Drug for treatment of polycystic ovary syndrome (PCOS) and abnormal glucose metabolism coexisting diseases

A polycystic ovary and sugar metabolism technology, applied in the field of fatty acid components and fatty acid raw materials, can solve the problems of endocrine and metabolic disorders and individual differences that cannot be adjusted

Active Publication Date: 2013-06-19
RES INST OF XIAN JIAOTONG UNIV & SUZHOU
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But for inapplicable patients, it can also cause other endocrine and metabolic disorders
Therefore, mixed alternative therapy still has the disadvantage that individual differences cannot be adjusted

Method used

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  • Drug for treatment of polycystic ovary syndrome (PCOS) and abnormal glucose metabolism coexisting diseases
  • Drug for treatment of polycystic ovary syndrome (PCOS) and abnormal glucose metabolism coexisting diseases

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Experimental program
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Embodiment Construction

[0020] In order to facilitate understanding, the present invention will be described in detail below through specific examples. It should be pointed out that these descriptions are only exemplary descriptions and do not limit the scope of the present invention. Many variations and modifications of the present invention will be apparent to those skilled in the art from the discussion of this specification.

[0021] Carry out the clinical observation of 60 cases in order to observe the clinical curative effect of this preparation:

[0022] 1. Clinical observation of polycystic ovary syndrome curative effect standard:

[0023] 1. Basic cure: the symptoms of polycystic ovary syndrome basically disappear, menstruation is normal, ovarian ovulation is normal, (clinical or biochemical) hyperandrogen manifestations are corrected, and insulin resistance is corrected.

[0024] 2. Relief: Symptoms improve, menstruation is regular but sometimes delayed, ovarian ovulation varies. Hyperan...

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Abstract

According to a technical scheme on the first aspect, the invention provides a drug for treatment of polycystic ovary syndrome (PCOS) and abnormal glucose metabolism coexisting diseases. The drug is characterized by including the following four fatty acid components by mass: 17-22% of palmitic acid, 11-23% of hexadecenoic acid, 22-28% of 9-octadecenoic acid, 13-35% of 9, 12, 15-octatecatrienoic acid, and the balance pharmaceutically acceptable additives or excipients. The components are mixed according to compatibility to be prepared into soft capsules and other oral preparations, so that the insulin receptor substrate (IRS) protein level can be effectively reduced so as to inhibit the glucose way, the insulin receptor active time can be increased and the insulin level can be enhanced, and the insulin sensitivity is increased so as to facilitate the reduction of insulin resistance degree. Thus, the drug can have the functions of improving and recuperating ovary ovulatory dysfunction, i.e. PCOS and abnormal glucose metabolism diseases. Compared with other drugs, the drug has simple components, and belongs to highly effective, safety, and simplified drugs.

Description

technical field [0001] The invention relates to a fatty acid composition extracted from natural plants, and a fatty acid raw material drug which is compatible according to the content and composition ratio of the fatty acid composition. In particular, it relates to a medicine for preventing and treating ovarian ovulation dysfunction-polycystic ovary syndrome (PCOS) and abnormal glucose metabolism. Background technique [0002] Ovarian Ovulatory Dysfunction-Polycystic Ovary Syndrome (PCOS) and Abnormal Glucose Metabolism Coexisting Disease is an endocrine and metabolic disorder disease involving many factors such as endocrine, metabolism and genetics. It is characterized by an increase in the number of follicles and hyperfunction, which are the pathological characteristics of the ovary. Insulin resistance is the common pathogenesis of abnormal ovarian function and abnormal glucose metabolism. Its incidence in the affected population accounts for 5% to 10% of women of childb...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/202A61K31/201A61K31/20A61P15/08A61P3/10A61P3/00
Inventor 王和平阮丽娜徐亚梅
Owner RES INST OF XIAN JIAOTONG UNIV & SUZHOU
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