Detection method of glycosylated hemoglobin as well as chromatographic test paper strip and assembly method thereof

A technology of glycosylated hemoglobin and chromatographic test paper, which is applied in the detection field of glycosylated hemoglobin content, can solve the problems of high cost and complicated detection of glycosylated hemoglobin, and achieve the effect of simple operation and improved sensitivity and specificity

Active Publication Date: 2017-09-26
海格德生物科技(深圳)有限公司
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Problems solved by technology

[0017] In view of the shortcomings of the above-mentioned prior art, the purpose of the present invention is to provide a detection method for glycated hemoglobin, a chromatography test strip and an assembly method thereof, aiming at solving the problems of cumbersome and high-cost detection of glycated hemoglobin in the prior art

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  • Detection method of glycosylated hemoglobin as well as chromatographic test paper strip and assembly method thereof
  • Detection method of glycosylated hemoglobin as well as chromatographic test paper strip and assembly method thereof
  • Detection method of glycosylated hemoglobin as well as chromatographic test paper strip and assembly method thereof

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Embodiment Construction

[0045] The invention provides a detection method for glycated hemoglobin content, a chromatographic test strip and an assembly method thereof. In order to make the object, technical solution and effect of the present invention more clear and definite, the present invention will be further described in detail below with reference to the accompanying drawings and examples. It should be understood that the specific embodiments described here are only used to explain the present invention, not to limit the present invention.

[0046] figure 1 The chromatographic test strip provided by the embodiment of the present invention can be applied to the detection of the content of glycosylated hemoglobin. Such as figure 1 As shown, the chromatography test strip includes: a bottom plate 100 , a sample loading area 200 , a chromatography reaction area 300 and an attraction area 400 . Wherein, the sample loading area 200 and the suction area 400 are respectively located at two ends of t...

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Abstract

The invention discloses a chromatographic test paper strip which is applied to glycosylated hemoglobin detection. The chromatographic test paper strip comprises a bottom plate, a sampling area for bearing a sample is arranged at one end of the bottom plate, and an attracting area for providing chromatographic power is arranged at the other end; a chromatographic reaction area is formed between the sampling area and the attracting area; a first test line close to the sampling area and a second test line close to the attracting area are sequentially arranged in the chromatographic reaction area; the first test line coats a glycosylated hemoglobin monoclonal antibody; the second test line coats the glycosylated hemoglobin monoclonal antibody. A detection method disclosed by the invention combines the advantages of an immunochromatography and an affinity chromatography; through the detection by the test paper strip with a simple structure and the calculation on the content of the glycosylated hemoglobin, not only are the sensitivity and the specificity of a traditional chromatography improved, but also the detection method is combined with the affinity chromatography, so that the operation is simple and convenient.

Description

technical field [0001] The invention relates to the technical field of chromatography detection, in particular to a detection method for glycated hemoglobin content, a chromatography test strip and an assembly method thereof. Background technique [0002] In recent years, glycosylated hemoglobin (HbA1c) has gradually been paid more and more attention in clinical practice. Glycosylated hemoglobin (HbA1c) is formed by combining some special molecular parts of the hemoglobin A component with glucose through a slow and irreversible non-enzymatic reaction. Therefore, when the concentration of glucose in the blood is high, the amount of glycosylated hemoglobin formed by the human body will also be relatively high. [0003] HbA1c is a biochemical test item with strong convincing, objective data and good stability. It is not affected by an occasional rise or fall in blood sugar, and can reflect the glucose metabolism status of diabetic patients within 2 to 3 months. At the same ti...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/72G01N33/577G01N33/558G01N30/90
CPCG01N30/90G01N33/558G01N33/577G01N33/723G01N2333/805G01N2800/042
Inventor 卢岳军陈雪仇家舟王朝阳钟运华蒋萍
Owner 海格德生物科技(深圳)有限公司
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