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Traditional Chinese medicine composition containing suberect spatholobus stem and preparation method of composition

A technology of Glycyrrhiza chinensis and a composition, applied in the field of traditional Chinese medicine, can solve the problems of stimulating gastric mucosa, long course of treatment, inhibiting cardiac function, etc., and achieves the effects of controllable quality and good curative effect.

Inactive Publication Date: 2014-01-15
TIANJIN TIANSHI BIOLOGICAL DEV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Since coronary heart disease is a chronic disease, the course of drug treatment is long, and long-term use of drugs can cause serious adverse reactions such as headache, cough, stimulation of gastric mucosa, hypotension, inhibition of heart function, and damage to liver and kidney functions.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0083] The active ingredients are extracted from the raw materials according to the following parts by weight: 1 part of seabuckthorn, 3 parts of safflower, 1 part of Caulis Spatholobus, 2 parts of Chuanxiong, and 1 part of Corydalis Corydalis.

[0084] (1) Preparation of extracts of seabuckthorn, safflower and spaghetti

[0085] Take seabuckthorn, safflower, and spatholobus medicinal materials, grind them, add ethyl acetate and 70% ethanol at a volume ratio of 1:2, heat and extract twice, the first time is 1 hour, the second time is 1 hour, and the filtrates are combined to obtain Extract I, add 70% ethanol to the medicinal dregs, heat and reflux for extraction twice, the first time for 0.5 hours, the second time for 0.5 hours, the filtrates are combined to obtain the extract II, the combined extracts I and II are concentrated into an extract, and 50 % ethanol to dissolve the extract, adopt macroporous resin AB-8 to separate it, and first elute with water to obtain eluent I;...

Embodiment 2

[0090] Active components are extracted from the raw materials according to the following parts by weight: 25 parts of seabuckthorn, 30 parts of safflower, 3 parts of Caulis Spatholobus, 15 parts of Chuanxiong, and 3 parts of Corydalis Corydalis.

[0091] (1) Preparation of extracts of seabuckthorn, safflower and spaghetti

[0092] Take seabuckthorn, safflower, and spaghetti, pulverize them, add ethyl acetate and 70% ethanol at a volume ratio of 1:2, heat and extract twice, the first time is 3 hours, the second time is 2 hours, and the filtrates are combined to obtain Extract I, add 70% ethanol to the medicinal dregs, heat and reflux for extraction twice, the first time is 1.5 hours, the second time is 1 hour, the filtrates are combined to obtain the extract II, the combined extracts I and II are concentrated into an extract, and 50 % ethanol to dissolve the extract, adopt macroporous resin X-5 to separate it, and first elute with water to obtain eluent I; then elute with 60% e...

Embodiment 3

[0097] Active components are extracted from the raw materials according to the following parts by weight: 2 parts of seabuckthorn, 5 parts of safflower, 1 part of Caulis Spatholobus, 3 parts of Chuanxiong, and 1 part of Corydalis Corydalis.

[0098] (1) Preparation of extracts of seabuckthorn, safflower and spaghetti

[0099] Take seabuckthorn, safflower and spaghetti, pulverize them, add ethyl acetate and 70% ethanol with a volume ratio of 1:2, heat and extract twice, the first time is 1.5 hours, the second time is 1.5 hours, and the filtrates are combined to obtain Extract I, add 70% ethanol to the dregs, heat and reflux for extraction twice, the first time for 1 hour, and the second time for 1 hour, the filtrates are combined to obtain Extract II, the combined Extracts I and II are concentrated into an extract, and 50 % ethanol to dissolve the extract, adopt macroporous resin AB-8 to separate it, and first elute with water to obtain eluent I; then elute with 55% ethanol, th...

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PUM

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Abstract

The invention discloses a traditional Chinese medicine composition containing suberect spatholobus stem. The composition comprises the following components in parts by weight: 1-25 parts of sea-buckthorn, 3-30 parts of safflower, 1-3 parts of suberect spatholobus stem, 2-15 parts of Sichuan lovage rhizome and 1-3 parts of rhizoma corydalis. The invention also discloses a preparation method of the traditional Chinese medicine composition. The preparation method comprises the steps of extracting active ingredients and preparing the finished product according to the formula. The traditional Chinese medicine composition makes the best of the treatment effects of active pharmaceutical ingredients on cardiovascular diseases, adopts scientific matching, generates synergistic effects, has better curative effects and more controllable quality than traditional sea-buckthorn extract preparations and is suitable for industrial production.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating cardiovascular diseases and a preparation method thereof, belonging to the field of traditional Chinese medicines. Background technique [0002] With the continuous improvement of people's living standards, changes in diet structure, population aging is becoming more and more obvious, and the incidence of coronary heart disease is increasing day by day. Coronary heart disease is a heart disease caused by narrowing of the lumen caused by coronary atherosclerosis, which causes myocardial blood supply and oxygen supply disturbance, and is known as the "world killer". As far as the whole world is concerned, coronary heart disease has become one of the most serious diseases threatening human health in the past half century, and it is the main cause of death in the United States and some industrialized countries. According to the statistics of the World Health Organization, 24....

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/66A61P9/00A61P9/10
Inventor 崔卜东贾林
Owner TIANJIN TIANSHI BIOLOGICAL DEV
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