Method for detecting concentration of estrogen or estrogenic-like compound

A technology of estrogen and compounds, applied in the direction of biological testing, material inspection products, etc., can solve the problems of affecting detection, lack of information and results, etc.
CN105866441AActive Publication Date: 2016-08-17RES CENT FOR ECO ENVIRONMENTAL SCI THE CHINESE ACAD OF SCI
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
RES CENT FOR ECO ENVIRONMENTAL SCI THE CHINESE ACAD OF SCI
Publication Date
2016-08-17

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Abstract

The invention discloses a method for detecting concentration of an estrogen or estrogenic-like compound. The invention discloses a method for detecting the concentration of the compound having estrogenic effect in a sample. The method for detecting the concentration of the compound having estrogenic effect in the sample comprises a step of establishing an estrogen compound concentration-estrogen effect relation curve, wherein, the step comprises a process of preparing two-hybrid yeast saccharomycete liquid of two-hybrid yeast saccharomycete in a logarithmic phase. The method provides the reliable technical means for toxicity detection and risk assessment of environment mixing pollutants.
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Description

technical field

[0001] The invention relates to a method for detecting the concentration of estrogen or estrogen-like compounds, belonging to the field of biotechnology. Background technique

[0002] Estrogen receptor disruptors are one of the hotspots in the research of endocrine disruptors. Estrogen receptor disruptors in the water environment include natural estrogens and other substances / antiestrogens derived from various sources. They can cause adverse effects on organisms at lower exposure concentrations, and joint exposure in the environment often means the possibility of addition or even interaction. It is therefore very important to monitor the environmental levels of estrogen receptor disruptors and their adverse effects on organisms.

[0003] A number of agencies and organizations—including the U.S. Environmental Agency, the U.S. Department of Health and Human Services, the Organization for Economic Co-operation and Development, and others—have proposed lists of ...

Claims

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