386results about How to "Good blood pressure effect" patented technology

The invention discloses burdock tea and a production method thereof. The burdock tea is prepared by processing 100 to 150 parts of burdock, 2 to 10 parts of medlar, 1 to 5 parts of date and 2 to 10 parts of Astragalus root through raw material treatment, cutting processing, baking, ingredient stewing and rebaking. The burdock tea has the characteristics that the production process is simple, the process is reasonable, raw materials are reasonably mixed, the nutrition is rich, original nutrients of the main materials and the auxiliary materials are adequately maintained, the taste is unique, and the healthcare effect is good.

The invention discloses a liposome solid preparation of a losartan potassium hydrochlorothiazide pharmaceutical composition and a preparation method thereof. In the invention, active components of losartan potassium and hydrochlorothiazide and specific combined hydrogenated yolk lecithin, cholesterol and poloxamer 188 are prepared into a liposome which is then mixed with other pharmaceutical accessories to prepare the solid preparation, thereby greatly improving the pharmaceutical stability and bioavailability and having stable and lasting effect, small side effect and obvious curative effect.

The invention discloses a preparation method for peanut bioactive peptide. The method comprises the following steps: adding peanut protein powder to distilled water, carrying out stirring, followed by standing and microwave treatment to obtain peanut protein powder suspension liquid; adjusting a pH value of the peanut protein powder suspension liquid through a hydrochloric acid solution, then adding compound plant hydrolase Viscozyme L, followed by carrying out the microwave treatment to secondarily carry out enzymolysis to obtain a enzymatic hydrolysate, then killing the enzymes and carryingout cooling to a room temperature; adjusting a pH value of the enzymatic hydrolysate through a sodium hydroxide solution or the hydrochloric acid solution, then adding protease and carrying out the microwave treatment to secondarily carry out the enzymolysis, then killing the protease and carrying out cooling to the room temperature, followed by carrying out centrifugating and freeze drying to obtain the peanut bioactive peptide. The prepared peanut bioactive peptide product provided by the present invention has functional properties of high dissolubility, high emulsibility, strong foamability, good emulsion stability, good foam stability and the like. In addition, the method provided by the present invention is applicable for the industrial production.

The invention provides a cascade bent tail plate with a hole groove structure for a suction type transonic velocity plane cascade turbine test bed, which is used for improving a cascade wake flow field of the suction type transonic velocity plane cascade turbine test bed. The tail plate is mainly composed of an inner side curved type tail plate and a hole-shaped or groove-shaped hollow structure on the tail plate, wherein the inner side curved type tail plate comprises two-part geometric structures including a straight segment and a quadratic curve segment, and the tail plate is provided withthe hole-shaped or groove-shaped hollow structure. Under a working condition of a high Mach number large negative attack angle test, usage of a curved shape surface of the tail plate and the hole-shaped or groove-shaped hollow structure on the tail plate can prevent a wake from being over-expanded when the wake disengaging the tail plate to enter a suction channel. The two structures make the pressure of the wake rise to the suction pipeline pressure approaching an outlet at an end section of the tail plate, the over-expansion phenomenon is avoided when the tail plate is disengaged, thereby avoiding damage of turbine plane blade cascade periodicity, and at the same time, it finds through calculation that usage of the bent tail plate have no deterioration in working conditions at differentattack angles of other Mach numbers.

The invention discloses a plant and fruit fermentation stock solution. A preparation method of the plant and fruit fermentation stock solution comprises the following steps: cleaning A-type fruits including 3-5 parts of green plums, 2-4 parts of waxberries, 2-3 parts of strawberries, 3-6 parts of raspberries and 1-2 parts of avocados, wiping and carrying out fermentation; cleaning B-type fruits including 5-6 parts of blueberries, 3-4 parts of mulberries, 5-7 parts of cherries, 3-5 parts of plums, 2-3 parts of prunes and 1-2 parts of wax apples, wiping, feeding 2 parts by weight of maltose, and carrying out fermentation; preparing C-type fruits including 4-5 parts of avocado, 2-3 parts of mangosteens and 1-2 parts of kiwi fruits, and carrying out fermentation; cleaning plants including ginseng which is artificially planted for 4-5 years, Chinese wolfberries, burdock root and pueraria (peeled), and carrying out fermentation; and carrying out fermentation termination treating, namely, uniformly mixing 5 parts of fermentation filtrate of the A-type fruits, 2 parts of fermentation filtrate of the B-type fruits, 1 part of fermentation filtrate of the C-type fruits and 3 parts of fermentation filtrate of the plants to obtain a mixture, immediately putting the mixture into a closed fermentation vat, and continuously fermenting for one month to obtain the finished product of the plant and fruit fermentation stock solution.

