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Qianqiandantong Granules for Cholelithiasis

A technology of qiandantong and granules, applied in medical preparations containing active ingredients, drug combinations, plant/algae/fungus/moss components, etc. Program, problems affecting bile secretion and excretion

Active Publication Date: 2019-12-20
GUIZHOU WARMEN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

So far, the effects achieved by the above-mentioned treatment methods are still not satisfactory for clinical patients: ①Although non-surgical treatment can partially or completely dissolve the stones formed by the patient in a short period of time, discharge or remove them
However, the treatment not only has a low success rate, but also costs too much (side effects, complications and high price), and cannot fundamentally solve the recurrence of stones.
In addition, there is no ideal solution for the treatment of bilirubin stones
② Although surgical treatment can completely remove the stone itself and its origin, the complications of surgery are still relatively high, especially surgical treatment of intrahepatic bile duct stones still has high complications and mortality
If the dredging function of the liver is abnormal, it will affect the secretion and excretion of bile; on the contrary, if the excretion of bile is not smooth, it will also affect the dredging of the liver

Method used

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  • Qianqiandantong Granules for Cholelithiasis

Examples

Experimental program
Comparison scheme
Effect test

preparation example 1

[0046] Preparation Example 1: Preparation of Qianjindantong Granules

[0047] Recipe (preparation of 1000g qiandantong granules): 750g Lismodium, 375g Polygonum cuspidatum, 375g Dandelion, 562.5g Capillary, 562.5g Desmodium, 187.5g Salvia, 187.5g Radix Cyperus, 187.5g Bupleurum, 187.5g Ume, Cassia seed 187.5g, stevioside 1g, dextrin appropriate amount to make the final particle weight 1000g.

[0048] Preparation method:

[0049] (1) Divide the ten herbs into medium pieces and set aside;

[0050] (2) Add 9 times the amount of water to decoct Lismodium and Desmodium for 2 hours, filter; add 7 times the amount of water to decoct and extract for 1.5 hours, filter; combine the two filtrates, and set aside;

[0051] (3) Add 9 times the amount of water to decoct and extract the remaining eight herbs for 2 hours, filter; add 7 times the amount of water to decoct and extract for 1.5 hours, filter; combine the filtrates twice, and set aside;

[0052] (4) Combine the filtrate obtaine...

preparation example 2

[0053] Preparation Example 2: Preparation of Qiandantong Granules

[0054] Recipe (preparation of Qiandantong Granules 1000g): 700g Lismodium, 400g Polygonum cuspidatum, 350g Dandelion, 500g Capillary, 600g Desmodium, 150g Salvia, 200g Zhixiangfu, 150g Bupleurum, 200g Ume, 150g Cassia, Stevia 0.5 g, an appropriate amount of dextrin to make the final particle weight 1000g.

[0055] Preparation method:

[0056] (1) Divide the ten herbs into medium pieces and set aside;

[0057] (2) Add 10 times the amount of water to decoct Lismodium chinensis and Desmodium desmodium together for 1 hour, filter; add 6 times the amount of water to decoct and extract for 2 hours, filter; combine the two filtrates, and set aside;

[0058] (3) Add 8 times the amount of water to decoct the rest of the herbs for 3 hours, filter; add 8 times the amount of water to decoct and extract for 1 hour, filter; combine the two filtrates, and set aside;

[0059] (4) Combine the filtrate obtained in step (2)...

preparation example 3

[0060] Preparation Example 3: Preparation of Qiandantong Granules

[0061] Recipe (preparation of qiandantong granule 1000g): 800g of syringa, 350g of knotweed, 400g of dandelion, 600g of capillary, 500g of desmodium, 200g of salvia, 150g of cyperus, 200g of bupleurum, 150g of black plum, 200g of cassia seed, 1g of stevia , An appropriate amount of dextrin makes the final particle weight 1000g.

[0062] Preparation method:

[0063] (1) Divide the ten herbs into medium pieces and set aside;

[0064] (2) Add 8 times the amount of water to decoct Lismodium chinensis and Desmodium chinensis together for 3 hours, and filter; add 8 times the amount of water to decoct the filter residue, extract for 1 hour, and filter; combine the two filtrates, and set aside;

[0065] (3) Add 10 times the amount of water to decoct the remaining eight herbs for 1 hour, filter; add 6 times the amount of water to decoct and extract for 2 hours, filter; combine the two filtrates, and set aside;

[...

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Abstract

The invention relates to herba lysimachiae eulektrol particles, in particular to herba lysimachiae eulektrol particles for treating cholelithiasis. The herba lysimachiae eulektrol particles are prepared from, by weight, 10-1,500 parts of glechoma longituba, 10-1,000 parts of rhizoma polygoni cuspidate, 10-1,000 parts of dandelions, 10-1,000 parts of oriental wormwood, 10-1,000 parts of herba lysimachiae, 10-500 parts of the root of red-rooted salvia, 10-500 parts of prepared rhizoma cyperi, 10-500 parts of radix bupleuri, 10-500 parts of dark plums, 10-500 parts of cassia seeds and a proper quantity of auxiliary materials. The invention further relates to a preparation method of the herba lysimachiae eulektrol particles. The herba lysimachiae eulektrol particles have excellent properties.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and relates to a medicine for treating cholelithiasis and a preparation method thereof, in particular to a composition of Qiandantong granules for treating cholelithiasis and a preparation method thereof. Background technique [0002] Cholelithiasis is a common clinical disease, frequently-occurring disease, and the incidence rate in my country is more than 10%, and it is increasing year by year. The formation mechanism of cholelithiasis is not yet fully understood, and it is generally believed to be related to the infectious inflammation of the hepatobiliary system, changes in bile composition, physicochemical properties, and fluid mechanics. In recent years, studies have shown that immune responses, immune complexes, and changes in the expression of certain genes may also be involved in the formation of cholelithiasis. With the deepening of research, it is believed that t...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8905A61K9/16A61P1/16
CPCA61K9/1652A61K36/233A61K36/282A61K36/288A61K36/39A61K36/482A61K36/53A61K36/537A61K36/704A61K36/736A61K36/8905A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2300/00
Inventor 梁斌杨槐张丽艳唐靖雯卢礼平彭政忠
Owner GUIZHOU WARMEN PHARMA
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