Method for monitoring faults in fermentation process based on MICA-OCSVM

A fermentation process and fault monitoring technology, applied in electrical program control, comprehensive factory control, comprehensive factory control, etc., can solve application limitations, cannot clearly select the number of main independent components, and cannot effectively distinguish non-Gaussian information from Gaussian information. information, etc.

Active Publication Date: 2014-06-04
BEIJING UNIV OF TECH
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Problems solved by technology

However, the actual industrial process is mostly a mixed distribution of Gaussian and non-Gaussian, so the above method is limited by the assumption that the process variable obeys a specific distribution
Some scholars use PCA and ICA step-by-step modeling to solve this problem,

Method used

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  • Method for monitoring faults in fermentation process based on MICA-OCSVM
  • Method for monitoring faults in fermentation process based on MICA-OCSVM
  • Method for monitoring faults in fermentation process based on MICA-OCSVM

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Experimental program
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Embodiment Construction

[0047] Penicillin is an important antibiotic with high efficiency, low toxicity and wide clinical application. Its production process is a typical dynamic, nonlinear, multi-stage batch production process. PenSim2.0, a penicillin simulation platform developed by the process monitoring and technology group of Illinois State Institute of Technology in the United States, provides a standard platform for the monitoring, fault diagnosis and control of penicillin intermittent production process. A series of simulations of the penicillin fermentation process can be realized on this platform. Relevant studies have shown the practicability and effectiveness of this simulation platform, and it has become an internationally influential penicillin simulation platform.

[0048] This experiment takes PenSim2.0 as the simulation research object, sets the sampling interval as 1h, and selects 10 process variables to monitor the process operation status, as shown in Table 1. 31 batches of normal...

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Abstract

The invention discloses a novel method for achieving real-time fault monitoring on a penicillin fermentation process. In order to guarantee safety and stability of the penicillin fermentation process, it is necessary to establish an effective process monitoring scheme to detect abnormal phenomena timely. The method comprises two steps of off-line modeling and on-line monitoring. The step of off-line modeling comprises the steps of firstly carrying out processing on three-dimensional data of the fermentation process, then extracting independent element information of the data by adopting ICA, and finally carrying out modeling by utilizing OCSVM to structure monitoring statistical magnitude and determining a control limit by utilizing a kernel density estimation method. The step of on-line monitoring comprises the steps of carrying out processing on newly collected data according to a model, calculating the statistical magnitude of the data, and comparing the statistical magnitude and the control limit to judge whether the fermentation process runs normal or not. According to the method for monitoring the faults in the fermentation process based on the MICA-OCSVM, the assumption that a fermentation process variable subjects to Gaussian distribution or non-Gaussian distribution or other distributions is not needed, and the accuracy rate of fault monitor is high.

Description

technical field [0001] The invention relates to the field of data-driven fault diagnosis technology, in particular to a fault diagnosis technology for batch processes. The data-driven method of the present invention is a specific application in fault monitoring of a typical batch process—penicillin fermentation process. Background technique [0002] In recent decades, batch processes have attracted much attention because they can meet the demands of producing high value-added products. However, its mechanism is complicated, its operation complexity is high, and its product quality is easily affected by uncertain factors. As a typical batch process, the penicillin fermentation process has the characteristics of strong nonlinearity, dynamics, and mixed Gaussian distribution. In order to ensure the safety and stability of the fermentation process operating system, an effective process monitoring scheme is established to detect timely Anomalies are necessary. [0003] At pres...

Claims

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Application Information

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IPC IPC(8): G05B19/418
CPCY02P90/02
Inventor 王普张亚潮高学金崔宁
Owner BEIJING UNIV OF TECH
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