Method for identifying whether ephedrine and/or pseudo ephedrine are/is added to weight-reducing type traditional Chinese medicine or health care products

Abstract

A method for identifying whether ephedrine and/or pseudo ephedrine are/is added to weight-reducing type traditional Chinese medicine or health care products rapidly identifies whether illicit ephedrine and/or pseudo ephedrine are/is added to weight-reducing type traditional Chinese medicine preparations or health care food through a two-dimensional correlation infrared spectroscopy method and includes the following steps of preparing potassium bromide tablets, collecting a dynamic spectrum, obtaining characteristic peaks, conducting comparison and judgment to determine whether a to-be-tested sample contains ephedrine and/or pseudo ephedrine, wherein two-dimensional correlation spectra of the obtained to-be-tested sample, an ephedrine standard sample and a pseudo ephedrine standard sample are compared and judged, and characteristic peaks, correlation peaks and cross peaks are sequentially contrasted for a two-dimensional correlation power spectrum, a two-dimensional correlation synchronous spectrum and a two-dimensional correlation asynchronous spectrum.

Description

technical field [0001] The invention relates to a method for quickly identifying whether ephedrine and / or pseudoephedrine are added to weight-loss traditional Chinese medicines, and belongs to the technical field of medical analysis. Background technique [0002] In recent years, in order to speed up the curative effect of traditional Chinese medicine and seek high profits, some traditional Chinese medicine and health product manufacturers have added ephedrine, pseudoephedrine or a mixture of the two in weight loss traditional Chinese medicine and health care products (in the present invention, ephedrine actually refers to ephedrine hydrochloride Salt, i.e. the customary saying of ephedrine hydrochloride, pseudoephedrine is also like this, still refer to ephedrine hydrochloride, pseudoephedrine hydrochloride) according to the customary saying behind), although ephedrine and pseudoephedrine can increase the body's calorie consumption, promote fat decomposition, and in the shor...

AI Technical Summary

Problems solved by technology

When the amount of ephedrine and / or pseudoephedrine added to weight-loss traditional Chinese medicine is greater than 10%, most of the characteristic peaks of ephedrine and / or pseudoephedrine can be detected on the infrared spectrum, that is, it can be judged whether the weight-loss traditional Chinese medicine is Added ephedrine and / or pseudoephedrine, but when the added concentration is lower (<5%), most of the characteristic peaks of ephedrine and / or pseudoephedrine are covered by the peaks of the traditional Chinese medicine matrix, or even completely embedded, even if there are one or two The weak peak is close to the characteristic peak of ephedrine or pseudoephedrine, and it is difficult to qualitatively distinguish whether ephedrine and / or pseudoephedrine are added to weight loss traditional Chinese medicines

like figure 1 as shown, figure 1 E at the bottom of A P It is the infrared spectrum of the standard ephedrine, and the three spectral lines above it are the infrared spectra of weight-loss traditional Chinese medicines with 0%, 5%, and 10% ephedrine added; figure 1 The PS located at the bottom in B is the infrared spectrum of the standard pseudoephedrine, and the three spectral lines above it are the infrared spectra of weight-loss traditional Chinese medicines added with 0%, 5%, and 10% ephedrine respectively. It can be seen from the figure that when a small amount of ephedrine is added ephedrine and / or pseudoephedrine (e.g. figure 1 The amount of not more than 5% in Chinese medicine), the peaks of other substances in traditional Chinese medicine wrap the characteristic peaks of ephedrine or pseudoephedrine, so that simple one-dimensional infrared spectroscopy cannot accurately identify the existence of ephedrine and / or pseudoephedrine

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