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A traditional Chinese medicine composition for treating ischemic stroke and post-stroke depression and its preparation method

A technology of ischemic stroke and composition, which is applied in the direction of drug combination, medical preparations containing active ingredients, pharmaceutical formulas, etc., which can solve the problems of limited clinical application, lack of effective therapy, and poor long-term curative effect. Achieve the effects of reducing cerebral ischemic area, improving body weight and activity, and facilitating preparation and large-scale production

Active Publication Date: 2017-05-17
XIYUAN HOSPITAL OF CHINA ACAD OF CHINESE MEDICAL SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Western medicine lacks effective therapy in the treatment of stroke recovery. Most of the medicines have limitations, the long-term curative effect is not good, and there are many problems in the treatment, so the wide clinical application is greatly limited.
The clinical curative effect of traditional Chinese medicine in the treatment of ischemic stroke related diseases is definite, the toxic and side effects are relatively small, and it is widely used in clinical practice. The advantages in clinical treatment far outweigh the disadvantages

Method used

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  • A traditional Chinese medicine composition for treating ischemic stroke and post-stroke depression and its preparation method
  • A traditional Chinese medicine composition for treating ischemic stroke and post-stroke depression and its preparation method
  • A traditional Chinese medicine composition for treating ischemic stroke and post-stroke depression and its preparation method

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] Embodiment 1 Chinese medicine composition

[0041] prescription:

[0042] Ginseng 60g, Ginkgo biloba 120g, Scutellaria baicalensis 60g, Gardenia 60g, Gastrodia elata 60g, Chuanxiong 60g, Hypericum perforatum 60g.

[0043] Preparation method:

[0044] All raw materials are crushed and then decocted and extracted 4 times. The amount of water added each time is 20 times the total weight of the raw materials. The decoction time is 3 hours each time. The decoction is combined, concentrated to a relative density of 1.05, and 95% ethanol is added. sink, stand overnight, take the supernatant, recover ethanol under reduced pressure until there is no alcohol smell, and concentrate to a thick paste to obtain the traditional Chinese medicine composition.

Embodiment 2

[0045] Embodiment 2 Chinese medicine composition

[0046] prescription:

[0047] Ginseng 6g, Ginkgo biloba 12g, Scutellaria baicalensis 6g, Gardenia 6g, Gastrodia elata 6g, Chuanxiong 6g, Hypericum perforatum 6g, Salvia miltiorrhiza 6g, Rhodiola rosea 6g.

[0048] Preparation method:

[0049] After crushing all raw materials, add water and decoct them for extraction 3 times. The amount of water added each time is 15 times the total weight of the raw materials. The decoction time is 2 hours each time. The water decoctions are combined, concentrated to a relative density of 1.10, and 95% ethanol alcohol is added. sink, stand overnight, take the supernatant, recover ethanol under reduced pressure until there is no alcohol smell, and concentrate to a thick paste to obtain the traditional Chinese medicine composition.

Embodiment 3

[0050] Embodiment 3 Chinese medicine composition

[0051] prescription:

[0052] Ginseng 1000g, Ginkgo biloba 2000g, Scutellaria baicalensis 1000g, Gardenia 1000g, Gastrodia elata 1000g, Chuanxiong 1000g, Hypericum perforatum 1000g, Salvia miltiorrhiza 1000g.

[0053] Preparation method:

[0054] After crushing all raw materials, add water to decoct and extract twice, each time the amount of water added is 10 times of the total weight of the raw materials, and the decoction time is 1.5 hours each time, the decoction is combined, concentrated to a relative density of 1.15, and 95% ethanol is added Alcohol precipitation, standing overnight, taking the supernatant, recovering ethanol under reduced pressure until it has no alcohol smell, and concentrating to a thick paste to obtain the traditional Chinese medicine composition.

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PUM

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Abstract

The invention relates to a traditional Chinese medicine composition for treating ischemia apoplexy and post-stroke depression and a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the following main raw materials in parts by weight: 10-100 parts of ginseng, 10-500 parts of ginkgo leaves, 10-150 parts of radix scutellariae, 10-200 parts of fructus gardenia, 10-200 parts of rhizoma gastrodiae, 10-200 parts of ligusticum wallichii and 10-200 parts of hyperforin perforatum. The traditional Chinese medicine composition is obvious in treatment effects on ischemia apoplexy and post-stroke depression. The pharmacodynamic test proves that the traditional Chinese medicine composition is excellent in treatment effects on ischemia apoplexy and post-stroke depression.

Description

technical field [0001] The invention belongs to the field of Chinese herbal medicines, in particular to a traditional Chinese medicine composition for treating ischemic stroke and post-stroke depression and a preparation method thereof. Background technique [0002] At present, the incidence of stroke in my country is relatively high, and ischemic stroke accounts for 60-80% of strokes. Its high disability rate, high mortality rate and its sequelae—post-stroke depression all bring double pressure on medical care and social economy. Western medicine lacks effective therapy in the treatment of stroke recovery period. Most of the medicines have limitations, the long-term efficacy is not good, and there are many problems in the treatment, so the wide application in clinical practice is greatly limited. The clinical curative effect of traditional Chinese medicine in the treatment of ischemic stroke related diseases is definite, the toxic and side effects are relatively small, and ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8988A61P9/10A61P25/24
Inventor 刘建勋徐立任钧国林成仁宋文婷姚明江
Owner XIYUAN HOSPITAL OF CHINA ACAD OF CHINESE MEDICAL SCI
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