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Extracranial standing wave suppression method for high-intensity ultrasound transcranial focusing

A high-intensity, standing wave technology, used in ultrasonic therapy, treatment and other directions, can solve the problems of no research on the selection of conversion time interval, no research and discussion on the method of reducing standing waves, etc. Wave attenuation ability, effect of reducing the intensity of standing waves

Active Publication Date: 2016-01-13
TIANJIN MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the former only studies the standing wave reduction method in the tissue, and does not discuss the standing wave reduction method between the transducer and the skull
On the other hand, the selection of switching intervals for the random switching phase method has not been studied

Method used

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  • Extracranial standing wave suppression method for high-intensity ultrasound transcranial focusing
  • Extracranial standing wave suppression method for high-intensity ultrasound transcranial focusing
  • Extracranial standing wave suppression method for high-intensity ultrasound transcranial focusing

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0047] figure 1 It is a schematic diagram of the transcranial focusing space of the spherical coronal concave spherical phased transducer, figure 2 The example model is shown here, where the squamous part of the temporal bone is used as the bone acoustic window, and the transducer is irradiated with a spherical coronal concave spherical 64-element phased array transducer at a frequency of 0.6MHz as an example, as follows Step implementation.

[0048] S1: Use the random function in Matlab to generate a sequence of random 0 or π. In this example, the acoustic window model selects the temporal bone window, and the intracranial focus is located at the geometric focus of the transducer, that is, the focal point is set at a distance of 80mm from the transducer.

[0049] S2: According to the position of the intracranial target area and the zoom range of the phased transducer, the selected treatment target depth is =25mm, that is, the distance between the skull and the phased tra...

Embodiment 2

[0058] S1: Use the random function in Matlab to generate a random sequence of 0, π / 2 or π. In this example, the acoustic window model selects the temporal bone window, and the intracranial focus is located at the geometric focus of the transducer, that is, the focal point is set at a distance of 80mm from the transducer.

[0059] S2: According to the position of the intracranial target area and the zoom range of the phased transducer, the selected treatment target depth is =25mm, that is, the distance between the skull and the phased transducer is =55mm. Using formula (1) As an excitation signal, the generated random sequence is added to the element excitation function at regular time intervals, and formula (1) is rewritten as formula (2) . in The phase of 0, π / 2 or π is taken from the 0, π / 2 or π random phase sequence generated by the random function, formula (3) (n=1,2,3...) read once value, is the phase transition time interval.

[0060] S3: Select differen...

Embodiment 3

[0063] S1: Use the random function in Matlab to generate random sequences of 0, π / 2, π or 3π / 2. In this example, the acoustic window model selects the temporal bone window, and the intracranial focus is located at the geometric focus of the transducer, that is, the focal point is set at a distance of 80mm from the transducer.

[0064] S2: According to the position of the intracranial target area and the zoom range of the phased transducer, the selected treatment target depth is =25mm, that is, the distance between the skull and the phased transducer is =55mm. Using formula (1) As an excitation signal, the generated random sequence is added to the element excitation function at regular time intervals, and formula (1) is rewritten as formula (2) . in The phase of 0, π / 2, π or 3π / 2 is taken from the random phase sequence of 0, π / 2, π or 3π / 2 generated by the random function, formula (3) (n=1,2,3...) read once value, is the phase transition time interval.

[0065]...

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Abstract

The present invention discloses an extracranial standing wave suppression method for high-intensity ultrasound transcranial focusing, which is used for suppressing standing waves formed due to the presence of a skull in high-intensity focused ultrasound transcranial treatment, so as to reduce intensity of the standing waves and enhance focused energy of a focal domain. The extracranial standing wave suppression method comprises the steps of: S1, generating a random phase sequence by utilizing a random function in a Matlab; S2, adding the generated random phase sequence into an array element excitation function at every fixed time interval; S3, selecting different phase shifting time intervals, utilizing a standing-wave ratio Ra to evaluate standing wave intensity, and selecting a time interval with the optimal standing wave suppression effect; S4, and conducting standing wave suppression according to the selected optimal phase shifting time interval under the condition of other unchanged input, and utilizing the adjusted excitation function to excite a transducer for focusing. The extracranial standing wave suppression method can achieve the effects of effectively suppressing the standing waves during transcranial focusing, and increasing accelerated temperature rise of the energy of the focal region.

Description

technical field [0001] The invention relates to a method for suppressing the standing wave phenomenon generated by transcranial focusing of high-intensity ultrasound. The excitation function of each excitation array element is randomly changed by 0 or π at the same time, and the transcranial signal is modulated so that the outside of the skull The strength of the standing wave between the surface and the transducer is reduced while increasing the focal region energy. Background technique [0002] High-intensity focused ultrasound (HIFU) is a new type of non-invasive treatment technology, which emits ultrasonic waves from outside the body and gathers them into the treatment target area in the human body, so that the temperature of the target area rises instantly to above 60 degrees to kill the diseased tissue in the target area. treatment techniques. This technology has been used in the treatment of prostate cancer, liver cancer, uterine fibroids, pancreatic cancer, breast c...

Claims

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Application Information

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IPC IPC(8): A61N7/02
Inventor 菅喜岐曾苗苗
Owner TIANJIN MEDICAL UNIV
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