internal parasite control agent

一种内寄生虫、衍生物的技术,应用在药物组合、抗感染药、有机化学等方向,能够解决经济损失、体重损失、贫血等问题

Active Publication Date: 2020-01-24
THE UNIV OF TOKYO +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Namely, as a result of infection with parasites, anemia, malnutrition, frailty, weight loss and severe intestinal wall, tissue and organ damage in infected animals can lead to a decrease in feeding efficiency and productivity, resulting in huge economic losses

Method used

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Examples

Experimental program
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Effect test

Embodiment

[0326] Next, the present invention will be described in detail by citing formulation examples and test examples of the endoparasite control agent of the present invention. It should be noted that the scope of the present invention is not limited by the following formulation examples and test examples.

[0327] In this example, "part" means a mass part.

preparation example 1

[0328] Formulation example 1 (emulsion)

[0329] 10 parts of heterocyclic carboxamide derivatives represented by the general formula (I) of the present invention, 6 parts of Sorpol 355S (manufactured by Toho Chemical, surfactant) and 84 parts of Solvesso 150 (manufactured by Exxon) were stirred and mixed until uniform to obtain emulsion.

preparation example 2

[0330] Preparation example 2 (ointment)

[0331] Fully mix 1 part of the heterocyclic carboxamide derivative represented by the general formula (I) of the present invention, 50 parts of white beeswax, and 49 parts of white petrolatum to obtain an ointment.

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PUM

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Abstract

In order to provide a new parasite control agent such as anthelmintic or antiprotozoal, which has an effective control effect on animal endoparasites that cannot be controlled by conventional anthelmintics or antiprotozoal agents, the present invention provides a general formula An endoparasite control agent in which the heterocyclic carboxamide derivative or its salt shown in (I) is an active ingredient.

Description

technical field [0001] The present invention relates to an agent for controlling endoparasites containing a heterocyclic carboxamide derivative or a salt thereof as an active ingredient, and a method for controlling endoparasites characterized in that the agent is administered orally or parenterally. Background technique [0002] Conventionally, certain carboxamide derivatives are known to have fungicidal activity (for example, see Patent Documents 1 to 13). However, there is no description that the compounds described in this document are effective in expelling or controlling endoparasites parasitic on animals such as mammals and birds. In addition, certain carboxamide derivatives are known to be effective against nematodes that damage crops (for example, see Patent Document 4 or 5), but there is no specific disclosure about the effect against endoparasites that parasitize animals. Furthermore, it has been reported that a compound that inhibits mitochondrial complex II, wh...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/497A61K31/498A61K31/506A61P33/10C07D241/24C07D241/44C07D401/12C07D403/12C07D413/12C07D417/12
CPCC07D403/12C07D413/12C07D241/24C07D417/12C07D213/82C07D231/14C07D401/12A61P33/02A61P33/10
Inventor 北洁诹访明之织田雅次
Owner THE UNIV OF TOKYO
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