The invention discloses an earthworm protein polypeptide preparation, its preparation method and application. The protein polypeptide preparation is prepared by hydrolyzing the earthworm homogenate coarse extract or hydrolyzing the earthworm homogenate coarse extract to obtain the hydrolyzed protein polypeptide, separating by a hyperfiltration membrane with different hole diameter to obtain the protein polypeptide ingredients with different hole diameter. Test proves that the earthworm protein polypeptide preparation has good angiotensin converting enzyme after enzyme hydrolysis and can effectively prevent the high blood pressure. The invention provides a preparation method for the earthworm protein polypeptide preparation with strong operability, high efficiency and realizes an industrialization big production.

The invention discloses methanol gasoline with low gas resistance. The methanol gasoline with low gas resistance is prepared by mixing and blending 60-80 wt% of base oil, 10-15 wt% of constituent oil and 10-30 wt% of denatured methanol, wherein the constituent oil is a mixture composed of 25-30 wt% of aromatic oil and 70-75 wt% of naphtha; the denatured methanol is formed by mixing methanol with a volume ratio of 95-98% and a depressurization additive with a volume ratio of 2-5%; the depressurization additive is prepared by blending the main materials of polymethoxy dimethyl ether with 3-6 polymerization degrees and dimethyl carbonate, and the auxiliary materials of ethanol, isopropanol, ethylene glycol monomethyl ether, methyl tertiary butyl ether, isoamylol and isooctanol. According to methanol gasoline with low gas resistance disclosed by the invention, the saturated vapour pressure of the low-proportion methanol gasoline is obviously decreased by changing the property of the base oil and adding the depressurization additive.

The present invention relates to a stable solid oral pharmaceutical multi-component composition comprising combination of blood pressure lowering drugs with lipid lowering agent/s and optionally a platelet aggregation inhibitor in a single dosage form. The blood pressure lowering agents are selected from β-adrenergic receptor blocking agent, ACE inhibitor and diuretic. The lipid lowering agent is selected from HMG Co-enzyme-A reductase inhibitor. The pharmaceutical composition made as per present invention a) overcomes any drug-drug interactions, b) exhibits pharmacokinetic and pharmacodynamic profile of individual therapeutic agent, c) has minimal side effects. The invention provides multi-component composition (MCC) to increase adherences to therapy. The MCC as per present invention provides compositions that maintain activity of all active ingredients without significant increase in adverse event profile. The present invention further relates to a method of preparing the said pharmaceutical composition.

The present invention features that the crimping surfaces of the bus bar and anode guide rod are cleaned with the cleaning liquid comprising dodecyl benzene sulfonic acid 1-20 wt%, alkali metal hydroxide 0.5-12 wt%, triethanolamine, 1-25 wt%, JFC 0.1-10 wt%, calgon 0.5-10 wt%, ethanol 5-10 wt%, non-ionic surfactant 1-18 wt% and butylcellusolve 5-10 wt% and water (the balance). Washing the anode guide rod with the cleaning liquid can reduce the electrode voltage obviously, lower the power consumption of electrolyzing aluminium greatly.

The invention relates to the field of oil/gas field blowout work depressurizing and provides a hierarchical-depressurizing oil nozzle manifold which comprises a manifold pipeline, a first adjustable oil nozzle connected with the manifold pipeline through a first flat-plate gate valve, a first fixed oil nozzle connected with the manifold pipeline through a second flat-plate gate valve, a second adjustable oil nozzle and a second fixed oil nozzle. The first adjustable oil nozzle and the first fixed oil nozzle are disposed on two sides of the manifold pipeline respectively, and the second adjustable oil nozzle and the second fixed oil nozzle are disposed on the two sides of the manifold pipeline respectively. By the hierarchical-depressurizing oil nozzle manifold, after multistage depressurizing and multiple pressure adjusting of high-pressure fluid during incoming, connection pressure reduction of a pipeline manifold and other parts is prolonged, or part replacement and maintenance probability is reduced, so that production efficiency is improved; due to preferable processing and careful material selection, technical effect of depressurizing of the manifold is better, and the advantages include but are not limited to that service lives of the above parts are prolonged, depressurizing effect is improved, and performance-cost ratio is high.

