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Chinese and western medicine composition for curing liver cirrhosis ascites, and preparation method and application thereof

A technology of liver cirrhosis ascites and Chinese and Western medicine, applied in the field of medicine, can solve the problems of water and electrolyte disorders, slow curative effect of traditional Chinese medicine, long-term use, etc., and achieve the effects of relieving pain, quick results, and improving liver function

Inactive Publication Date: 2017-02-15
郑州莉迪亚医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Western medicine eliminates ascites quickly, focusing on improving liver function, using diuretics to increase the excretion of water and sodium, and promoting the resolution of ascites, but it is easy to cause water and electrolyte disorders
The curative effect of traditional Chinese medicine is slow, and it needs to be used for a long time

Method used

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  • Chinese and western medicine composition for curing liver cirrhosis ascites, and preparation method and application thereof

Examples

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Effect test

Embodiment 1

[0016] In the embodiment of the present invention, a Chinese and Western medicine combination for treating liver cirrhosis ascites is composed of the following raw materials in parts by weight: 7 parts of aminophylline, 1 part of benzbromarone, 11 parts of L-carnitine, and 3 parts of taurine .

[0017] Mix and grind benzbromarone and L-carnitine, pass through a 120-mesh sieve, add deionized water 3.7 times the mass of the two, then raise the temperature to 81°C, and stir at this temperature for 36 minutes to prepare mixture A. Put taurine and aminophylline into the mixture A, then ultrasonically treat at 56°C for 28 minutes with an ultrasonic power of 1000W, then stir at 61°C until dry, and granulate to obtain the combination of Chinese and Western medicines.

Embodiment 2

[0019] In the embodiment of the present invention, a Chinese and Western medicine combination for treating liver cirrhosis ascites is composed of the following raw materials in parts by weight: 15 parts of aminophylline, 5 parts of benzbromarone, 19 parts of L-carnitine, and 7 parts of taurine .

[0020] Mix and grind benzbromarone and L-carnitine, pass through a 120-mesh sieve, add deionized water 3.7 times the mass of the two, then raise the temperature to 83°C, and stir at this temperature for 39 minutes to prepare mixture A. Put taurine and aminophylline into the mixture A, then ultrasonically treat at 56°C for 28 minutes with an ultrasonic power of 1000W, then stir at 61°C until dry, and granulate to obtain the combination of Chinese and Western medicines.

Embodiment 3

[0022] In the embodiment of the present invention, a Chinese and Western medicine combination for treating liver cirrhosis ascites is composed of the following raw materials in parts by weight: 9 parts of aminophylline, 2 parts of benzbromarone, 13 parts of L-carnitine, and 4 parts of taurine .

[0023] Mix and grind benzbromarone and L-carnitine, pass through a 120-mesh sieve, add deionized water 3.7 times the mass of the two, then raise the temperature to 82°C, and stir at this temperature for 37 minutes to prepare mixture A. Put taurine and aminophylline into the mixture A, then ultrasonically treat at 56°C for 28 minutes with an ultrasonic power of 1000W, then stir at 61°C until dry, and granulate to obtain the combination of Chinese and Western medicines.

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Abstract

The invention discloses a Chinese and western medicine composition for curing liver cirrhosis ascites, and a preparation method and an application of the Chinese and western medicine composition. The Chinese and western medicine composition comprises the following materials in parts by weight: 7-15 parts of aminophylline, 1-5 parts of benzbromarone, 11-19 parts of L-carnitine, and 3-7 parts of taurine. The benzbromarone and the L-carnitine are mixed, grinded, and screened by a 120-mesh sieve; deionized water, whose mass is 3.7 times the total mass of both the benzbromarone and the L-carnitine, is added, the temperature is raised to 81-83 DEG C, and the benzbromarone, the L-carnitine and the deionized water are stirred at the temperature for 36-39 minutes to obtain a mixture A; the taurine and the aminophylline are added into the mixture A, ultrasonic treatment is carried out at the temperature of 56 DEG C for 28 minutes, the mixture is then stirred at the temperature of 61 DEG C to dry, and pelletizing is implemented to obtain the Chinese and western medicine composition. The total effective rate of the Chinese and western medicine composition for curing liver cirrhosis ascites is up to more than 98%, the liver function of a patient is improved, the hypoproteinemia is corrected, the ascites is rapidly eliminated, and meanwhile, the complication is reduced. The materials are simple and easy to get, the preparation process is simple, the production cost is low, the curative effect is good, and the Chinese and western medicine composition becomes effective rapidly, has no toxic or side effects, and is suitable for large-scale production and popularization.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a combination of Chinese and Western medicines for treating liver cirrhosis ascites, a preparation method and application thereof. Background technique [0002] Liver cirrhosis is a common clinical chronic progressive liver disease, which is diffuse liver damage caused by long-term or repeated effects of one or more causes. In my country, most of them are post-hepatitis cirrhosis, and a small part are alcoholic cirrhosis and schistosome cirrhosis. Histopathologically, extensive liver cell necrosis, nodular regeneration of residual liver cells, connective tissue hyperplasia, and fibrous septum formation lead to structural destruction of hepatic lobules and formation of pseudolobules. The liver gradually deforms and hardens and develops into cirrhosis. In the early stage, there are no obvious symptoms due to the strong compensatory function of the liver. In the later stage, liver...

Claims

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Application Information

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IPC IPC(8): A61K31/522A61P1/16A61P7/10A61K31/185A61K31/205A61K31/343
CPCA61K31/522A61K31/185A61K31/205A61K31/343
Inventor 不公告发明人
Owner 郑州莉迪亚医药科技有限公司
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