Self-stretching intra-esophageal stent capable of carrying local chemotherapy drugs

A chemotherapeutic drug and self-stretching technology, applied in the field of medical devices, can solve the problems of restricting the clinical application of esophageal stents, difficult to accept stent treatment, affecting the quality of life of patients, etc., to relieve the pain of eating, prevent reflux, and achieve high local concentration. Effect

Inactive Publication Date: 2015-07-01
HENAN UNIV OF SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0002] At present, cancer is one of the three major killers of human diseases, and the mortality rate of patients is relatively high. With the emergence of esophageal cancer, medical methods are also continuously improved. For example, in the treatment of esophageal stenosis caused by malignant tumors, clinicians put in stents to achieve the purpose of expanding the pipeline. Taking esophageal cancer as an example, esophageal cancer is one of the common malignant tumors of the digestive tract in China. It ranks 6th among malignant tumors in the world. Once discovered, most of them are in the middle and late stages. The most common problems in the middle and late stages of esophageal cancer patients are the difficulty in swallowing and eating caused by esophageal stenosis and obstruction in different degrees, which obviously affects the quality of life of patients.
Although the placement of the existing esophageal stent can quickly relieve the patient's difficulty in swallowing and eating, after the existing stent is placed, the stent always tightly supports the esophagus no matter when eating or not, and the patient's foreign body sensation is obvious. Gastric reflux is a major disadvantage, which obviously limits the clinical application of esophageal stents, making it difficult for most patients with esophageal cancer to receive stents.

Method used

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  • Self-stretching intra-esophageal stent capable of carrying local chemotherapy drugs
  • Self-stretching intra-esophageal stent capable of carrying local chemotherapy drugs
  • Self-stretching intra-esophageal stent capable of carrying local chemotherapy drugs

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Embodiment Construction

[0021] As shown in the figure, a self-stretching esophageal stent capable of carrying local chemotherapy drugs includes a top ring 1, a force transmission plate 2, a frame body, and a film cover 3 set outside the frame. The film cover 3 is made of silica gel. The film sleeve, on the one hand, squeezes the cancerous part of the esophagus under the action of the frame, making it easier to eat; on the other hand, it can also prevent tumors from growing inward from the pores of the frame. The outer wall of the film cover 3 is evenly distributed with drug-loaded thin tubes, the drug-loaded thin tubes are thin tubes with micropores, and the drug-loaded thin tubes are loaded with chemotherapeutic drugs, and the chemotherapeutic drugs are 5-fluorouracil One of microspheres, mitomycin C microspheres, doxorubicin microspheres or paclitaxel. The setting density of the drug-loaded thin tube is 1 / 4cm 2 . Wherein, the upper end of the frame body is fixedly connected with the film cove...

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Abstract

The invention relates to a self-stretching intra-esophageal stent capable of carrying local chemotherapy drugs. The self-stretching intra-esophageal stent capable of carrying the local chemotherapy drugs comprises a top ring, actuating plates, a frame body and a film sleeve sleeved outside the frame body, wherein slim drug carrying tubes are evenly distributed on the outer wall of the film sleeve, the chemotherapy drugs are contained in the slim drug carrying tubes, the top ring is arranged at one end of the frame body, the actuating plates are arranged on the top ring through lantern rings in a penetrating mode, the frame body is composed of stretchable units, each stretchable unit is composed of two clamping arms and a plurality of pairs of clamping rings, the two clamping arms of each stretchable unit are hinged together, and the lower ends of the actuating plates are placed on the clamping rings of the stretchable unit at the uppermost end. The self-stretching intra-esophageal stent capable of carrying the local chemotherapy drugs is capable of expanding a narrow section of the esophagus effectively in a feeding process, being closed in a non-feeding state, preventing backflow of stomach content effectively, and reducing foreign body sensation of a patient in the non-feeding state remarkably. Meanwhile, the chemotherapy drugs are carried by the intra-esophageal stent, local chemotherapy is achieved while the esophagus is expanded, and a better drug delivery route is provided for tumor chemotherapy.

Description

technical field [0001] The invention relates to the field of medical devices, in particular to a self-stretching esophageal stent capable of carrying local chemotherapy drugs. Background technique [0002] At present, cancer is one of the three major killers of human diseases, and the mortality rate of patients is relatively high. However, after decades of careful research by people in the medical and health circles, therapeutic drugs continue to appear, and medical methods are also continuously improved, such as the treatment of cancer caused by malignant tumors. For esophageal stenosis, clinicians put in stents to achieve the purpose of expanding the pipeline. Taking esophageal cancer as an example, esophageal cancer is one of the common malignant tumors of the digestive tract in my country, ranking sixth among malignant tumors in the world. Once discovered, it is mostly in the middle and late stage , The most common problem in patients with middle and advanced esophageal ca...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61F2/852A61M31/00
Inventor 朱小娟时振国
Owner HENAN UNIV OF SCI & TECH
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