Nutritional compositions with 2FL and LNnT for use in inducing a gut microbiota close to the one of breast fed infants

A nutritional composition and microbiome technology, applied in the directions of sugar derivatives, sugar derivatives, food science, etc., can solve the problems of increasing the number of bifidobacteria, regardless of the function of intestinal microorganisms, and reducing the number of Clostridium

Active Publication Date: 2018-03-27
SOC DES PROD NESTLE SA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0019] However, existing interventions using probiotics and / or prebiotics modulate specific microbial taxa, for example, they lead to increased numbers of Bifidobacteria or decreased numbers of Clostridia
However, there is currently no solution to bring the overall microbiota composition (i.e. total / whole / total / total microbiota) of formula-fed infants close to that of breastfed infants
[0020] Existing solutions also don't seem to take gut microbial function into account

Method used

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  • Nutritional compositions with 2FL and LNnT for use in inducing a gut microbiota close to the one of breast fed infants
  • Nutritional compositions with 2FL and LNnT for use in inducing a gut microbiota close to the one of breast fed infants
  • Nutritional compositions with 2FL and LNnT for use in inducing a gut microbiota close to the one of breast fed infants

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0234] Table 1 below gives an example of the composition of a nutritional composition (eg infant formula) according to the present invention. This composition is given by way of example only.

[0235]

[0236]

[0237] Table 1 : Examples of the composition of nutritional compositions (eg infant formulas) according to the invention

Embodiment 2

[0239] Clinical Study Description

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Abstract

The present invention relates to a nutritional composition comprising at least one fucosylated oligosaccharide and at least one N-acetylated oligosaccharide for promoting or inducing a global gut microbiota that is closer to the one of infants fed exclusively with human breast milk, in comparison to infants fed with a conventional nutritional composition. The composition can be an infant formula and is in particular intended for infants between 0 and 12 months of age fed predominantly with infant formula. It promotes a healthy intestinal flora and has beneficial short and long terms effects.

Description

technical field [0001] The present invention relates to nutritional compositions for infants or young children and their health effects. In particular, the present invention relates to infant formulas comprising specific oligosaccharides for inducing a gut microbiota that approximates that of infants fed exclusively with human breast milk (HBM). Background technique [0002] Breastfeeding is recommended for all infants. In some cases, however, breastfeeding is not sufficient or successful for some medical reason, or the mother does not choose to breastfeed. Nutritional compositions, such as infant formulas, have been developed for these conditions. [0003] Nutritional compositions for infants and young children are usually sold as powders to be reconstituted with water, or in some cases as ready-to-drink or concentrated liquid compositions. These compositions are intended to cover most or all of the nutritional needs of an infant or young child. [0004] However, human ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/7028C07H3/06A23L33/135
CPCA61K31/702A61K31/7028A23L33/135A23L33/40C07H3/08C07H13/12
Inventor B·博格N·斯普伦格
Owner SOC DES PROD NESTLE SA
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