The invention relates to a pharmaceutical composition containing a calcium channel blocker (CCB) or the mixture thereof, an angiotonin 3II receptor blocker (ARB) or the mixture thereof, statins or the mixture thereof and a pharmaceutically acceptable carrier, wherein the CCB is selected from l-amlodipine, amlodipine, lacidipine, nitrendipine or the mixture thereof; the angiotonin II receptor blocker is selected from telmisartan, losartan, irbesartan, candesartan or the mixture thereof; and the statins are selected from atorvastatin, simvastatin, ruishufatadine, fluvastatin or the mixture thereof. The pharmaceutical composition is used for treating various high blood pressures and preventing or treating cardiovascular and cerebrovascular diseases relevant to the hypertension, reduces the disease rate and/or mortality rate of the cardiovascular and cerebrovascular diseases and also improves the adaptability for a sufferer taking medicine.

The invention relates to an emulsion type crude oil viscosity-reduction drag reduction agent applied to high-wax-content pure oil pipe transportation. The emulsion type crude oil viscosity-reduction drag reduction agent mainly solves the problems that in the prior art, wax crystallization of a pipe network exists and wax asphaltene deposition of a pipe wall are serious in winter, and consequently the pipe transportation capability is greatly lowered, and safety transportation of crude oil is affected by return pressure rising. The emulsion type crude oil viscosity reduction and drag reduction agent is prepared from, by weight, 20-30% of macromolecule terpolymer, 20-35% of polyolefin drag reduction agent, 20-40% of higher alcohol, 5-10% of compound emulsifier and 1-5% of emulsion stabilizer. The emulsion type crude oil viscosity-reduction drag reduction agent can be rapidly dissolved into crude oil, so that the viscosity of the crude oil is reduced, the friction resistance of the crude oil is reduced, return pressure is reduced, and the pipe transportation capability is improved.

The invention relates to a compound control-released percutaneous medicine plaster for treating high blood pressure and its preparation method, wherein the paste comprises laminated back lining layer, a pressure-sensitive adhesive framework form medicament-containing layer and a protective film, wherein the compound medicament comprises diuretics, central alpha-acceptor excitant and cirumferential alpha-receptor blocking agent, beta-receptor blocking agent, calcium antagonist and any two of the five categories of medicament for influencing angiotensin II formation and treating high blood pressure. The invention may realize medicine administration once in front of chest or behind the ears, wherein homeostasis blood concentration can be reached.

The invention discloses a traditional Chinese medicine air sterilization freshening agent and a preparation method thereof. The method provides a formula comprising components in parts by weight as follows: 100-120 parts of indigowoad roots, 40-55 parts of sophorae, 70-80 parts of dandelion, 30-40 parts of flos caryophyllata, 30-35 parts of golden cypress, 5-15 parts of gentian, 5-20 parts of common cnidium fruit, 0-10 parts of glabrous greenbrier rhizome, 30-50 parts of common andrographis herb and 45-60 parts of wild chrysanthemum flower are immersed in an ethanol solution and extracted, a filtrate is collected for filling, and the air-freshening bacteriostatic agent is obtained. The air-freshening bacteriostatic agent can be used for preventing colds and treating respiratory diseases and the like, and can not only inhibit and kill harmful bacteria and viruses in the air, but also expel parasites, relieve itching and prevent virus colds.

