total ionizing dose accumulated as a function of time at the location of the dosimeter in a host spacecraft, so as to operate in a system bus voltage range common to spacecraft systems with the output being compatible with conventional spacecraft analog inputs, while the total dose is measured precisely by continually monitoring the energy deposited in a silicon test mass accumulating charge including charge contribution prior to radiation threshold detection for improved measurement of the total accumulated charge with the dosimeters being daisy-chained and distributed about the spacecraft for providing a spacecraft dose profile about the spacecraft using the improved radiation dosimeter system.

A particle beam treatment device includes an irradiation nozzle which moves a particle beam in a direction which is perpendicular to an advancing direction; a dose monitor which measures the dose of the particle beam; a planning part which sets the irradiation dose applied to a target volume; and a controlling part which controls the irradiation dose applied to a target volume based on irradiation dose set value which is set by a value measured by the dose monitor and the planning part, wherein the planning part stores the absorbed dose distribution data in the depth direction which is prepared in advance using the absorbed dose at the reference depth which is a predetermined position nearer to an incident side of the particle beam than the position of Bragg peak as the reference and calculates the irradiation dose set value using the absorbed dose at the reference depth.

A method and device are designed to deliver intensity-modulated ion beam therapy radiation doses closely conforming to tumors of arbitrary shape, via a series of two-dimensional (2-D) continuous raster scans of a pencil beam, wherein each scan takes no more than about 100 milliseconds to complete. The device includes a fast scanning nozzle for the exit of an ion beam delivery gantry. The fast scanning nozzle has a fast combined-function X-Y steering magnet, and is coupled to a rastering control system capable of adjusting the length of each scan line, continuously varying the beam intensity along each scan line, and executing multiple rescans of a tumor depth layer within a single patient breathing cycle. An in-beam absolute dose and dose profile monitoring system is capable of millimeter-scale position resolution and millisecond-scale feedback to the control system to ensure the safety and efficacy of the treatment implementation.

New techniques for radiotherapy and radiosurgery are provided. In some aspects of the invention, multiple sources of radiation with characteristics that are projected to constructively interfere at a treatment target are provided. In other aspects, hardware directs multiple radiation sources from the same side of a treatment target, and focuses the initiation of substantial interference on a leading structure in the target. In other aspects, refractive models updated by live feedback are used to improve dosage distribution by, among other things, optimizing the number, length, superposition, overlap, angle and nature of radiation beams. In additional aspects, interstitial beacons and radiation path diversion structures are inserted to improve dosage distribution to a target and avoid critical neighboring structures. In particle therapy, regionally actuable external magnetic fields are also provided, to improve dosage accuracy and avoid collateral damage.

The invention relates to a rapid dosage verifying method based on an X-ray imaging flat panel detector, and the method comprises the steps: enabling a radiotherapy device to carry out irradiation according to all irradiation field parameters of a radiotherapy plan before the radiotherapy, and enabling the X-ray imaging flat panel detector to collect two-dimensional X-ray irradiation field images at the same time; converting the two-dimensional X-ray irradiation field images into the two-dimensional plane dosage distribution of a specific equivalent water depth, carrying out the reverse calculation of a two-dimensional plane dosage of an isocenter, and achieving the dosage verification of the radiotherapy plan before radiotherapy through the comparison and evaluation of the two-dimensional plane dosage calculated by a radiotherapy plan system and an actual measured two-dimensional plane dosage. The method irons out the defects that a conventional clinic dosage verification technology consumes a large amount of time and labor and needs to turn the irradiation field angle to zero, alleviates the burden of a clinic medical physic doctor, can achieve the precise and quick verification of dosage, and is high in applicability.

An apparatus and method for measuring three-dimensional radiation dose distributions with high spatial and temporal resolution using a large-volume scintillator. The scintillator converts the radiation dose distribution into a visible light distribution. The visible light is transported to one or more photo-detectors, which measure the light intensity. The light signals are processed to correct for optical artifacts, and the three-dimensional light distribution is reconstructed. The reconstructed light distribution is post-processed to convert light amplitudes to measured radiation doses. The high temporal resolution of the detector makes it possible to observe the evolution of a dynamic dose distribution as it changes over time. Integral dose distributions can be measured by summing the dose over time.

A phantom and film cassette therefor, a composition of high atomic number elements and tissue-equivalent material for a phantom, and an adjustable holder for a phantom. The film cassette comprises sections of tissue-equivalent material, wherein the sections retain a sheet of film when closed together and the phantom composition comprises tissue-equivalent material and high atomic number elements. In operation, dose distributions are determined via computation at various depths within a simulated water-equivalent phantom. After calculating dose distributions, an actual beam is delivered to a phantom containing the cassette, or utilizing a phantom containing high atomic number elements, wherein the phantom mimics human tissue, wherein the phantom houses radiographic film. Images are then generated on the film, the images are converted into an actual dose distribution, and the actual dose distribution is compared with the calculated dose distributions. Finally, a patient is treated based on the beam delivery thus verified.