Traditional Chinese medicine compound composition with anti-liver cancer activity and its preparation method and application

A technology for anti-liver cancer and composition, which is applied in the field of traditional Chinese medicine compound composition and its preparation, can solve the problems of inconspicuous curative effect, large dosage, and many impurities, and achieve reliable and reliable curative effect, low toxic and side effects, and scientific and reasonable proportioning Effect

Active Publication Date: 2018-05-01
NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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Problems solved by technology

However, the current reported anti-hepatic cancer drugs have a large dosage, many impurities, and the curative effect is not obvious.

Method used

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  • Traditional Chinese medicine compound composition with anti-liver cancer activity and its preparation method and application
  • Traditional Chinese medicine compound composition with anti-liver cancer activity and its preparation method and application
  • Traditional Chinese medicine compound composition with anti-liver cancer activity and its preparation method and application

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preparation example Construction

[0037] 2. the preparation method of the Chinese medicine compound composition with anti-liver cancer activity of the present invention, it may further comprise the steps:

[0038] (1) Get 10 grams of Zedoary Curcuma and 10 grams of Rhizoma Cyperi in parts by weight, add 15 times the amount of water of medicinal materials, extract by steam distillation for 2 hours, and collect volatile oil;

[0039] (2) Take 6 grams of Bupleurum bupleurum in vinegar, 20 grams of Hedyotis diffusa, 10 grams of August Zha, and 15 grams of Shanzi mushroom in parts by weight. , adding ethanol in a volume 10 times the weight of the total medicinal material, reflux extraction twice, each time for 3 hours, combining the extracts, concentrating under reduced pressure at 50-70 degrees Celsius, and getting the concentrate on a macroporous adsorption resin column, first eluting with water, Then sequentially elute with ethanol with a volume concentration of 20% to 70%; collect the ethanol eluate with a comb...

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Abstract

The invention discloses a Chinese medicine compound composition with anti-liver cancer activity, its preparation method and its application. The Chinese medicine compound composition consists of 6-18 parts of Bupleurum bupleurum vinegar, 10-30 parts of Rhizoma Cyperi and 20 parts of Hedyotis diffusa ~60 parts, 10~30 parts of August Zha, 15~45 parts of Shanzi mushroom, 10~30 parts of Curcuma. Experiments have shown that the traditional Chinese medicine compound composition with anti-liver cancer activity provided by the invention has strict medication, scientific and reasonable proportioning, anti-cancer and detoxification, soothing the liver and relieving depression, pain relief and other effects, and has a strong killing effect on liver cancer. It has a wide range; it can improve the immunity of tumor patients, prolong the quality of life, and has high safety and low toxic and side effects. At the same time, the preparation method provided by the invention has stable quality, high content of extracted active ingredients, strong operability, and is suitable for large-scale industrial production.

Description

technical field [0001] The invention relates to a traditional Chinese medicine, in particular to a compound traditional Chinese medicine composition with anti-liver cancer activity and its preparation method and application. Background technique [0002] Liver cancer refers to malignant tumors that occur in the liver, including primary liver cancer and metastatic liver cancer. Primary liver cancer is one of the most common malignant tumors in clinical practice. There are about 600,000 liver cancer patients, ranking fifth among malignant tumors. According to cell type, primary liver cancer can be divided into hepatocellular carcinoma, cholangiocellular carcinoma and mixed liver carcinoma. According to the shape of the tumor, it can be divided into nodular type, massive type and diffuse type. [0003] Liver cancer is the third most common malignant tumor in mortality after gastric cancer and esophageal cancer. The initial symptoms are not obvious, and the late stage mainly m...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61P35/00
Inventor 程海波周仲瑛沈卫星李柳孙东东徐长亮谭佳妮沈政洁吴东东
Owner NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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