The invention discloses a preparation method of a probiotic fermentation pig feed additive. The method comprises the following steps: pre-processing; taking 30-50 parts of locust tree leaf, 30-50 parts of peanut stalk, 20-40 parts of sweet potato vine, 10-30 parts of purslane, 5-15 parts of leaf of Broussonetia Papyrifera, 10-20 parts of pumpkin leaf, 5-10 parts of wild chrysanthemum flower and 20-30 parts of Herba Plantaginis, mixing to obtain a mixture, adding rice washed water having same amount with the mixture, and carrying out pulp refining to obtain a pulp; adding Bacillus subtilis and Aspergillus niger to the obtained pulp, and fermenting to obtain a fermentation stock solution; inoculating a Lactobacillus acidophilus nutrient solution into the fermentation stock solution, and fermenting to obtain a primary fermentation solution; and adding sodium chloride to the primary fermentation solution, carrying out standing fermentation to obtain a secondary fermentation solution, filtering, and recovering and preserving the above obtained filtrate. The additive can increase the nutritional components of feeds, promotes growth, improves the utilization rate of the feeds, enhances the colonization ability of beneficial bacteria in the intestinal tract, promotes digestion and absorption, enhances immunity, improves the disease resistance of bodies, reduces the incidence of diseases, and has no toxic side effects or untoward effects.

The invention relates to the technical field of sealing, in particular to a dynamic sealing device suitable for high speed and high pressure and an aircraft. The dynamic sealing device comprises a sealing shell, a rotating shaft, a liquid sealing wheel and a heat insulation sealing ring, wherein two cavities to be sealed are formed at intervals in the sealing shell, and a through hole making the two cavities communicate is formed in the sealing shell; the rotating shaft can rotate and at least partially penetrate through the through hole; the liquid sealing wheel is arranged on the rotating shaft, can rotate along with the rotation of the rotating shaft and can form a liquid seal between the rotating shaft and the sealing shell when rotating; and the heat insulation sealing ring is arranged between the rotating shaft and the sealing shell and is close to the liquid sealing wheel, and a combined seal is formed between the heat insulation sealing ring and the liquid sealing wheel; the rotating shaft which rotates at a high speed enables the liquid sealing wheel to form a liquid seal between the sealing shell and the rotating shaft, a blocking effect can be achieved for high pressure,the heat insulation sealing ring can achieve a high-temperature insulation effect, the influence of the high temperature on the whole dynamic sealing device is greatly reduced, so that the reliability and the service life of the dynamic sealing device are improved under severe working conditions of high rotating speed, high pressure, and large temperature gradient.

The invention discloses oat biscuit powder capable of lowering blood pressure. The biscuit powder is made of, by weight, 240-280 parts of oat powder, 60-70 parts of buckwheat powder, 14-18 parts of arrowroot powder, 10-15 parts of bitter gourd powder, 20-30 parts of cream powder, 30-40 parts of sunflower seeds, 8-12 parts of asparagus, 6-8 parts of lentinus edodes, 2-3 parts of corn stigma, 3-4 parts of persimmon leaves, 2-3 parts of figs, 1-2 parts of grape leaves, 2-3 parts of Ashitaba, 1-2 parts of cyclocarya paliurus leaves, 2-3 parts of sunflower leaves, 3-4 parts of baking powder and 8-12 parts of nutrition powder. The nutrition powder is made of crab shells and chicken bones, and therefore the biscuit powder can promote bone and marrow growth, nourish the muscle and tendon and treat fractures and has higher nutritive value; premixed biscuit powder is made of the main raw materials of oat powder and buckwheat powder capable of lowering blood pressure and blood sugar and various auxiliary raw materials capable of lowering blood pressure, the premixed biscuit powder only needs to be mixed with an appropriate amount of water to be kneaded into dough, and then the dough can be processed into biscuits; the method is easy and convenient to implement and suitable for household use, the biscuits made through the method are fragrant, sweet, crisp and tasty and have an obvious blood pressure lowering effect.

The invention relates to the field of medicinal preparation, in particular to an amlodipine besylate compound preparation and a preparation method thereof. The preparation is characterized in that each unit preparation consists of 2 to 50mg of amlodipine besylate, 5 to 50mg of olmesartan medoxomil and auxiliary materials, and particularly, each unit preparation contains 10mg of amlodipine besylate and 10mg of olmesartan medoxomil. The invention also discloses a preparation method for the compound preparation. The preparation is used for curing primary hypertension, has good synergistic effect, and offsets adverse effect caused by respective medicament while increasing the effect of reducing hypertension.

