27 results about "Human breast milk" patented technology

The present invention concerns isolated human breast milk exosomes, and compositions thereof, and uses of said exosomes and compositions for promoting immunity and treating and / or preventing mucosal immunity and inflammation.

The present invention provides isolated human breast milk exosomes and compositions thereof. The invention also provides an in vitro method for producing the exosome, comprising generating lactating cells derived from human induced pluripotent stem cells (hiPSCs), expressing a human milk-like product from the lactating cells, and purifying the exosome from the human milk-like product.

1. Name of the product in this design: Electric breast pump (XNMD-6610A one-to-two split type). 2. Purpose of this design: For absorbing human breast milk. 3. The key design features of this product are the combination of shape and pattern. 4. The image or photograph that best illustrates the design's key points: a 3D model.

The present invention provides isolated human breast milk exosomes and compositions thereof. The invention also provides an in vitro method for producing the exosome, comprising generating lactating cells derived from human induced pluripotent stem cells (hiPSCs), expressing a human milk-like product from the lactating cells, and purifying the exosome from the human milk-like product. The invention also provides therapeutic uses of isolated human breast milk exosomes and compositions thereof.

Compositions and methods for improving a child, such as an infant's health, are provided. The methods entail improving the quality of breast milk in a female human individual that provides breast milk, or expects to provide breast milk, to the child, by administering to the individual an agent that increases the individual's sensitivity to insulin, and / or an agent that reduces the substrate uptake, synthesis or secretion of long chain fatty acids, reduces the substrate uptake, synthesis or secretion of short chain fatty acids, increases the amino acid uptake, protein synthesis or protein secretion of proteins, or reduces the uptake or synthesis of lactose.

1. Name of the product in this design: Wearable T-junction component (119PP). 2. Purpose of this design: For absorbing human breast milk. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: a 3D model.

The present invention the novel ointment composition based on milkfat obtained from human breast milk and combined with a synergistically beneficial ratio of medium chain triglycerides to milk fat from human breast milk.

A breast shield for expressing human breast milk. The breast shield includes an outer housing and a flexible inner liner within the outer housing. In use, with the breast shield applied to a breast, the inner liner is in contact with the surface of both the areola and nipple of the breast. The breast shield further includes an outer chamber between the outer housing and the inner liner and an inner chamber within the inner liner. In use, the inner and outer chambers, are subjectable to differential pressure and the differential pressure is operable to cause the inner liner to exert a massaging effect against the surface of both the areola and nipple of a breast.

The present invention relates to nutritional compositions and infant formulas that promote brain myelination. More specifically, the present invention relates to nutritional compositions for infants and young children and related health benefits. The present invention relates to a nutritional composition for promoting or supporting an optimal myelination trajectory in the brain, in particular to a nutritional composition comprising a phospholipid, a metabolic precursor thereof and / or a metabolite thereof, for use in promoting or supporting an optimal myelination trajectory in the brain, such trajectory being close to the trajectory observed in infants fed only with human breast milk (HBM) several months before life.

A method of producing mammalian breast milk exosomes, such as human breast milk exosomes, comprising generating lactating cells derived from mammalian breast epithelial cells, such as human breast epithelial cells, expressing mammalian milk-like products, such as human milk-like products, from the lactating cells, and purifying the exosomes from the mammalian milk-like products.

A method for operating a breast pump unit (10) for expressing human breast milk and a breast pump unit (10). The breast pump unit (10) comprises a pump assembly (26) for generating vacuum pressure, a reservoir (24) for receiving breast milk, and a breast shield (11) for sealingly applying to a breast to be pumped. The breast shield (11) comprises a flexible inner chamber (15) for receiving a nipple of the breast and a second chamber (16), in particular an outer chamber extending around the outside of the inner chamber (15) and at least partially surrounding the nipple inserted into the inner chamber (15). The method comprises a cycle comprising: evacuating the inner chamber (15) and the reservoir (24) to a first vacuum pressure by means of a pump assembly (26); connecting a second chamber (16) to the pump assembly (26) and the reservoir (24), and evacuating the second chamber (16) to a second vacuum pressure, wherein the second vacuum pressure is higher than or greater than the first vacuum pressure; and at least partially releasing the vacuum of the second chamber (16) to a lower vacuum pressure, in particular lower than the first vacuum pressure.

The invention provides isolated human breast milk exosomes, and compositions thereof. The present invention also provides in vitro methods for producing said exosomes comprising generating lactocytes derived from human induced pluripotent stem cells (hiPSC), expressing the human milk like product from lactocytes, and purifying the exosomes from the human milk like product. The invention also provides therapeutic uses of the isolated human breast milk exosomes, and compositions thereof.

The present invention concerns isolated human breast milk exosomes, and compositions thereof, and uses of said exosomes and compositions for promoting systemic immunity and treating and / or preventing systemic inflammation.

Concentrating nutrients in breast milk may be achieved using an apparatus comprising a first sheet of material comprising a forward osmotic membrane, a second sheet of material sealed to the first sheet of material about a common outer perimeter thereof, the first sheet of material arranged so that water can traverse the forward osmotic membrane to an interior of the first and second sheets, and a dry carbohydrate within the interior of the first and second sheets exhibiting an osmotic draw property to draw water from un-concentrated, expressed human milk to form concentrated human milk. After a predetermined time, or upon the milk remaining after drawing of water through the membrane being a desired amount, the water draw can end.

