Measurement method and measurement equipment special for exhaustive swimming experiments of rats and mice

Abstract

The invention provides a measurement method and measurement equipment special for exhaustive swimming experiments of rats and mice. The equipment comprises a barrel, a constant temperature control system and a load bearing device. The barrel is filled with water, the constant temperature control system controls the temperature of the water in the barrel, and the load bearing device provided with a cavity and a cover is tied to a rat or a mouse. When the cover is closed, the cavity is sealed, and the dead weight of the load bearing device is larger than or equal to the buoyancy of the load bearing device completely immersed in the water. The measurement method using the measurement equipment special for the exhaustive swimming experiments of the rats and the mice has the advantages of measurement accuracy and simple structure.

Description

technical field [0001] The invention relates to a measuring method and equipment specially used for exhaustive swimming experiments of rats and mice. Background technique [0002] The exhaustive swimming test is a classic behavioral experiment that reflects the body's athletic ability, and is widely used in basic research in sports science, military medicine, rehabilitation medicine, geriatric medicine, neuroscience and pharmacology. In this experiment, 6% of the weight-bearing rats are placed in water with a water temperature of 30°C-33°C, and the time to swim to exhaustion is observed to reflect the exercise capacity and fatigue of the rats. At present, it is generally accepted that the cumulative time of rats and mice submerged in water reaches 10 seconds as the standard of exhaustion. Because the rats are struggling fiercely in the water, most of the rats will sink into the water several times for a short period of time. It is impossible to accurately judge whether the ...

AI Technical Summary

Problems solved by technology

Because the rats are struggling fiercely in the water, most rats will sink into the water several times for a short time, and it is impossible to accurately judge whether the rats are above or below the water by visual observation, so that the timing cannot be accumulated accurately, resulting in large timing errors

In addition, because the weight itself has buoyancy in the water, the existing equipment cannot accurately adjust the corresponding load according to the weight of the rats and mice, that is, it cannot guarantee that the load is always 6% of the body weight

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