Procyanidine effervescent tablet and preparation method thereof

A technology for procyanidin foam and procyanidin, which is applied to the field of procyanidin effervescent tablet and its production, can solve the problems of poor eating taste, inconvenience in carrying and the like, and achieve the effects of easy promotion, convenient operation and simple process

Inactive Publication Date: 2016-02-24
INST OF AGRO FOOD SCI & TECH CHINESE ACADEMY OF AGRI SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The effervescent tablet overcomes the shortcomings of traditional ora

Method used

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  • Procyanidine effervescent tablet and preparation method thereof
  • Procyanidine effervescent tablet and preparation method thereof

Examples

Experimental program
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preparation example Construction

[0042] The preparation methods in the following examples are conventional methods unless otherwise specified; the experimental materials used are purchased from conventional biochemical reagent manufacturers unless otherwise specified.

[0043] The technological process of extracting proanthocyanidins from Huaniu apple apple peel:

[0044] Step A, flash extraction:

[0045] Take 100g of Huaniu apple peel, put it in a beaker, add 300g of deionized water, and extract it with a flash extractor at a speed of about 3000 rpm for 5 minutes.

[0046] Step B, sieving:

[0047] The resulting extract is filtered through a 120-mesh sieve to facilitate subsequent centrifugation and suction filtration operations.

[0048] Step C, centrifugal suction filtration:

[0049] Centrifuge at a speed of 5000r / min for 10min, and then take out the supernatant for suction filtration.

[0050] Step D, rotary evaporation concentration:

[0051] The filtrate obtained by suction filtration was rotary ...

Embodiment 1

[0055] For Huaniu apple peel proanthocyanidin extract effervescent tablet, weigh the following materials:

[0056] Huaniu Apple Peel Proanthocyanidins Extract 4g

[0057] Disintegrant 44.8g

[0058] Povidone K30 (binder) 0.8g

[0059] Polyethylene glycol 6000 (binder) 2.4g

[0060] Silica 0.4g

[0061] Magnesium stearate 0.4g

[0062] Soluble starch 1.6g

[0063] Flavoring agent 1.6g

[0064] Other accessories 24g

[0065] Implementation method: Weigh each raw material according to the materials and weights listed above, with a total weight of 80g, fully mix the powders of each material, crush and sieve, and directly compress tablets on a powder rotary tablet machine with a filling depth of 10mm and a pressure of 30kN. The tablet thickness is 4mm and the tablet diameter is 12mm. About 160 tablets are obtained by coating with a coating machine, and each tablet weighs about 500 mg.

Embodiment 2

[0067] For Huaniu apple peel proanthocyanidin extract effervescent tablet, weigh the following materials:

[0068]Huaniu Apple Peel Proanthocyanidins Extract 4g

[0069] Disintegrant 44.8g

[0070] Polyethylene glycol 6000 3.2g

[0071] Silica 0.4g

[0072] Magnesium stearate 0.4g

[0073] Soluble starch 1.6g

[0074] Other accessories 25.6g

[0075] Implementation method is described with example 1.

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Abstract

The invention relates to a procyanidine effervescent tablet and a preparation method thereof. The preparation method comprises the following steps: using a Hua Niu apple procyanidine extract as a main raw material; adding a disintegrating agent, an excipient, a flavoring agent and food color, wherein the additives all meet the food sanitation and safety requirements; adopting a direct powder tabletting technology to form the procyanidine effervescent tablet with the certain shape. Procyanidine is a main polyphenol compound combined from different amounts of catechin or epicatechin, and research shows that the procyanidine has the pharmacological functions of protecting heart, improving study and memory functions of mice with study and memory impairments, resisting oxidation, preventing and treating cancer, adjusting blood fat, promoting hair growth and the like. According to the research, the extraction process of procyanidine in apple peel residue is optimized, procyanidine is developed into the procyanidine effervescent tablet, and not only can full utilization of resource be realized, but also a novel health food is additionally provided, so that the health condition of people and the life quality are improved.

Description

technical field [0001] The present invention relates to an effervescent tablet and a preparation method thereof, and more specifically, relates to a proanthocyanidin effervescent tablet which uses Huaniu apple peel proanthocyanidin extract as a main raw material and a preparation method thereof. Background technique [0002] Proanthocyanidins are a large class of polyphenolic compounds combined with different amounts of catechin or epicatechin. Studies have shown that proanthocyanidins can protect the heart, improve learning and memory functions in mice with learning and memory impairment, anti-oxidation, prevent and treat cancer, regulate Blood lipids, promoting hair growth and other pharmacological effects, and its high bioavailability, low toxicity, and superior biological activity make proanthocyanidins products popular all over the world, widely used in medicine, cosmetics, health care products and other fields, with huge market potential and economic benefits . [000...

Claims

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Application Information

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IPC IPC(8): A61K9/46A61K31/352A61K47/36A61K47/34A61P9/00A61P25/28A61P39/06A61P35/00A61P3/06A61P17/14
CPCA61K9/0007A61K9/2031A61K9/2059A61K31/352A61K2236/331A61K2236/51A61K2236/53
Inventor 来吉祥王凤忠黄璐璐方芳王东晖王艳幸岑璨李淑英李敏敏范蓓
Owner INST OF AGRO FOOD SCI & TECH CHINESE ACADEMY OF AGRI SCI
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