The invention relates to a sweet potato leaf probiotics healthy beverage and a preparation method thereof. The sweet potato leaf probiotics healthy beverage is prepared from the following raw material components in parts by weight: 8-15 parts of composite probiotics fluid, 28-32 parts of sweet potato leaf pulp after pasteurization, 10-15 parts of honey and 45-50 parts of water. In the preparation process of the sweet potato leaf probiotics healthy beverage, sweet potato leaves which are low in development degree at present but are rich in nutrient components and good in health-care functions are selected as a main raw material, and through the fermentation process of various beneficial bacteria including lactobacillus casei, bifidobacterium bifidum, saccharomyces cerevisiae and the like, the probiotics beverage having health-care functions is made. The obtained product namely the sweet potato leaf probiotics healthy beverage is rich in nutrients, not only can improve the environment of the intestinal tract but also can prevent and treat diseases, particularly has notable effects in the respects of reducing blood pressure, alleviating constipation and the like, and integrates nutrients and the health-care functions. According to the making method of the sweet potato leaf probiotics healthy beverage disclosed by the invention, a bioengineering technique and a physical technique are used in the whole course, so that the flavor and the full nutrient components of the sweet potato leaf probiotics healthy beverage are greatly maintained, and the nutrient value and the product security of the sweet potato leaf probiotics healthy beverage are extremely high.

The invention relates to a Chinese medicament for treating hypertension and a preparation method thereof and belongs to the technical field of Chinese medicaments. The Chinese medicament for treating hypertension comprises the following medical components in part by weight: chamomile 20-40, flos notoginseng sanchi flower 40-80, raw haw flakes 80-120, cassia seed 80-120, campanumaea pilosula 20-60, lotus plumule 40-80, medlar 50-100 and prunella vulgaris 30-50. The preparation method comprises: (1) washing and grinding the medicaments; (2) mixing and uniformly blending the ground medicaments; and (3) soaking or decocting the ground medicaments in water to obtain the Chinese medicament. A large amount of clinic tests prove that the Chinese medicament has the advantages of remarkable blood pressure reducing effect, short treatment period, no toxic and side effect, simple and convenient preparation process and 95 percent effective rate. In addition, the Chinese medicaments adopted are common medical materials, so the Chinese medicament of the invention has a price far lower than those of common medicaments.

The invention is a calcitonin gene-related polypeptide (CGRP) derivative and its preparing method. CGRP has important physiologic functions of reducing blood pressure, etc, but is easy to degrade in animal bodies and has short acting time. It designs a segment of DNA sequence linked with the GST genes ofEscherichia coli particle carrier pGEX-4T-2, composing a new expression plasmid pGEX-CGRP with CGRP. It makes separation and extraction on the fusion protein produced by Escherichia coli fermentation to prepare CGRP derivative I. In addition, It clones the genes of the two decompressing small peptides: HHL and PRLKPW to CGRP genes, composing two expressing particles: pGEX-CGRP-3AA and pGEX-CGRP-6AA, transferred into the Escherichia coli cells, then fermenting and separating CGRP derivatives II and III from Escherichia coli cells. The above derivatives can be used in preparing the medicines of curing cardiovascular disease.

The invention discloses a compound sustained-release preparation containing felodipine and ramipril and a preparation method of the compound sustained-release preparation, wherein the compound sustained-release preparation is prepared by mixing felodipine sustained-release pellets and ramipril immediate-release pellets according to a specific dose proportion. The felodipine sustained-release pellets can sustainably release for 12 hours, and can be taken once a day, so as to keep the antihypertensive effect for a long time, the ramipril immediate-release pellets can be quickly absorbed so as to achieve the antihypertensive effect and treat the plasma concentration, due to the combination of the two kinds of pellets, the antihypertensive effect can be greatly enhanced, the toxic and side effect of the medicine can be reduced, the administration frequency can be reduced, sustainably stable antihypertensive effect can be achieved in a human body, the patient compliance can be enhanced, the compound sustained-release preparation consists of hundreds and thousands of pellets in uniform particle sizes, so that the damage of individual pellets will not cause burst release of the whole preparation, and compared with the sustained release tablets, the compound sustained-release preparation disclosed by the invention has the advantages of higher safety, lower irritation to gastrointestinal tract, more stable plasma concentration and capability of effectively improving the clinical effect.