A kind of preparation method of Jiruge-6 flavor suppository

A technology of suppositories and alcohol extracts, which is applied in the field of preparation of Jiruge-6 suppositories, can solve the problems of low active ingredient content, inconvenient administration, and limited effect, and achieve improved therapeutic effect, simple process, and simple operation Effect

Active Publication Date: 2021-02-05
INNER MONGOLIA MEDICAL UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Jiruge-6 is a common Mongolian medicine for treating vaginal inflammation. However, the traditional Jiruge-6 is a powder, which is not only inconvenient to administer, unstable in efficacy, but also has low active ingredient content and limited effect
However, there are few studies on the extraction process of functional components in Jiruge-6

Method used

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  • A kind of preparation method of Jiruge-6 flavor suppository
  • A kind of preparation method of Jiruge-6 flavor suppository
  • A kind of preparation method of Jiruge-6 flavor suppository

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preparation example Construction

[0050] And the process steps of the preparation method of Jiruge-6 flavor suppository of the present invention are also relatively simple, specifically can refer to as follows:

[0051] (a) Nepeta, vitex / sour vine, mustard seed, and yarrow are soaked and extracted,

[0052] In this step, the raw materials with volatile oil components are pretreated, and the volatile oil components in these raw materials are extracted by extraction;

[0053] Preferably, in this step, the above four raw materials are soaked in warm water (the water temperature is preferably 30° C.), and soaked for 1-3 hours, for example, preferably soaked for 2 hours;

[0054]Then, the above four raw materials after soaking are reflux extracted with distilled water of 8 to 10 times the mass (in terms of dry weight of the four raw materials). 2 times;

[0055] Then, the volatile oil, water extract and dregs obtained after extraction are recovered separately;

[0056] (b) drying the dregs obtained in step (a), ...

Embodiment 1

[0078] According to the parts by mass, 1 part of nepeta, 2 parts of vitex, 2 parts of yarrow, 3 parts of Polygonatum odoratum, 3 parts of motherwort, and 1 part of mustard seed, respectively weigh appropriate amount of each raw material.

[0079] Then, prepare the Jiruge-6 flavor suppository of embodiment 1 according to the following method:

[0080] (a) Soak nepeta, vitex, mustard seeds and yarrow in water at 30°C for 2 hours, then add 10 times the amount of distilled water, and reflux for 2 hours;

[0081] The extracted volatile oil, water extract and dregs are recovered respectively;

[0082] (b) Dry the dregs obtained in step (a), then mix them with Polygonatum Polygonatum and Motherwort, and then carry out reflux extraction with an ethanol solution with 10 times the mass and a concentration of 70% (v / v), for a total of 3 extractions , extracting for 2 hours each time, collecting the resulting ethanol extract;

[0083] (c) Soak Motherwort and Polygonatum Polygonatum in w...

Embodiment 2

[0090] In terms of parts by mass, 1 part of Schizonepeta, 4 parts of Vitex, 2 parts of Yarrow, 5 parts of Polygonatum odoratum, 5 parts of Motherwort, and 2 parts of Mustard Seed, respectively weigh appropriate amounts of each raw material.

[0091] Then, with reference to the method of embodiment 1, obtain the Jiruge-6 taste suppository of embodiment 2.

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Abstract

The invention provides a preparation method of Jiruge-6 suppository. In the preparation method of the present invention, nepeta, vitex / acantha, yarrow, polygonatum, motherwort, and mustard seeds are used as raw materials, and the method of extracting volatile oil first and then extracting functional components can be used. The functional components in each raw material are effectively extracted, thereby improving the therapeutic effect of Jiruge‑6 Suppository on vaginitis and other gynecological diseases. At the same time, the preparation method of the present invention has simple process and simple operation, and is suitable for large-scale extraction of functional components in raw materials and industrial preparation of Jiruge-6 suppositories.

Description

technical field [0001] The invention relates to the field of pharmaceutical preparations, in particular to a preparation method of Jiruge-6 suppositories. Background technique [0002] Reproductive system inflammation is a common and frequently-occurring disease in women, including vulvitis, vaginitis, cervicitis, endometritis, salpingitis, and pelvic connective tissue inflammation. Vaginitis is the most frequent among female reproductive system diseases. Common vaginitis includes trichomonas vaginitis, candida vaginitis and bacterial vaginosis. Vaginitis is clinically common and is a risk factor for diseases such as AIDS, post-abortion endometritis, miscarriage and premature delivery, and is often overlooked by clinicians. [0003] Western medicine believes that vaginitis is a general term for a variety of vaginal mucosal diseases caused by different diseases. Several mechanisms lead to inflammatory changes in the vagina. Mongolian medicine believes that vaginitis is cau...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/02A61K36/8969A61K47/69A61P15/00A61P15/02A61P29/00
CPCA61K9/0034A61K9/02A61K36/185A61K36/28A61K36/31A61K36/533A61K36/538A61K36/85A61K36/8969A61K47/42A61K2236/331A61K2236/333A61K2236/39A61K2300/00
Inventor 伊丽娜海英昭日格图刘彩红姜清秀萨楚仁贵苏龙高娃
Owner INNER MONGOLIA MEDICAL UNIV
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