Extracranial Standing Wave Suppression Method Based on Transcranial Focusing of High Intensity Ultrasound

A high-intensity, standing wave technology, used in ultrasonic therapy, treatment and other directions, can solve the problems of no research on the selection of conversion time interval, no research and discussion on the method of reducing standing waves, etc. Wave-cutting ability, pain-relieving effect

Active Publication Date: 2018-01-19
TIANJIN MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the former only studies the standing wave reduction method in the tissue, and does not discuss the standing wave reduction method between the transducer and the skull
On the other hand, the selection of switching intervals for the random switching phase method has not been studied

Method used

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  • Extracranial Standing Wave Suppression Method Based on Transcranial Focusing of High Intensity Ultrasound
  • Extracranial Standing Wave Suppression Method Based on Transcranial Focusing of High Intensity Ultrasound
  • Extracranial Standing Wave Suppression Method Based on Transcranial Focusing of High Intensity Ultrasound

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0047] figure 1 It is a schematic diagram of the transcranial focusing space of the spherical coronal concave spherical phased transducer, figure 2 The example model is shown here, where the squamous part of the temporal bone is used as the bone acoustic window, and the transducer is irradiated with a spherical coronal concave spherical 64-element phased array transducer at a frequency of 0.6MHz as an example, as follows steps to implement.

[0048] S1: Use the random function in Matlab to generate a sequence of random 0 or π. In this example, the acoustic window model selects the temporal bone window, and the intracranial focus is located at the geometric focus of the transducer, that is, the focal point is set at a distance of 80mm from the transducer.

[0049] S2: According to the position of the intracranial target area and the zoom range of the phased transducer, the selected treatment target depth is =25mm, that is, the distance between the skull and the phased tran...

Embodiment 2

[0058] S1: Use the random function in Matlab to generate a random sequence of 0, π / 2 or π. In this example, the acoustic window model selects the temporal bone window, and the intracranial focus is located at the geometric focus of the transducer, that is, the focal point is set at a distance of 80mm from the transducer.

[0059] S2: According to the position of the intracranial target area and the zoom range of the phased transducer, the selected treatment target depth is =25mm, that is, the distance between the skull and the phased transducer is =55mm. Using formula (1) As an excitation signal, the generated random sequence is added to the element excitation function at regular time intervals, and formula (1) is rewritten as formula (2) . in The phase of 0, π / 2 or π is taken from the 0, π / 2 or π random phase sequence generated by the random function, formula (3) (n=1,2,3...) read once value, is the phase transition time interval.

[0060] S3: Select differen...

Embodiment 3

[0063] S1: Use the random function in Matlab to generate random sequences of 0, π / 2, π or 3π / 2. In this example, the acoustic window model selects the temporal bone window, and the intracranial focus is located at the geometric focus of the transducer, that is, the focal point is set at a distance of 80mm from the transducer.

[0064] S2: According to the position of the intracranial target area and the zoom range of the phased transducer, the selected treatment target depth is =25mm, that is, the distance between the skull and the phased transducer is =55mm. Using formula (1) As an excitation signal, the generated random sequence is added to the element excitation function at regular time intervals, and formula (1) is rewritten as formula (2) . in The phase of 0, π / 2, π or 3π / 2 is taken from the random phase sequence of 0, π / 2, π or 3π / 2 generated by the random function, formula (3) (n=1,2,3...) read once value, is the phase transition time interval.

[0065]...

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Abstract

The invention discloses a method for suppressing standing waves generated during transcranial focusing of high-intensity ultrasound, which suppresses the standing waves formed due to the presence of skull bones during high-intensity focused ultrasound transcranial therapy, thereby reducing the intensity of standing waves and simultaneously improving A method of focusing energy in the focal zone. It includes the following steps: S1: use the random function in Matlab to generate a random phase sequence; S2: add the generated random phase sequence to the array element excitation function at a fixed time interval; S3: select different phase conversion time intervals, use the resident The wave ratio Ra evaluates the standing wave intensity, and selects the time interval with the best standing wave suppression effect; S4: Under the condition of other inputs unchanged, perform standing wave suppression according to the selected optimal phase conversion time interval, and use the adjusted excitation function to excite The transducer is focused. The invention can realize transcranial focusing while effectively suppressing standing waves, and has the effect of increasing energy in the focal region and accelerating temperature rise.

Description

technical field [0001] The invention relates to a method for suppressing the standing wave phenomenon generated by transcranial focusing of high-intensity ultrasound. The excitation function of each excitation array element is randomly changed by 0 or π at the same time, and the transcranial signal is modulated so that the outside of the skull The strength of the standing wave between the surface and the transducer is reduced while increasing the focal region energy. Background technique [0002] High-intensity focused ultrasound (HIFU) is a new type of non-invasive treatment technology, which emits ultrasonic waves from the outside and concentrates them on the treatment target area in the human body, so that the temperature of the target area rises instantly to above 60 degrees to kill the lesion in the target area tissue therapy techniques. This technology has been used in the treatment of prostate cancer, liver cancer, uterine fibroids, pancreatic cancer, breast cancer a...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61N7/02
Inventor 菅喜岐曾苗苗
Owner TIANJIN MEDICAL UNIV
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