Bio-enzyme-wrapped microparticle and preparation method and application thereof

A biological enzyme and encapsulation technology, applied in pharmaceutical formulations, cosmetic preparations, cosmetic preparations, etc., can solve the problems of reducing product efficacy, enzyme inactivation, inactivation, etc., to achieve improved retention time, good whitening effect, and effective Good results

Active Publication Date: 2016-08-31
广东百润和健康科技有限公司
View PDF10 Cites 10 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0018] Enzymes in oral care products are easily inactivated by temperature and other ingredients in the formula, especially ionic surfactants commonly used in oral care products, such as sodium lauryl

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Bio-enzyme-wrapped microparticle and preparation method and application thereof
  • Bio-enzyme-wrapped microparticle and preparation method and application thereof
  • Bio-enzyme-wrapped microparticle and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0070] The preparation process of microparticles encapsulating biological enzymes comprises two steps, (1) preparation of proliposomes; (2) encapsulation of proliposomes.

[0071] (1) The present invention adopts the fluidized bed coating method to prepare the proliposome of biological enzyme. Proceed as follows:

[0072] The carrier is pulverized and sieved; and mixed evenly with the biological enzyme powder according to the equal amount incremental method and set aside.

[0073] Dissolve the lipid and polyvinylpyrrolidone in 4 times the amount of absolute ethanol.

[0074] Spray in the mixed bio-enzyme powder by means of fluidized bed rotary cutting spray, dry at 50°C for 50 minutes after spraying, take out and sieve.

[0075] (2) The present invention adopts fluidized bed spray drying technology to wrap the proliposome containing biological enzyme to form the microparticles of wrapped biological enzyme, the steps are as follows:

[0076] Select the core, take the bioenzy...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

PropertyMeasurementUnit
Particle sizeaaaaaaaaaa
Login to view more

Abstract

The invention discloses a bio-enzyme-wrapped microparticle and a preparation method and application thereof. The bio-enzyme-wrapped microparticle comprises a core, a water-soluble shell, a bio-enzyme-wrapped proliposome and a filling agent filling a space among the core, the water-soluble shell and the bio-enzyme-wrapped proliposome, wherein a bio-enzyme is a composition of glucanase and alkaline protease. According to the bio-enzyme-wrapped microparticle and the preparation method and application thereof, the bio-enzyme can stably exist in various oral care products such as toothpaste and tooth powder through a wrapping technique, and the oral care products have the effects of decomposing dental plaques, removing tooth stain, whitening the teeth and refreshing the oral smell.

Description

technical field [0001] The invention relates to the technical field of oral care products, in particular to microparticles coated with biological enzymes and a preparation method and application thereof. Background technique [0002] Teeth whitening has become an important part of human oral health. Along with the improvement day by day of people's living standard, people also strengthen day by day to the concern of tooth whitening. According to the statistics of AC Nielsen, a world-renowned research company, whitening oral care products in my country have become the largest sub-category, with a market size of more than 6 billion yuan. [0003] The development of tooth whitening products is a field that has been studied more in recent years. Exogenous stains on teeth are mainly caused by drinking pigmented beverages, eating pigmented foods and smoking. Whitening oral care products can remove stains on the tooth surface and restore the original color of tooth enamel. Ther...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61K8/02A61K8/14A61K8/66A61K8/73A61K8/60A61Q11/00
CPCA61K8/0245A61K8/14A61K8/60A61K8/66A61K8/731A61K8/732A61Q11/00
Inventor 江山
Owner 广东百润和健康科技有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap