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Analytical method of vaginal secretion

A technology of vaginal secretions and analysis methods, applied in the direction of biological testing, material inspection products, etc., can solve the problems of inability to reflect cleanliness, lack of detection system, high specificity, etc., to avoid subjectivity and incompleteness, increase Mutual recognition and reliability effects

Active Publication Date: 2014-05-14
北京中生金域诊断技术股份有限公司
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  • Application Information

AI Technical Summary

Problems solved by technology

Routine detection of vaginal secretions clinically is divided into two categories: the first type is morphological wet film microscopy using a microscope. The advantage is that the formed components of vaginal secretions can be directly observed. Low, can not correctly reflect the biochemical situation of functional normal bacteria and pathogenic bacteria, and manual operation has a certain degree of subjectivity and randomness; the other is to use biochemical methods to perform dry chemical detection of vaginal secretions , can reflect the functional status of normal vaginal bacteria and pathogenic bacteria at this time from the functional point of view. This method has high specificity, but it cannot reflect the cleanliness situation at this time, and due to the subjectivity of manual interpretation and the heavy workload of doctors , affecting the detection speed
At present, clinically, vaginal secretions are mostly detected by a single method, and no detection system has been formed, which cannot reflect the morphological (physical) and functional (chemical) conditions at the same time, which is not conducive to clinical treatment

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0070] The results of vaginal microbial ecological status are as follows:

[0071] 1. Vaginal secretions are yellow or purulent, this is the main factor item, and the weight coefficient is 0.014*4;

[0072] 2. With basal cells, this item is required, and the weight coefficient is 0.045*3;

[0073] 3. The number of white blood cells or pus cells is greater than 15 / HPF, this item is required, and the weight coefficient is 0.045*5;

[0074] 4. The reduction of lactobacilli and the proliferation of miscellaneous bacteria are necessary items, and the weight coefficient is 0.045*5*2;

[0075] 5. The biochemical indicators are: H2O2 abnormality, LE abnormality, GADP or GUS abnormality, this item is required, and the weight coefficient is 0.045*4*3.

[0076] According to the results of the ecological status of vaginal microorganisms above, the calculated value is 1.406, and the weight value of vaginitis greater than aerobic bacteria is vi>0.32. The result analyzed that what the pat...

Embodiment 2

[0078] The results of vaginal microbial ecological status are as follows:

[0079] 1. Vaginal secretions are in the form of foam, which is the main factor item, and the weight coefficient is 0.014*4;

[0080] 2. The trichomoniasis item shows "yes", this item is required, and the weight coefficient is 0.045*3.

[0081] According to the results of the ecological status of vaginal microorganisms above, the calculated value is 0.191, which is greater than the weight value of trichomonas vaginitis vi>0.09. When performing background calculations, all matching results will be screened out, but because this item has "drip Insects” option, this item is the only important factor to identify the results must be selected, therefore, the analysis results calculated in the above calculation process are deduced as trichomonas infection, and finally clinicians can analyze the patient’s trichomonas vaginitis according to the results.

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Abstract

The invention discloses an analytical method of vaginal secretion, which comprises the following steps: S1, extracting a vaginal secretion property characteristic sample of a patient, extracting a vaginal secretion morphological characteristic sample of the patient, extracting a preformed enzyme characteristic sample of dominant bacteria and pathogenic bacteria in vaginal secretion of the patient, extracting a metabolite characteristic sample of dominant bacteria and pathogenic bacteria in vaginal secretion of the patient, extracting a drug susceptibility characteristic sample of pathogenic microorganism in vaginal secretion of the patient, and extracting a bacterial structure component characteristic sample of the patient; S2, establishing an analytic model; S3, comparing all the characteristic samples in S1 with the model in S2 to obtain specific infective pathogens infected by the patient. The method combines analytic methods of morphology and biochemical function, and improves the mutual recognition and reliability of the determination results. The method is more comprehensive and improved than traditional examination methods, can help clinical doctors further analyze definite pathogens of vaginal infection, and increases clinic diagnosis and treatment efficiency.

Description

technical field [0001] The invention relates to the technical field of medical clinical testing, in particular to an analysis method of vaginal secretions. Background technique [0002] At present, the clinical prevention and treatment of vaginal infection is facing the problems of low cure rate and high recurrence rate. The main reason for this phenomenon is that clinicians are often eager to treat without first identifying the pathogenic microorganisms, that is, without a clear diagnosis, which leads to treatment failure. most common cause. [0003] Routine detection of vaginal discharge (abbreviated as routine leucorrhea) is an important medical examination item most widely used in clinical practice, and it mainly detects female reproductive tract infections. Routine detection of vaginal secretions clinically is divided into two categories: the first type is morphological wet film microscopy using a microscope. The advantage is that the formed components of vaginal secre...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/48
Inventor 王加义王淳玉赵玉林李洪青
Owner 北京中生金域诊断技术股份有限公司
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