Quality control method for traditional Chinese medicine oral liquid for treating psoriasis

Abstract

The invention discloses a quality control method for traditional Chinese medicine oral liquid for treating psoriasis. The medicine is prepared from seven types of medicinal materials such as radix paeoniae rubra, rhizoma smilacis glabrae and glabrous sarcandra herbs. According to the specific quality control method, the thin layer chromatography is applied for conducting thin-layer identification on radix paeoniae rubra and rhizoma smilacis glabrae in PSORI-CMO1, meanwhile, the high performance liquid chromatography is combined for measuring the contents of chlorogenic acid, paeoniflorin, isofraxidin, astilbin and engeletin in the oral liquid, it is guaranteed that detected constituents are accurate and reliable, and the purpose of effectively controlling quality of the traditional Chinese medicine oral liquid can be achieved. By means of the quality control method, the defect that a method for detecting multiple constituents of compound traditional Chinese medicine is complex is overcome; the method has the advantages that by identifying the two types of medicine materials and measuring the contents of important active constituents in the medicine, inherent quality, the treatment effect and stability of a preparation are effectively guaranteed, and controllability of the quality standards for the PSORI-CMO1 oral liquid is improved.

Description

technical field [0001] The invention adopts modern analysis and detection instruments to detect the technical field of traditional Chinese medicine preparations, and relates to a quality control method of oral liquid for treating psoriasis. Background technique [0002] Psoriasis is a recurrent chronic skin disease with a genetic predisposition, and is characterized by erythema and scales induced by multiple factors such as infection, stress, and stress. At present, there are 125 million patients with psoriasis in the world, and there are at least 4 million patients with psoriasis in my country. Because it is difficult to treat, easy to relapse, and hereditary, it can significantly increase the incidence of major diseases such as cardiovascular and cerebrovascular diseases, resulting in Patients have severe psychological pressure, low self-esteem, loss, and even suicidal tendencies, which greatly affect the quality of life of patients. The etiology and pathogenesis of psoria...

AI Technical Summary

Problems solved by technology

[0005] PSORI-CM01 is composed of 7 medicinal materials such as Radix Paeoniae Rubra, Sargassum, and Smilax Poria, and has many active ingredients. According to the 2010 Chinese Pharmacopoeia, the chromatographic conditions and system applicability test methods of each component of the medicinal materials are different, and they are determined one by one. The target component content of each medicinal material in the compound is not conducive to the overall evaluation and control of the quality of the compound Chinese medicine, and it is difficult to ensure the stability and quantity of its active ingredients

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