The present invention relates to a preterm human milk fortifier composition, more specifically to a preterm milk fortifier composition providing 2′-FL and / or LNFP-I in amounts that are missing in human milk of women who gave birth to a preterm infant. In particular the present invention relates to a fortifier composition designed for infants as a supplement to preterm human breast milk at the time the infant leaves the hospital (discharge) and after. The invention furthermore relates to the use of said preterm human milk fortifier composition.

The present application belongs to the technical field of breast milk biological monitoring, and particularly relates to a method for detecting chemical contaminants in breast milk based on PPAR gamma nuclear receptor affinity selection mass spectrometry, which is used for non-target identification of chemical contaminants in human breast milk, and further evaluates potential PPAR gamma ligands through molecular docking and surface plasmon resonance (SPR). The above detection method links chemical detection directly with receptor-mediated activity, promotes breast milk biological monitoring, makes up for the key knowledge gap of evaluating lactation exposure risk, and provides a basis for discovery and identification of novel contaminants in human breast milk biological monitoring.

A fluid containment and dispensing system includes a variable volume container. The container comprises: an elongate body spanning between a first end and a second end and defining an interior volume between the first end and the second end; a cap coupled to the second end; and a movable floor slidably mounted within the interior volume.

The present disclosure provides a composition and an oil comprising fatty acids. The fatty acids include saturated fatty acids selected from the group consisting of short / medium chain fatty acids, intermediate chain fatty acids, long chain fatty acids, and combinations thereof. The fatty acids also include unsaturated fatty acids selected from the group consisting of monounsaturated fatty acids, polyunsaturated fatty acids, and combinations thereof. The composition and oil can be derived from various sources including recombinant sources, whole milk powder, plant oils, fatty fish, algae, fungi, dairy products, cooking oils, and plant sources. The composition and oil can be used in an infant formula that mimics human breast milk.

The invention provides isolated human breast milk exosomes, and compositions thereof. The present invention also provides in vitro methods for producing said exosomes comprising generating lactocytes derived from mammalian mammary epithelial cells, for example human mammary epithelial cells, expressing the mammalian milk like product, for example the human milk like product from lactocytes, and purifying the exosomes from the mammalian milk like product. The invention also provides therapeutic uses of the isolated human breast milk exosomes, and compositions thereof.

The present invention relates to a human breast milk booster product, comprising combined breast milk from 2 or more individual providers and around 200 000 or more microbiome sequences present in the product (ASVs), in particular around 200 000 or more sequences from viable microbiota. Also provided is a food product comprising the human breast milk booster, use of the human breast milk booster as a food supplement, and the human breast milk booster for use in the treatment of under nourishment, malnourishment or malnutrition. Further provided is a method for producing a human breast milk booster product, comprising combining breast milk obtained from 2 or more individual providers, and concentrating the combined breast milk, thereby producing a concentrated human breast milk booster product comprising around 200 000 or more microbiome sequences present in the product (ASV), in particular around 200 000 or more sequences from viable microbiota.

The present disclosure provides a composition and an oil comprising fatty acids. The fatty acids include saturated fatty acids selected from the group consisting of short / medium chain fatty acids, intermediate chain fatty acids, long chain fatty acids, and combinations thereof. The fatty acids also include unsaturated fatty acids selected from the group consisting of monounsaturated fatty acids, polyunsaturated fatty acids, and combinations thereof. The composition and oil can be derived from various sources including recombinant sources, whole milk powder, plant oils, fatty fish, algae, fungi, dairy products, cooking oils, and plant sources. The composition and oil can be used in an infant formula that mimics human breast milk.

To provide a novel bacterium belonging to Bifidobacterium longum subsp. infantis. Provided is a bacterium belonging to Bifidobacterium longum subsp. infantis, which has an ability to assimilate human breast milk oligosaccharides and xylooligosaccharides and does not have a drug resistance gene.

The present invention concerns an enzymatic process for the preparation of a triglyceride ingredient comprising triglycerides present in human breast milk.

A fluid containment and dispensing system including a spatula sized and configured to be received within an interior volume of a collection container, the spatula including: an elongate body including a central lumen extending through the elongate body; and a wing extending radially from the elongate body for wiping an inner wall of a collection container.

The present disclosure provides a composition and an oil comprising fatty acids. The fatty acids include saturated fatty acids selected from the group consisting of short / medium chain fatty acids, intermediate chain fatty acids, long chain fatty acids, and combinations thereof. The fatty acids also include unsaturated fatty acids selected from the group consisting of monounsaturated fatty acids, polyunsaturated fatty acids, and combinations thereof. The composition and oil can be derived from various sources including recombinant sources, whole milk powder, plant oils, fatty fish, algae, fungi, dairy products, cooking oils, and plant sources. The composition and oil can be used in an infant formula that mimics human breast milk.

A nutrient containment and dispensing system includes a barrel defining an interior volume and having a first opening at a first end and a second opening at a second end; a filter slidably mounted within the interior volume and dividing the interior volume into a first chamber and a second chamber, the filter including a filter media configured to prevent solids and semi-solids from passing through the filter media; and a filter plunger rod configured to engage the filter and move the filter within the interior volume, thereby adjusting a volume of the first chamber and a volume of the second chamber.

The invention provides isolated human breast milk exosomes, and compositions thereof. The present invention also provides in vitro methods for producing said exosomes comprising generating lactocytes derived from human induced pluripotent stem cells (hiPSC), expressing the human milk like product from lactocytes, and purifying the exosomes from the human milk like product. The invention also provides therapeutic uses of the isolated human breast milk exosomes, and compositions thereof.