Sodium vitamin C containing chewable tablet and preparation method thereof

A technology for vitamins and chewable tablets, which is applied in the fields of health food, food, and medicine. It can solve the problems of unstable quality of vitamin C, easy oxidation and failure of vitamin C, and unsuitable long-term use. It achieves stable quality, simple preparation, and good stability. Effect

Active Publication Date: 2017-02-22
GUANGXI SANPOTEL HEALTH IND CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The present invention aims at the problems that the existing vitamin C chewable tablets are highly acidic after dissolving, greatly irritating to the oral cavity, throat, esophagus and gastric mucosa, not suitable for long-term use, and vitamin C is easy to oxidize and fail during production and storage, and provides a vitamin C-containing The sodium chewable tablet and the preparation method thereof solve the problems of unstable quality and difficult long-term administration of vitamin C in clinical application

Method used

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  • Sodium vitamin C containing chewable tablet and preparation method thereof
  • Sodium vitamin C containing chewable tablet and preparation method thereof
  • Sodium vitamin C containing chewable tablet and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] The preparation method of the chewable tablet containing vitamin C sodium comprises the following steps:

[0042] S1. Take sodium vitamin C, starch, mannitol, microcrystalline cellulose, povidone K-30, sodium carboxymethyl starch, sodium lauryl sulfate, neotame, pulverize, pass through a 100-mesh sieve, and set aside;

[0043]S2. Weigh each raw and auxiliary material under S1 according to the following parts by weight: sodium vitamin C 30kg, starch 361.75kg, mannitol 10kg, microcrystalline cellulose 60kg, povidone K-30 10kg, sodium carboxymethyl starch 40kg, Sodium lauryl sulfate 10kg, neotame 20kg, mixed uniformly with the method of increasing in equal amounts to obtain mixed powder;

[0044] S3. Take the mixed powder under S2, add 80% ethanol solution to make soft material while stirring, pass through a 20-mesh sieve to granulate, dry at 62°C for 4 hours, control the moisture content to 2-4%, pass through a 20-mesh sieve for granulation, Get particles;

[0045] S4. ...

Embodiment 2

[0047] The preparation method of the chewable tablet containing vitamin C sodium comprises the following steps:

[0048] S1. Take sodium vitamin C, starch, mannitol, microcrystalline cellulose, povidone K-30, sodium carboxymethyl starch, sodium lauryl sulfate, and aspartame respectively, grind them, pass through a 100-mesh sieve, spare;

[0049] S2. Weigh each raw and auxiliary material under S1 according to the following parts by weight: vitamin C sodium 20kg, starch 200kg, mannitol 5kg, microcrystalline cellulose 30kg, povidone K-30 5kg, carboxymethyl starch sodium 10kg, ten Sodium Dialkyl Sulfate 5kg, Aspartame 10kg, mix homogeneously with equal amount increasing method, get mixed powder;

[0050] S3. Take the mixed powder under S2, add 70% ethanol solution to make soft material while stirring, pass through a 30-mesh sieve to granulate, dry at 60°C for 4 hours, control the moisture content to 2-4%, pass through a 30-mesh sieve for granulation, Get particles;

[0051] S4....

Embodiment 3

[0053] The preparation method of the chewable tablet containing vitamin C sodium comprises the following steps:

[0054] S1. Take sodium vitamin C, starch, mannitol, microcrystalline cellulose, povidone K-30, sodium carboxymethyl starch, sodium lauryl sulfate, and mogroside respectively, grind them, pass through a 100-mesh sieve, and set aside ;

[0055] S2. Weigh each raw and auxiliary material under S1 according to the following parts by weight: vitamin C sodium 100kg, starch 500kg, mannitol 20kg, microcrystalline cellulose 100kg, povidone K-30 20kg, carboxymethyl starch sodium 60kg, ten Dialkyl sodium sulfate 20kg, mogroside 30kg, mix uniformly with the method of increasing in equal amounts to obtain mixed powder;

[0056] S3. Take the mixed powder under S2, add 75% ethanol solution to make soft material while stirring, pass through a 14-mesh sieve to granulate, dry at 65°C for 4 hours, control the moisture content to 2-4%, pass through a 14-mesh sieve for granulation, Ge...

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Abstract

The invention discloses a sodium vitamin C containing chewable tablet and a preparation method thereof. The chewable tablet comprises, by weight, 20-100 parts of sodium vitamin C, 100-500 parts of starch, 10-30 parts of sweetening agents, 5-20 parts of mannitol, 30-100 parts of microcrystalline cellulose, 5-20 parts of povidone K-30, 20-60 parts of sodium carboxymethyl starch, 5-20 parts of sodium dodecyl sulfate, 1-5 parts of magnesium stearate and 0.1-0.5 part of peppermint essence. The chewable tablet solves the problems that an existing vitamin C chewable tablet is high in acidity after being dissolved, easily affected with damp and not suitable for taking for a long time, seriously stimulates oral cavities, throat esophagi and gastric mucosa and easily absorbs moisture, vitamin C is easily oxidized and easily loses effect in the storage process and the like. The sodium vitamin C containing chewable tablet is simple and convenient to prepare, fragrant and sweet in taste and stable in quality.

Description

technical field [0001] The invention belongs to the fields of medicine, health food and food, and relates to a composition preparation and a preparation method thereof, in particular to a chewable tablet containing sodium vitamin C and a preparation method thereof. Background technique [0002] Vitamin C is a basic clinical drug or nutritional supplement. It is one of the antioxidant vitamins. It participates in the hydroxylation reaction in the body and is necessary for the formation of intercellular adhesions in bones, teeth, connective tissues and non-epithelial tissues, and can maintain teeth. , the normal function of bones and blood vessels, and increase the resistance to diseases. It is one of the essential nutrients for the human body and is widely used in the prevention and treatment of various diseases. [0003] Tablets are stable in quality and easy to take, and are the most basic and commonly used preparation form. However, for children, the elderly, and patients...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/20A61K31/375A61K47/38A23L33/15A23L33/10A23L29/30A61P3/02A61P31/04A61P7/04A61P21/00A61P25/00A61P9/06A61P13/12A61P35/00A61P9/00A61P37/02
CPCA61K9/0056A61K9/2059A61K31/375A23V2002/00A23V2250/708A23V2200/30A61K9/2013A61K9/2018A61K9/2027A61K9/2054A23L33/15A23G3/368A23G3/42A61P13/12A61P21/00A61P25/00A61P3/02A61P31/04A61P35/00A61P37/02A61P7/04A61P9/00A61P9/06A23L27/32A23L27/33A23L29/055A23L29/262A23L29/04A23L29/219A23L29/37A61K9/2095
Inventor 黄爱强钟文黄爱毅
Owner GUANGXI SANPOTEL HEALTH IND CO LTD
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